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samenvatting histologie practicum 4

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practicum 4 + foto's

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Practicum 4 : Kraakbeen en bot


L2/13 : trachea en oesofagus – kleuring: trichroom lichtgroen
Algemene opbouw: practicum 2


Hyalien kraakbeen
- Chondrocyten:
➢ in groepjes van 2 of 4 cellen bij elkaar = isogene groepen
➢ omgeven door stevige matrix (onveranderd bij preparatie)
➢ krimpen waardoor duidelijk wordt dat ze in holle ruimte liggen = lacune
in lacune: enkel kernen zichtbaar
lacunes niet altijd samengebundeld tot isogene groepen, kunnen ook individueel voorkomen, meestal dicht tegen perichrondrium


- Tussen lacunes en isogene groepen ligt kraakbeen matrix
Territoriale matrix
➢ vormt donkere rand rond lacunes → hoge concentratie
aan GAG – lage concentratie aan collagene vezels

Interterritoriale matrix
➢ iets lichter gekleurd → lage concentratie GAG – hoge
concentratie collageen type 2


- Omgeven door perichondrium
➢ dicht onregelmatig collageen bindweefsel
➢ vol met kernen van fibroblasten

- Chrondroblasten: aan de rand van kraakbeenstukken, tegen
perichondrium

, Practicum 4 : Kraakbeen en bot

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