1
NAVLE Dog
An 8-year old female Chow Chow presents to you with difficulty eating. On oral
exam, you see a 3 cm mass in the caudal maxilla. You cannot FNA the mass but
R
can aspirate an enlarged mandibular lymph node (the results are seen in the
E
image). In addition to surgery and radiation, which of the following is an approved
H
treatment option for the disease you would mention to the owner?
IG
a. ONCEPT
b. mitoxatrone
H
c. vincristine
G
d. palladia
e. doxorubicin
IN
a. ONCEPT vaccine
Y
the image shows metastatic melanoma (see the black melanin pigment)
FL
ONCEPT vaccine is the "melanoma" vaccine for dogs for therapeutic and cancer
treatment
--> Doxorubicin, vincristine, mitoxantrone are human meds used off label in vet
oncology NOT for melanoma
, 2
--> Palladia is used for mast cell tumors
ER
Pilonidal (dermoid) sinus, a congenital condition most commonly seen in
H
Rhodesian Ridgeback dogs, is most often located in or on which of the following
G
areas?
I
A) Dorsal midline between the neck and sacrum
B) Eyelids
H
C) Interdigital web
G
D) Perianal region
N
E) Ventral midline between the muzzle and abdomen
I
Dorsal midline between neck and sacrum
If a dog presents with an elevated BMBT time prior to surgery, what should you
Y
administer before cutting?
L
desmopressin acetate
Osteosarcoma F
-activated release of Von Willebrand factors helping the dog with clotting
malignant tumor of the bone
large/giant breed dogs (rare in cats, better prognosis)
, 3
non-specific signs; lameness, pain on palpation, decreased activity, pathological
fracture
R
RADS:
E
-lytic bone lesions, moth-eaten appearance
H
-proliferative component
-3 view chest rads (first place to spread)
TX:
IG
H
-no treatment (weeks)
G
-amputation (3 months)
-chemo + radiation + surgery (up to 12 months)
Prognosis:
IN
Y
-Elevated ALP = poor prognostic indicator
L
Toward the knee, away from the elbow
F
Osteosarcoma
Negative Prognostic indicator for a GDV
elevated lactate (>6 mmol/L)
long onset of presentation (5-6 hrs)
recumbency at time of presentation
any need for resection or splenectomy
, 4
Positive Ortolani exam
pain on extension of hips
palpable crepitation over hips
bunny hop gait
R
hip dysplasia
diagnose:
HE
-orthopedic examination
G
-radiographs (OFA, Penn HIP, Standard Hip extension VD/L)
I
-radiographically see:
H
*<50% head coverage, osteophyte formation, joint laxity, remodeling, sclerosis
G
treat:
N
-NSAID therapy
I
-weight management
Y
-nutraceutical s
L
-conservative exercise (i.e., physical therapy)
F
-Surgical (TPO if younger (No evidence of OA) Total hip Replacement, FHO if OA
present
Hyperthermia results in
protein denaturation, apoptosis, activation of heat shock protein
--> CV collapse
NAVLE Dog
An 8-year old female Chow Chow presents to you with difficulty eating. On oral
exam, you see a 3 cm mass in the caudal maxilla. You cannot FNA the mass but
R
can aspirate an enlarged mandibular lymph node (the results are seen in the
E
image). In addition to surgery and radiation, which of the following is an approved
H
treatment option for the disease you would mention to the owner?
IG
a. ONCEPT
b. mitoxatrone
H
c. vincristine
G
d. palladia
e. doxorubicin
IN
a. ONCEPT vaccine
Y
the image shows metastatic melanoma (see the black melanin pigment)
FL
ONCEPT vaccine is the "melanoma" vaccine for dogs for therapeutic and cancer
treatment
--> Doxorubicin, vincristine, mitoxantrone are human meds used off label in vet
oncology NOT for melanoma
, 2
--> Palladia is used for mast cell tumors
ER
Pilonidal (dermoid) sinus, a congenital condition most commonly seen in
H
Rhodesian Ridgeback dogs, is most often located in or on which of the following
G
areas?
I
A) Dorsal midline between the neck and sacrum
B) Eyelids
H
C) Interdigital web
G
D) Perianal region
N
E) Ventral midline between the muzzle and abdomen
I
Dorsal midline between neck and sacrum
If a dog presents with an elevated BMBT time prior to surgery, what should you
Y
administer before cutting?
L
desmopressin acetate
Osteosarcoma F
-activated release of Von Willebrand factors helping the dog with clotting
malignant tumor of the bone
large/giant breed dogs (rare in cats, better prognosis)
, 3
non-specific signs; lameness, pain on palpation, decreased activity, pathological
fracture
R
RADS:
E
-lytic bone lesions, moth-eaten appearance
H
-proliferative component
-3 view chest rads (first place to spread)
TX:
IG
H
-no treatment (weeks)
G
-amputation (3 months)
-chemo + radiation + surgery (up to 12 months)
Prognosis:
IN
Y
-Elevated ALP = poor prognostic indicator
L
Toward the knee, away from the elbow
F
Osteosarcoma
Negative Prognostic indicator for a GDV
elevated lactate (>6 mmol/L)
long onset of presentation (5-6 hrs)
recumbency at time of presentation
any need for resection or splenectomy
, 4
Positive Ortolani exam
pain on extension of hips
palpable crepitation over hips
bunny hop gait
R
hip dysplasia
diagnose:
HE
-orthopedic examination
G
-radiographs (OFA, Penn HIP, Standard Hip extension VD/L)
I
-radiographically see:
H
*<50% head coverage, osteophyte formation, joint laxity, remodeling, sclerosis
G
treat:
N
-NSAID therapy
I
-weight management
Y
-nutraceutical s
L
-conservative exercise (i.e., physical therapy)
F
-Surgical (TPO if younger (No evidence of OA) Total hip Replacement, FHO if OA
present
Hyperthermia results in
protein denaturation, apoptosis, activation of heat shock protein
--> CV collapse
