CMN 552 Exam 1 Test Questions With
Guaranteed Pass Solutions.
What two neurotransmitters are most implicated in the pathophysiology of mood disorders? - Answer
norepinephrine and serotonin
How are dopamine levels affected in depression and mania? - Answer Dopamine activity may be
reduced in depression and increased in mania
How does depression affect sleep neurophysiology? - Answer Loss of deep (slow-wave) sleep
Increase in nocturnal arousal.
The latter is reflected by four types of disturbance: (1) an increase in nocturnal awakenings, (2) a
reduction in total sleep time, (3) increased phasic rapid eye movement (REM) sleep, and (4) increased
core body temperature. T
What is the most common abnormality found in structural and functional brain imaging in depressive
disorders? - Answer Increased frequency of abnormal hyperintensities in subcortical regions, such as
periventricular regions, the basal ganglia, and the thalamus
What cognitive distortions are commonly seen in depressed patients? - Answer (1) views about the self
—a negative self-precept, (2) about the environment—a tendency to experience the world as hostile and
demanding, and (3) about the future—the expectation of suffering and failure
What is learned helplessness? - Answer the hopelessness and passive resignation an animal or human
learns when unable to avoid repeated aversive events
What "specifiers" are used to describe patients with various mood disorders? - Answer Table 8.1-7
What factors are associated with a poor prognosis for patients with mood disorders? - Answer MDD:
The percentage of patients recovering after repeated hospitalization decreases with passing time.
Generally, as a patient experiences more and more depressive episodes, the time between the episodes
decreases, and the severity of each episode increases.
,Bipolar I: Have a poorer prognosis than do patients with major depressive disorder. About 40 to 50
percent of patients with bipolar I disorder may have a second manic episode within 2 years of the first
episode. poor occupational status, alcohol dependence, psychotic features, depressive features,
interepisode depressive features, and male gender were all factors that contributed a poor prognosis.
Short duration of manic episodes, advanced age of onset, few suicidal thoughts, and few coexisting
psychiatric or medical problems predict a better outcome.
Bipolar II: The course and prognosis of bipolar II disorder indicate that the diagnosis is stable because
there is a high likelihood that patients with bipolar II disorder will have the same diagnosis up to 5 years
later. Bipolar II disorder is a chronic disease that warrants long-term treatment strategies.
What is endogenous depression? - Answer depression with no apparent cause
What characteristics would the clinician see if a patient presented with atypical features in a depressed
patient? - Answer Catatonic features
Postpartum onset
Rapid cycling
Seasonal features
Significant weight gain
Hypersomnia
Leaden paralysis
What diagnostic criteria are required for a patient to receive a diagnosis of Major Depressive Disorder? -
Answer *Five (or more) of the following symptoms have been present during the same 2-week period
and represent a change from previous functioning; at least one of the symptoms is either (1) depressed
mood or (2) loss of interest or pleasure.
Depressed most of the day, nearly every day as indicated by subjective report (e.g., feels sad, empty,
hopeless) or observation made by others (e.g., appears tearful)
Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day
(as indicated by subjective account or observation)
, Significant weight loss when not dieting or weight gain (e.g., change of more than 5% of body weight in a
month), or decrease or increase in appetite nearly every day
Insomnia or hypersomnia nearly every day
Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective
feelings of restlessness or being slowed down)
Fatigue or loss of energy nearly every day
Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day
(not merely self-reproach or guilt about being sick).
Diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective
account or as observed by others)
Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan,
or a suicide attempt or a specific plan for committing suicide
The symptoms cause clinically significant distress or impairment in social, occupational, or other
important areas of functioning.
The episode is not attributable to the physiological effects of a substance or to another medical
condition.
The occurrence of the major depressive episode is not better explained by schizoaffective disorder,
schizophrenia, schizophreniform disorder, delusional disorde
What are some common sleep disturbances experienced by patients with MDD? - Answer Insomnia,
hypersomnia.
Guaranteed Pass Solutions.
