1. Which type of sterile compounding procedure is classified as
high-risk according to USP <797>?
A. Compounding with a non-sterile ingredient
B. Compounding using only sterile ingredients
C. Compounding in a cleanroom environment
D. Compounding in a Class II Biological Safety Cabinet
Answer: A) Compounding with a non-sterile ingredient
Rationale: High-risk procedures involve the use of non-sterile
ingredients or equipment, increasing the risk of microbial
contamination or unsafe preparation.
2. Which of the following is the correct order of steps for garbing
before entering a sterile compounding area?
A. Hand hygiene, don gown, don gloves, don mask
B. Don gloves, don gown, hand hygiene, don mask
C. Don gown, hand hygiene, don gloves, don mask
D. Hand hygiene, don gown, don mask, don gloves
Answer: D) Hand hygiene, don gown, don mask, don gloves
Rationale: The proper order ensures that the compounding area is
as clean as possible before introducing the personnel into the
environment.
,3. Which of the following is required when preparing compounded
sterile preparations that involve hazardous drugs?
A. Preparing them in a Class II biological safety cabinet (BSC)
B. Preparing them in an open-air environment
C. Preparing them in a non-sterile hood
D. Preparing them in a laminar airflow workbench
Answer: A) Preparing them in a Class II biological safety cabinet
(BSC)
Rationale: Hazardous drugs must be compounded in a Class II
BSC, which provides both containment and sterility assurance to
protect the compounding personnel and the environment.
4. Which of the following is considered a critical factor in sterile
compounding that ensures the protection of patient health?
A. The speed of drug preparation
B. The sterility of compounded drugs
C. The appearance of the preparation
D. The cost of the compounded preparation
Answer: B) The sterility of compounded drugs
Rationale: The sterility of compounded preparations is the most
critical factor, as it directly impacts patient safety and health by
preventing infections and other complications.
, 5. In which of the following scenarios would a pharmacist need to
prepare a compounded sterile preparation in a cleanroom
environment?
A. When preparing an injectable medication
B. When preparing oral suspensions
C. When preparing a tablet formulation
D. When preparing topical preparations
Answer: A) When preparing an injectable medication
Rationale: Injectable medications are considered sterile
preparations and must be compounded in a cleanroom
environment to maintain sterility.
6. According to USP <797>, how long should sterile compounding
personnel perform hand hygiene before entering the cleanroom?
A. At least 10 seconds
B. At least 20 seconds
C. At least 30 seconds
D. At least 1 minute
Answer: B) At least 20 seconds
Rationale: Hand hygiene should be performed for at least 20
seconds to thoroughly cleanse the hands of contaminants before
entering the sterile compounding area.
high-risk according to USP <797>?
A. Compounding with a non-sterile ingredient
B. Compounding using only sterile ingredients
C. Compounding in a cleanroom environment
D. Compounding in a Class II Biological Safety Cabinet
Answer: A) Compounding with a non-sterile ingredient
Rationale: High-risk procedures involve the use of non-sterile
ingredients or equipment, increasing the risk of microbial
contamination or unsafe preparation.
2. Which of the following is the correct order of steps for garbing
before entering a sterile compounding area?
A. Hand hygiene, don gown, don gloves, don mask
B. Don gloves, don gown, hand hygiene, don mask
C. Don gown, hand hygiene, don gloves, don mask
D. Hand hygiene, don gown, don mask, don gloves
Answer: D) Hand hygiene, don gown, don mask, don gloves
Rationale: The proper order ensures that the compounding area is
as clean as possible before introducing the personnel into the
environment.
,3. Which of the following is required when preparing compounded
sterile preparations that involve hazardous drugs?
A. Preparing them in a Class II biological safety cabinet (BSC)
B. Preparing them in an open-air environment
C. Preparing them in a non-sterile hood
D. Preparing them in a laminar airflow workbench
Answer: A) Preparing them in a Class II biological safety cabinet
(BSC)
Rationale: Hazardous drugs must be compounded in a Class II
BSC, which provides both containment and sterility assurance to
protect the compounding personnel and the environment.
4. Which of the following is considered a critical factor in sterile
compounding that ensures the protection of patient health?
A. The speed of drug preparation
B. The sterility of compounded drugs
C. The appearance of the preparation
D. The cost of the compounded preparation
Answer: B) The sterility of compounded drugs
Rationale: The sterility of compounded preparations is the most
critical factor, as it directly impacts patient safety and health by
preventing infections and other complications.
, 5. In which of the following scenarios would a pharmacist need to
prepare a compounded sterile preparation in a cleanroom
environment?
A. When preparing an injectable medication
B. When preparing oral suspensions
C. When preparing a tablet formulation
D. When preparing topical preparations
Answer: A) When preparing an injectable medication
Rationale: Injectable medications are considered sterile
preparations and must be compounded in a cleanroom
environment to maintain sterility.
6. According to USP <797>, how long should sterile compounding
personnel perform hand hygiene before entering the cleanroom?
A. At least 10 seconds
B. At least 20 seconds
C. At least 30 seconds
D. At least 1 minute
Answer: B) At least 20 seconds
Rationale: Hand hygiene should be performed for at least 20
seconds to thoroughly cleanse the hands of contaminants before
entering the sterile compounding area.
