Medical Biochemistry 2 Test Bank
Chapter 1: Carbohydrate Metabolism
MCQs:
1.
The rate-limiting enzyme in glycolysis is:
a) Hexokinase
b) Phosphofructokinase-1 (PFK-1)
c) Pyruvate kinase
d) Glucose-6-phosphatase
2.
1. Answer: b) Phosphofructokinase-1 (PFK-1)
3.
The Cori cycle involves the conversion of:
a) Glucose to pyruvate
b) Lactate to glucose
c) Pyruvate to acetyl-CoA
d) Glycogen to glucose
4.
1. Answer: b) Lactate to glucose
5.
Which pathway is responsible for the generation of NADPH?
a) Glycolysis
b) Pentose phosphate pathway
c) TCA cycle
d) Urea cycle
6.
1. Answer: b) Pentose phosphate pathway
True/False:
1. Gluconeogenesis primarily occurs in the liver and kidneys. (True)
2. The TCA cycle directly produces ATP. (False, it produces GTP and
reduced coenzymes.)
Short Answer:
Describe the regulation of glycolysis by insulin and glucagon.
, Chapter 2: Lipid Metabolism
MCQs:
1.
Beta-oxidation of fatty acids occurs in the:
a) Cytoplasm
b) Mitochondria
c) Endoplasmic reticulum
d) Golgi apparatus
2.
o Answer: b) Mitochondria
3.
The enzyme responsible for cholesterol biosynthesis is:
a) HMG-CoA reductase
b) Acetyl-CoA carboxylase
c) Lipoprotein lipase
d) Pyruvate dehydrogenase
4.
o Answer: a) HMG-CoA reductase
5.
Ketone bodies are produced when:
a) Blood glucose levels are high
b) Insulin levels are high
c) Fatty acid oxidation exceeds energy demands
d) The TCA cycle is overactive
6.
o Answer: c) Fatty acid oxidation exceeds energy demands
True/False:
1. LDL is considered "bad" cholesterol because it transports cholesterol to
tissues. (True)
2. Fatty acid synthesis occurs in the mitochondria. (False, it occurs in the
cytoplasm.)
Short Answer:
Chapter 1: Carbohydrate Metabolism
MCQs:
1.
The rate-limiting enzyme in glycolysis is:
a) Hexokinase
b) Phosphofructokinase-1 (PFK-1)
c) Pyruvate kinase
d) Glucose-6-phosphatase
2.
1. Answer: b) Phosphofructokinase-1 (PFK-1)
3.
The Cori cycle involves the conversion of:
a) Glucose to pyruvate
b) Lactate to glucose
c) Pyruvate to acetyl-CoA
d) Glycogen to glucose
4.
1. Answer: b) Lactate to glucose
5.
Which pathway is responsible for the generation of NADPH?
a) Glycolysis
b) Pentose phosphate pathway
c) TCA cycle
d) Urea cycle
6.
1. Answer: b) Pentose phosphate pathway
True/False:
1. Gluconeogenesis primarily occurs in the liver and kidneys. (True)
2. The TCA cycle directly produces ATP. (False, it produces GTP and
reduced coenzymes.)
Short Answer:
Describe the regulation of glycolysis by insulin and glucagon.
, Chapter 2: Lipid Metabolism
MCQs:
1.
Beta-oxidation of fatty acids occurs in the:
a) Cytoplasm
b) Mitochondria
c) Endoplasmic reticulum
d) Golgi apparatus
2.
o Answer: b) Mitochondria
3.
The enzyme responsible for cholesterol biosynthesis is:
a) HMG-CoA reductase
b) Acetyl-CoA carboxylase
c) Lipoprotein lipase
d) Pyruvate dehydrogenase
4.
o Answer: a) HMG-CoA reductase
5.
Ketone bodies are produced when:
a) Blood glucose levels are high
b) Insulin levels are high
c) Fatty acid oxidation exceeds energy demands
d) The TCA cycle is overactive
6.
o Answer: c) Fatty acid oxidation exceeds energy demands
True/False:
1. LDL is considered "bad" cholesterol because it transports cholesterol to
tissues. (True)
2. Fatty acid synthesis occurs in the mitochondria. (False, it occurs in the
cytoplasm.)
Short Answer:
