1
NAPLEX 2024/2025 EXAM QUESTIONS AND VERIFIED
SOLUTIONS ALL CORRECT GRADED A+.
T or F. Beyond use date must be applied to each compounded product using USP
795 guidelines for Nonaqueous Liquids and Solid formulation and for Water-
containing Formulations. - (answers)True
Which of the following is considered with Non-Sterile Preparation? A. USP 795 B.
USP 797 - (answers)A
Labels on Pharmacy-compounded products - Expiration Dates (Beyond Use Dates)
- (answers)* Water containing oral formulations *
> The beyond use date is no later than 14 days when stored at controlled cold
temperature
* Water containing topical/dermal/mucosal liquid and semisolid formulations *
> The beyond use date is no later than 30 days
* Nonaqueous formulations*
> The beyond use date is no later than the time remaining until the earliest
expiration date of any API (use no later than 25% of time of this api) or 6 months,
whichever is earlier
T or F. For capsules, the label must include mcg or mg/capsule? - (answers)True -
Does not require for tablet
T or F. You can rinse compounding equipment with tap water? - (answers)False -
you can only rinse Purified water for rinsing equipment
, 2
What is the best certified sterile compounding environment for injectable
product? Which ISO? - (answers)ISO class 5 (class 100) laminar air flow hood
within ISO class 7 (class 10,000) clean room * with positive air pressure *
differential relative to adjacent areas.
ISO class 5 (class 100) clean room with positive air pressure differential relative to
adjacent areas or a barrier isolator that provides a ISO class 5 (class 100)
environment for compounding
T or F. Liquids in a container curve up, therefore measure at the top of the
meniscus. - (answers)False. Must measure at the bottom of meniscus
What is the difference between glass and Wedge-wood/Porcelain(ceramic)
Mortar and Pestle? - (answers)wedge-wood or porcelain is used commonly and is
best for reducing particle size of dry powders and crystals
Glass is used for liquids or chemical that are oily or that will stain to the porcelain
T or F. It is safe not to use ointment paper to prepare creams and lotions because
these two formulation have the highest content of water. Water content will
cause the paper to moisten, and possibly tear. - (answers)True. we can use
Glassine weighing paper
Which of the following levigating agents are the best to prepare aqueous systems
(O/W dispersions)?
A. Glycerin B. Mineral oil C. Castor oil D. Cottonseed oil E. Tween 80 - (answers)A.
Glycerin
, 3
> Rest are good levigating agents used to prepare oleaginous systems (W/O)
> Additional agents used as levigating agents to prepare aqueous systems consist
of Propylene glycol, polyethylene glycol 80
Sometimes heat is used to mix things easier, but it lead to over-heating which
produce undesired chemical-reactions. What is the best way to prevent over-
heating? - (answers)A water bath will help prevent over-heating
Fill in the blank
........................ refer to a compound prepared without a specific formula (not
from an official compendium) and made specifically to fill the needs of an
individual patient - (answers)Extemporaneous
Fill in the blank
...................... a single agent that is used to soften and smooth the skin. A
moisturizer is sometimes referred to as ................, but the term ............ is used
for single agent, and moisturizers often have coloring, scents, and other
ingredients added - (answers)Emollients
Fill in the blank
Oil in water , or water in Oil is example of ....... - (answers)Emulsions
Fill in the blank
............ Is used to stabilize the emulsion. ........... are usually surfactants (wetting
agents) that reduce the surface tension between the two liquids so that the two
, 4
different substances can move close to each other but they will not be mixed
together - (answers)Emulsifiers
What is the difference between Continental or dry gum method and English, or
wet gum method? - (answers)Both have same ingredients (oil, purified water and
gum (such as acacia) in the ratio of 4:2:1 but the order of mixing is different.
Dry method: gum is mixed rapidly with oil then water added all at once
Wet method: gum is dissolved in water first, then oil is slowly added
What you know about HLB (hydrophilic-Lipophilic balance) number? - (answers)#s
range from 0-20 with 10 being the mid-point means it is the break point between
water and oil solubility. #>10 means hydrophilic (water-soluble) and #<10 means
lipophilic (lipid-soluble)
What is Eutectic Mixture? - (answers)A eutectic mixture is two or more
components that melt at a temperature lower than the melting temperature for
the individual components.
Which of the following are common preservatives?
A. Benzalkonium chloride (BAK)
B. Benzyl alcohol
C. Chlorhexidine
D. Thimerosal (contain mercury)
E. Sodium benzoate
NAPLEX 2024/2025 EXAM QUESTIONS AND VERIFIED
SOLUTIONS ALL CORRECT GRADED A+.
