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Samenvatting stelselmatige weefselleer: geslachtsstelsel

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(Behaalde score: 17/20) Deze samenvatting bevat alle info uit de slides inclusief de extra uitleg van de prof uit de les. Handig voor de meerkeuzevragen.

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Geslachtsstelsel of genitaal systeem

Mannelijk geslachtsstelsel

1. Testis en afvoerwegen

 Bouw scrotum
o Epidermis
o Dermis
 Tunica dartos (musculo-elastische laag)
 Temperatuur, septum scrotale
 Omwille van descensus testis  verschillende bladen rond teelbal
o Fascia v/h scrotum
o Tunica vaginalis
 Hydrocoele
o M. cremaster
 Afgesplitst van M.obliquus abdominis internus & transversus
o Tunica albuginea
 Mediastinum testis
o Tunica vasculosa
 Tubuli seminiferi = zaadbuisjes
o Spermatogeen epitheel
 Sertolicellen
 Zonulae occludentes
 Testisvloeistof
 ABP (FSH afh)
 Inhibine (inhibeert vrijstelling FSH)
 Zaadcellen
 Spermatogoniën A en B
 Spermatocyt 1
 Spermatocyt 2
 Spermatide vroeg/laat
 Spermatozoa
 Spermatogenese:
1) Spermatocytogenesis
2) 2 meiotische delingen (van spermatocyt 1 en 2)
3) Spermiogenesis
A) Acrosoomvorming
B) 2 centriolen  basaalkorrel & cytoskelet flagel
C) Mitochondriën rond flagel
D) Kern denser & afgevlakt
E) Overtollig cytoplasma naar achter valt weg samen met
GA als restlichaampje gefagocyteerd door Sertolicellen 
alleen acrosoom rest
 Hormonale interacties:
- GnRH (hypothalamus)
- LH en FSH (hypofyse)
- Testosteron (Leydigcellen)
- ABP (sertolicellen)
- Inhibin (sertolicellen)

, o Myoïde cellen = contractiële cellen
o Interstitium (los bw) met intersitiële celeln van Leydig en veel capillairen
 Leydigcellen
 Testosteron
 Ducti
o Intratesticulair
 Tubuli recti
 Rete testis
o Extratesticulair
 Ductulus efferens
 Mucosa : kubisch EP afgewisseld met cilindrisch pseudomeerl EP
 Muscularis: dunne laag circulair geschikte gladde spiercellen
 Sterk gevasculariseerd los BW
 (coni vasculosi)
 Epididymis
 Mucosa: pseudotweelagig trilhaarepitheel
 Muscularis: dunne laag circulair geschikte gladde spiercellen + in
staartregio aangevuld met bi. En bui. Long laag
 Intersitium
 Ductus deferens***
 Mucosa: EP idem epid., fibro-elastisch LP, onreg. Stervormig lumen
 Muscularis: 3 lagen glad SW (long. Binnenlaag, circ. Middenlaag,
longit. Buitenlaag)
 Adventitia
 (sterilisatie)
 Ampulla
 Mucosa : kubisch EP, GEEN stereociliën meer, losmazige LP
 Muscularis: versmald dun, binnenste circ laag, buitenste long laag
 Adventitia: los
 Ductus ejaculatorius
 Mucosa: 1-lagig kubisch in bovenste deel en overgangsEP thv
urethra, LP met elastinevezels, spierelementen
 Uitmonding in pars prostatica van urethra thv colliculus seminalis

***Funiculus spermaticus = zaadstreng
- Ductus deferens
- Zenuwen
- Bloedvaten (A. en V.  plexus pampiniformis)
- Spier (M. cremaster)

2. Klieren

 Vesiculae seminales = zaadblaasjes
o Mucosa: kubisch, secreterend, lipofuscine EP, elastische LP
o Muscularis: bi. Circulaire laag, bui longit. Laag
o Adventitia: elastisch losmazig
 Prostaat
o Samenvoeging van tubuloacineuze klieren
o 4 zones:
1) Anterieur fibromusculair stroma
2) Centrale zone (20%) – omgeeft ductus ejaculatorius

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