Glycoproteins
Biochemistry
, Glycoproteins
Glycoproteins are proteins that contain oligosaccharide chains (
glycans) covalently attached to their polypeptide side-chains.
The carbohydrate is attached to the protein in a cotranslational or
posttranslational modification in a process is known as glycosylation.
In proteins that have segments extending extracellularly, the
extracellular segments are often glycosylated.
Glycoproteins are often important integral membrane proteins, where
they play a role in cell-cell interactions.
, N-linked protein glycosylation (N-
glycosylation of N-glycans) at Asn residues
(Asn-x-Ser/Thr motifs) in glycoproteins.
Biochemistry
, Glycoproteins
Glycoproteins are proteins that contain oligosaccharide chains (
glycans) covalently attached to their polypeptide side-chains.
The carbohydrate is attached to the protein in a cotranslational or
posttranslational modification in a process is known as glycosylation.
In proteins that have segments extending extracellularly, the
extracellular segments are often glycosylated.
Glycoproteins are often important integral membrane proteins, where
they play a role in cell-cell interactions.
, N-linked protein glycosylation (N-
glycosylation of N-glycans) at Asn residues
(Asn-x-Ser/Thr motifs) in glycoproteins.
