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1. What are the "rights" of medication administration? - ANSWER 1. Right
drug
2. Right dose
3. Right time
4. Right routine
5. Right patient
6. Right documentation
Additional:
- Right reason/indication
- Right to refuse
2. Pharmacology - ANSWER The study/science of drugs that encompasses a
variety of principles
3. Different types of drug names - ANSWER Chemical (chemical composition
and molecular structure)
,Generic name (nonproprietary) - given by US Adopted Names Council
Trade name (proprietary) - registered trademark
4. Pharmaceutics - ANSWER Study of HOW VARIOUS DRUG FORMS
INFLUENCE THE WAY IN WHICH THE DRUG AFFECTED THE BODY
5. Pharmakinetics - ANSWER Study of WHAT THE DRUG DOES TO THE BODY
- Absorption
- Distribution
- Metabolism
- Excretion
6. Pharmacotherapeutics - ANSWER Clinical use of drugs to prevent and treat
diseases
7. Tolerance - ANSWER Decreasing response to repeated drug class
8. Dependence - ANSWER Physiologic or psychological need for a drug
9. Physical Dependence - ANSWER Physiologic need for a drug to avoid
physical withdrawal symptoms
10. Physiological Dependence - ANSWER Also known as addiction; obsessive
desire for the euphoric effects of a drug
,11. Toxicology - ANSWER SCIENCE OF THE ADVERSE EFFECTS OF CHEMICALS
ON LIVING ORGANISMS
12. Enteral Route - ANSWER Drug is absorbed into the systemic circulation
through THE ORAL OR GASTRIC MUCOSA OR SMALL INTESTINE
- Oral (PO)
- Sublingual (SL)
- Buccal
- Rectal (topical)
13. Parenteral Route - ANSWER - Intravenous (IV - fastest into the blood
circulation)
- Intramuscular (IM)
- Subcutaneous
- Can also be intradermal, intraatrial, intrathecal, and intraarticular
14. Topical Route - ANSWER Skin (includes transdermal patches)
- Eyes
- Ears
- Nose
, - Lungs (inhalation)
- Rectum
- Vagina
15. First Pass Effect - ANSWER Large portion of the drug is chemically
changed into inactive metabolites by the liver and a much smaller amount will be
available
- TAKEN ORALLY OR INTERALLY ONLY
Albumin - ANSWER Most common blood protein and CARRIES THE MAJORITY
OF PROTEIN-BOUND DRUG MOLECULES
Metabolism (biotransformation) - ANSWER BIOCHEMICAL ALTERATION OF A
DRUG INTO AN INACTIVE METABOLITE
Prodrug - ANSWER Must metabolize to turn the drug on
What is the organ for metabolism? - ANSWER LIVER
Cytochrome P-450 Enzymes - ANSWER Or microsomal enzymes
- Help liver to breakdown
- Only lipid soluble drugs