AOBIM/ABIM Exam 46 Questions with Verified Answers,100% CORRECT

AOBIM/ABIM Exam 46 Questions with Verified Answers Howell Jolly bodies - CORRECT ANSWER asplenia, splenectomy Heinze bodies - CORRECT ANSWER g6PD deficiency Bite cells - CORRECT ANSWER g6pd deficiency Which leukemia/lymphoma associated with autoimmune hemolytic anemia - CORRECT ANSWER CLL Hemochromtosis: susceptible to these infections - CORRECT ANSWER Vibrio, listeria, Yersinia Four tests to evaluate a bleeding disorder - CORRECT ANSWER PTT, PT, platelet level, platelet function test (ADP, epinephrine, collagen stimulation) ITP: first and second line treatments? - CORRECT ANSWER 1st line: Steroids; 2nd line: IVIG Treatment for atypical HUS - CORRECT ANSWER Eculizumab. inhibits terminal complement cascade Goal INR for argatroban treatment for HIT II - CORRECT ANSWER INR 4 Post transfusion purpura: when does it occur? - CORRECT ANSWER One week after; no schistocytes on peripheral smear; treatment: IVIG 2 most common types of vWD? - CORRECT ANSWER Type 1 and Type 2a What determines the risk of bleeding - CORRECT ANSWER Dependent on Factor VIII levels. 5% low risk vs. 1% high risk. What is the clinical presentation of Factor XI deficiency? - CORRECT ANSWER Mucosal bleeding. Treatment: FFP, recombinant Factor XI, or desmopressin What is the clinical presentation of Factor XII deficiency? - CORRECT ANSWER Increased PTT. No bleeding. Special test to diagnose Factor XIII deficiency? - CORRECT ANSWER Clot lysis assay Which blood product administration has a higher incidence of bacterial infection and why? - CORRECT ANSWER Platelet transfusion due to it being stored at room temperature How to treat hyperviscosity syndrome in ALL? - CORRECT ANSWER Leukopheresis and hydroxyurea What physical findings are seen in ALL patients? - CORRECT ANSWER Enlarged LNs, splenomegaly, hepatomegaly, enlarged testicles What ALL cytogentic abnormality is associated with poor prognosis? - CORRECT ANSWER 9:22 translocation What are the main differences between ALL and MPD? - CORRECT ANSWER ALL has new cells/blasts whereas MPD has clonal expansion of current cells What is 5q- syndrome? - CORRECT ANSWER A subset of MDS, notably females with thrombocytosis. Favorable prognosis. Tx imatinib