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Neuroscience (PN2002): Questions With Correct Solutions

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Neuroscience (PN2002): Questions With Correct Solutions

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Neuroscience (PN2002): Questions With Correct
Solutions

Hypoblast Correct Ans - Forms the endoderm

Epiblast Correct Ans - Forms the mesoderm

surface cells Correct Ans - forms ectoderm

Primary Neurulation Correct Ans - - mesodermal cells for notochord
- triggers neural plate formation
- folds to form neural tube

Notochord Correct Ans - - Forms anterior end of primitive streak
- Releases Noggin
- Induces neural plate formation

BMP signaling Correct Ans - allows cell elongation to form neural plate

Dorsal-Ventral gradient Correct Ans - - Dorsal has high levels of BMP
- Ventral has high levels of shh

Rostro-Caudal gradient Correct Ans - - Rostro has low levels of BMP and
high wnt
- Caudal has high levels of BMP, low wnt, and high FGF

Secondary Neurulation Correct Ans - - Mesenchymal cells form neural rod
- transition to epithelial phenotype
- Fuse neural tubes

Pax6 & Sox2 Correct Ans - - induce surface ectoderm thickening
- create future lens placode
- induced by optic vesicle

Vitreous development Correct Ans - - creates shape of eye
- formed from retina mesenchyme cells
- hyaloid artery restriction stops blood flow (forms secondary vitreous)

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