BIOCHEM EXAM 1 NEW EDITION 2025/2026 QUESTIONS
WITH 100% ACCURATE ANSWERS
Affinity Means - Stickiness for oxygen
high altitudes - not much oxygen
developing baby get their oxygen from - its mother so its haemoglobin needs to be a little stickier for
haemoglobin
high affinity - stickiness of oxygen
myoglobin job is to - store oxygen does not transport it like muscles
haemoglobin job is to - pick up oxygen in the lungs and deliver it to your tissues
haemoglobin has 4 - protein subunits
myoglobin has 1 - protein subunits
each protein subunit has a - heme group and in each heme group their are iron and iron binds with
oxygen
haemoglobin can carry and transport __ oxygen of molecules at a time while myoglobin can carry __
oxygen molecules at a time - 4, 1
cooperatively - feature of haemoglobin that enables it to pick up oxygen in the lungs while dropping
it off in other tissues.
ex: table with chairs
___ binds to the same site of haemoglobin that oxygen binds. However, it binds much stronger than
oxygen and cooperatively of 4 subunits make it look occupied. because it has such a high affinity for
haemoglobin that___ is unlikely to get up from the table its like holding oxygen has a hostage -
carbon monoxide
,___ will pick up oxygen very readily but it can never drop it off of the tissues that need it, that why
carbon monoxide exhibits its harmful effects - haemoglobin
when __ binds to carbon monoxide it creates a pink colour. example: person looks pink = carbon
monoxide poisoning - haemoglobin
high affinity for oxygen
stores oxygen
1 subunit - myoglobin
lower affinity for oxygen
transports oxygen
exhibits cooperatively
4 subunits - hemoglobin
which class of amino acid is most likely to be located on the exterior of hemoglobin? why?
Tip: polar= hydrophillic
nonpoler= hydrophobic
charge - polar, charge
because hydrophilic
sickle cell anemia results when someone inherits 2 mutant copies of the HBB gene, which is on
chromes 11. what is the mode of inheritance?
Tip: chromsome11 means autosomal trait
, sex link is on x chromosome
inherit 2 mutant copies= recessive
you only have to get 1 bad copy to get disease= dominant - autosomal recessive
we want hemoglobin to pick up and stick to oxygen. in the___ hemoglobin has a high affinity for
oxygen.
- low hydrogen
- find in relax state
-higher ph
- low carbon dioxide - lung
we want hemoglobin to drop off oxygen, so we need it to be less sticky or have a lower affinity.
-most likely found in tense state
-low ph= carbon dioxide react with water to form acid leads to this
-high carbon dioxide=active tissue produces
- lots of hydrogen ion=because of low ph - muscle
-muscle
-tense
-subunits are further apart
-favored at low ph
-heme is domed
-stabalized by 2,3-bpge - deoxygenated hemoglobin
-lung
-relaxed
-subunits are closer together
- favored at high ph
-heme is planar
WITH 100% ACCURATE ANSWERS
Affinity Means - Stickiness for oxygen
high altitudes - not much oxygen
developing baby get their oxygen from - its mother so its haemoglobin needs to be a little stickier for
haemoglobin
high affinity - stickiness of oxygen
myoglobin job is to - store oxygen does not transport it like muscles
haemoglobin job is to - pick up oxygen in the lungs and deliver it to your tissues
haemoglobin has 4 - protein subunits
myoglobin has 1 - protein subunits
each protein subunit has a - heme group and in each heme group their are iron and iron binds with
oxygen
haemoglobin can carry and transport __ oxygen of molecules at a time while myoglobin can carry __
oxygen molecules at a time - 4, 1
cooperatively - feature of haemoglobin that enables it to pick up oxygen in the lungs while dropping
it off in other tissues.
ex: table with chairs
___ binds to the same site of haemoglobin that oxygen binds. However, it binds much stronger than
oxygen and cooperatively of 4 subunits make it look occupied. because it has such a high affinity for
haemoglobin that___ is unlikely to get up from the table its like holding oxygen has a hostage -
carbon monoxide
,___ will pick up oxygen very readily but it can never drop it off of the tissues that need it, that why
carbon monoxide exhibits its harmful effects - haemoglobin
when __ binds to carbon monoxide it creates a pink colour. example: person looks pink = carbon
monoxide poisoning - haemoglobin
high affinity for oxygen
stores oxygen
1 subunit - myoglobin
lower affinity for oxygen
transports oxygen
exhibits cooperatively
4 subunits - hemoglobin
which class of amino acid is most likely to be located on the exterior of hemoglobin? why?
Tip: polar= hydrophillic
nonpoler= hydrophobic
charge - polar, charge
because hydrophilic
sickle cell anemia results when someone inherits 2 mutant copies of the HBB gene, which is on
chromes 11. what is the mode of inheritance?
Tip: chromsome11 means autosomal trait
, sex link is on x chromosome
inherit 2 mutant copies= recessive
you only have to get 1 bad copy to get disease= dominant - autosomal recessive
we want hemoglobin to pick up and stick to oxygen. in the___ hemoglobin has a high affinity for
oxygen.
- low hydrogen
- find in relax state
-higher ph
- low carbon dioxide - lung
we want hemoglobin to drop off oxygen, so we need it to be less sticky or have a lower affinity.
-most likely found in tense state
-low ph= carbon dioxide react with water to form acid leads to this
-high carbon dioxide=active tissue produces
- lots of hydrogen ion=because of low ph - muscle
-muscle
-tense
-subunits are further apart
-favored at low ph
-heme is domed
-stabalized by 2,3-bpge - deoxygenated hemoglobin
-lung
-relaxed
-subunits are closer together
- favored at high ph
-heme is planar
