SOLUTIONS
A compound containing N-acetylneuraminic acid (sialic acid) is:
Correct Answers ganglioside GM2.
A convenient cloning vector with which to introduce foreign
DNA into E. coli is a(n): Correct Answers plasmid.
A hydropathy plot is used to: Correct Answers predict whether
a given protein sequence contains membrane-spanning
segments.
A ligand-gated ion channel (such as the nicotinic acetylcholine
receptor) is: Correct Answers a membrane protein that permits
an ion to pass through the membrane only when opened by the
appropriate ligand.
A major component of RNA but not of DNA is: Correct
Answers uracil.
A process not involving the fusion of two membranes or two
regions of the same membrane is: Correct Answers entry of
glucose into cells
ABC transporters are not known to facilitate the following
process: Correct Answers moving vitamin E into lipocytes
An electrogenic Na+ transporter: Correct Answers transports
Na+ without concurrent transport of any other charged species.
,An example of a glycerophospholipid that is involved in cell
signaling is: Correct Answers phosphatidylinositol
An integral membrane protein can be extracted with: Correct
Answers a solution containing detergent.
Autophosphorylation of receptor tyrosine kinases depends on
which of the following? Correct Answers All of the above
B-form DNA in vivo is a ________-handed helix, _____ Å in
diameter, with a rise of ____ Å per base pair. Correct Answers
right; 20; 3.4
Based on Chargaff's rules, which of the following are possible
base compositions for double-stranded DNA? %A %G %C %T
%U Correct Answers 5 45 45 5 0
Biological waxes are all: Correct Answers esters of single fatty
acids with long-chain alcohols.
Calmodulin is a(n): Correct Answers regulatory subunit of
calcium-dependent enzymes.
Certain restriction enzymes produce cohesive (sticky) ends. This
means that they: Correct Answers make a staggered double-
strand cut, leaving ends with a few nucleotides of single-
stranded DNA protruding.
Chargaff's rules state that in typical DNA: Correct Answers A
+ G = T + C.
, Cholera and pertussis toxins are: Correct Answers All of the
above
Common features found in a cloning plasmid used for protein
expression include all except which of the following? Correct
Answers Telomeric ends
Compounds that generate nitrous acid (such as nitrites, nitrates,
and nitrosamines) change DNA molecules by: Correct Answers
deamination of bases.
Consider the transport of glucose into an erythrocyte by
facilitated diffusion. When the glucose concentrations are 5 mM
on the outside and 0.1 mM on the inside, the free-energy change
for glucose uptake into the cell is: (These values may be of use
to you: R = 8.315 J/mol·K; T = 298 K; 9 (Faraday constant) =
96,480 J/V; N = 6.022 1023/mol.) Correct Answers about 10
kJ/mol.
Consider the transport of K+ from the blood (where its
concentration is about 4 mM) into an erythrocyte that contains
150 mM K+. The transmembrane potential is about 60 mV,
inside negative relative to outside. The free-energy change for
this transport process is: (These values may be of use to you: R
= 8.315 J/mol.K; T = 298 K; 9 (Faraday constant) = 96,480 J/V;
N = 6.022 1023/mol.) Correct Answers about 15 kJ/mol.
Current estimates indicate that ________ % of the human
genome is translated into protein. Correct Answers roughly
1.5%