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  • University Of Michigan School Of Nursing
  • Nursing (BIOCHEMISTRY)
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Class notes

Class notes Nursing (Biochemistry)

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2024/2025 Written for academic year
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University Of Michigan School Of Nursing
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Nursing (BIOCHEMISTRY)
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Everything on biochemistry

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BUFFERS AND BUFFERING
SYSTEMS (ROLE OF KIDNEY)

, RENAL CONTROL OF ACID BASE BALANCE
• Can eliminate large amounts of acid
• Can also excrete base
• Can conserve and produce HCO3- ions
• Most effective regulator of pH
• Adjust H+ ion concentration to normal
• It is a slow mechanism that works over a period of hours to several days, but
mechanism.
• If kidneys fail, pH balance fails.
Renal regulation occurs through 3 basic mechanisms:
Secretion of H+ and urine acidification at pH 5.0
Reabsorption of filtered HCO3-
Production of new HCO3-

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