T or F. Beyond use date must be applied to each compounded product using USP
795 guidelines for Nonaqueous Liquids and Solid formulation and for Water-
containing Formulations. - (answers)True
Which of the following is considered with Non-Sterile Preparation? A. USP 795 B.
USP 797 - (answers)A
Labels on Pharmacy-compounded products - Expiration Dates (Beyond Use Dates)
- (answers)* Water containing oral formulations *
> The beyond use date is no later than 14 days when stored at controlled cold
temperature
* Water containing topical/dermal/mucosal liquid and semisolid formulations *
> The beyond use date is no later than 30 days
* Nonaqueous formulations*
> The beyond use date is no later than the time remaining until the earliest
expiration date of any API (use no later than 25% of time of this api) or 6 months,
whichever is earlier
T or F. For capsules, the label must include mcg or mg/capsule? - (answers)True -
Does not require for tablet
T or F. You can rinse compounding equipment with tap water? - (answers)False -
you can only rinse Purified water for rinsing equipment
, 2
What is the best certified sterile compounding environment for injectable
product? Which ISO? - (answers)ISO class 5 (class 100) laminar air flow hood
within ISO class 7 (class 10,000) clean room * with positive air pressure *
differential relative to adjacent areas.
ISO class 5 (class 100) clean room with positive air pressure differential relative to
adjacent areas or a barrier isolator that provides a ISO class 5 (class 100)
environment for compounding
T or F. Liquids in a container curve up, therefore measure at the top of the
meniscus. - (answers)False. Must measure at the bottom of meniscus
What is the difference between glass and Wedge-wood/Porcelain(ceramic)
Mortar and Pestle? - (answers)wedge-wood or porcelain is used commonly and is
best for reducing particle size of dry powders and crystals
Glass is used for liquids or chemical that are oily or that will stain to the porcelain
T or F. It is safe not to use ointment paper to prepare creams and lotions because
these two formulation have the highest content of water. Water content will
cause the paper to moisten, and possibly tear. - (answers)True. we can use
Glassine weighing paper
Which of the following levigating agents are the best to prepare aqueous systems
(O/W dispersions)?
A. Glycerin B. Mineral oil C. Castor oil D. Cottonseed oil E. Tween 80 - (answers)A.
Glycerin
, 3
> Rest are good levigating agents used to prepare oleaginous systems (W/O)
> Additional agents used as levigating agents to prepare aqueous systems consist
of Propylene glycol, polyethylene glycol 80
Sometimes heat is used to mix things easier, but it lead to over-heating which
produce undesired chemical-reactions. What is the best way to prevent over-
heating? - (answers)A water bath will help prevent over-heating
Fill in the blank
........................ refer to a compound prepared without a specific formula (not
from an official compendium) and made specifically to fill the needs of an
individual patient - (answers)Extemporaneous
Fill in the blank
...................... a single agent that is used to soften and smooth the skin. A
moisturizer is sometimes referred to as ................, but the term ............ is used
for single agent, and moisturizers often have coloring, scents, and other
ingredients added - (answers)Emollients
Fill in the blank
Oil in water , or water in Oil is example of ....... - (answers)Emulsions
Fill in the blank
............ Is used to stabilize the emulsion. ........... are usually surfactants (wetting
agents) that reduce the surface tension between the two liquids so that the two
, 4
different substances can move close to each other but they will not be mixed
together - (answers)Emulsifiers
What is the difference between Continental or dry gum method and English, or
wet gum method? - (answers)Both have same ingredients (oil, purified water and
gum (such as acacia) in the ratio of 4:2:1 but the order of mixing is different.
Dry method: gum is mixed rapidly with oil then water added all at once
Wet method: gum is dissolved in water first, then oil is slowly added
What you know about HLB (hydrophilic-Lipophilic balance) number? - (answers)#s
range from 0-20 with 10 being the mid-point means it is the break point between
water and oil solubility. #>10 means hydrophilic (water-soluble) and #<10 means
lipophilic (lipid-soluble)
What is Eutectic Mixture? - (answers)A eutectic mixture is two or more
components that melt at a temperature lower than the melting temperature for
the individual components.
Which of the following are common preservatives?
A. Benzalkonium chloride (BAK)
B. Benzyl alcohol
C. Chlorhexidine
D. Thimerosal (contain mercury)
E. Sodium benzoate