What two neurotransmitters are most implicated in the pathophysiology of mood disorders? - Answer
norepinephrine and serotonin
How are dopamine levels affected in depression and mania? - Answer Dopamine activity may be
reduced in depression and increased in mania
How does depression affect sleep neurophysiology? - Answer Loss of deep (slow-wave) sleep
Increase in nocturnal arousal.
The latter is reflected by four types of disturbance: (1) an increase in nocturnal awakenings, (2) a
reduction in total sleep time, (3) increased phasic rapid eye movement (REM) sleep, and (4) increased
core body temperature. T
What is the most common abnormality found in structural and functional brain imaging in depressive
disorders? - Answer Increased frequency of abnormal hyperintensities in subcortical regions, such as
periventricular regions, the basal ganglia, and the thalamus
What cognitive distortions are commonly seen in depressed patients? - Answer (1) views about the self
—a negative self-precept, (2) about the environment—a tendency to experience the world as hostile and
demanding, and (3) about the future—the expectation of suffering and failure
What is learned helplessness? - Answer the hopelessness and passive resignation an animal or human
learns when unable to avoid repeated aversive events
What "specifiers" are used to describe patients with various mood disorders? - Answer Table 8.1-7
What factors are associated with a poor prognosis for patients with mood disorders? - Answer MDD:
The percentage of patients recovering after repeated hospitalization decreases with passing time.
Generally, as a patient experiences more and more depressive episodes, the time between the episodes
decreases, and the severity of each episode increases.
,Bipolar I: Have a poorer prognosis than do patients with major depressive disorder. About 40 to 50
percent of patients with bipolar I disorder may have a second manic episode within 2 years of the first
episode. poor occupational status, alcohol dependence, psychotic features, depressive features,
interepisode depressive features, and male gender were all factors that contributed a poor prognosis.
Short duration of manic episodes, advanced age of onset, few suicidal thoughts, and few coexisting
psychiatric or medical problems predict a better outcome.
Bipolar II: The course and prognosis of bipolar II disorder indicate that the diagnosis is stable because
there is a high likelihood that patients with bipolar II disorder will have the same diagnosis up to 5 years
later. Bipolar II disorder is a chronic disease that warrants long-term treatment strategies.
What is endogenous depression? - Answer depression with no apparent cause
What characteristics would the clinician see if a patient presented with atypical features in a depressed
patient? - Answer Catatonic features
Postpartum onset
Rapid cycling
Seasonal features
Significant weight gain
Hypersomnia
Leaden paralysis
What diagnostic criteria are required for a patient to receive a diagnosis of Major Depressive Disorder? -
Answer *Five (or more) of the following symptoms have been present during the same 2-week period
and represent a change from previous functioning; at least one of the symptoms is either (1) depressed
mood or (2) loss of interest or pleasure.
Depressed most of the day, nearly every day as indicated by subjective report (e.g., feels sad, empty,
hopeless) or observation made by others (e.g., appears tearful)
Markedly diminished interest or pleasure in all, or almost all, activities most of the day, nearly every day
(as indicated by subjective account or observation)
, Significant weight loss when not dieting or weight gain (e.g., change of more than 5% of body weight in a
month), or decrease or increase in appetite nearly every day
Insomnia or hypersomnia nearly every day
Psychomotor agitation or retardation nearly every day (observable by others, not merely subjective
feelings of restlessness or being slowed down)
Fatigue or loss of energy nearly every day
Feelings of worthlessness or excessive or inappropriate guilt (which may be delusional) nearly every day
(not merely self-reproach or guilt about being sick).
Diminished ability to think or concentrate, or indecisiveness, nearly every day (either by subjective
account or as observed by others)
Recurrent thoughts of death (not just fear of dying), recurrent suicidal ideation without a specific plan,
or a suicide attempt or a specific plan for committing suicide
The symptoms cause clinically significant distress or impairment in social, occupational, or other
important areas of functioning.
The episode is not attributable to the physiological effects of a substance or to another medical
condition.
The occurrence of the major depressive episode is not better explained by schizoaffective disorder,
schizophrenia, schizophreniform disorder, delusional disorde
What are some common sleep disturbances experienced by patients with MDD? - Answer Insomnia,
hypersomnia.
