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Samenvatting histologie practicum 3

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Practicum 3 + foto's

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Practicum 3 : Klierepitheel en bindweefsel s.s.


E7/39 : glandula submandibularis (speekselklier) – kleuring : trichroom (anilineblauw)




- Exocrien
- Samengestelde vertakte afvoergangen
- Omgeven door bindweefselkapsel (= capsula glandularis)
- Bindweefselsepta verdeelt klierweefsel in lobuli
- Interlobulair bindweefsel bevat bloedvaten en zenuwbundels
- Vnl sereus secreet (eiwitrijk)
- Muceus secreet (glycoproteïnen)
 Seromuceuze speekselklier
- Sereuze kliercellen:
 Verzameld in bolvormige acini, hierrond myoepitheelcellen
 Centraal gelegen ronde kern
 Basofiel RER
 Apicale secretiegranulen; kunnen worden vrijgegeven door
exocytose in lumen van de acinus
- Muceuze kliercellen:
 Verenigd in tubili, bezitten meestal sereus eindstukje = sikkel van
Gianuzzi
 Opstapeling mucus aan apicale celzijde  kern weggedrukt basaal
 Merocriene secretiewijze

, Practicum 3 : Klierepitheel en bindweefsel s.s.




Vrijstelling secretieproducten  afgevoerd naar buitenwereld via afvoergangen
Vanuit klierdeeltjes vertrekken schakelstukken die uitmonden in intralobulaire
kanalen  speekselbuizen of kanalen van Pflüger (éénlagig cilindrisch epitheel)
Lopen verder als interlobulaire kanalen in bindweefsel tussenschotten
Speekselbuizen en interlobulaire kanalen afgelijnd door hetzelfde type
hoogcilindrische epitheelcellen  vertonen basale radiaire streping  kenmerkend
voor ionentransporterende cellen
Interlobulaire kanalen monden uit in groot kanaal van Stenon  afgelijnd door
kubisch – cilinderisch tweelagig epitheel

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