Nurs 615 Pharm Exam 1 - Maryville
Study online at https://quizlet.com/_56ytfw
Low albumin = more free
How does hypoalbumine- drug (bc the drug can't
mia affect the process of bind to albumin aka pro-
prescribing? tein) = increased adverse
effects
is considered a contraindi-
What is a Black Box Warn-
cation to administer that
ing:
drug.
Half-life specifically means
the amount of time it takes
What is the drugs half-life? for an administered drug
to be halfway cleared from
the system.
the time between drug ad-
ministration and maximum
Peak of action: concentration of drug in
the blood stream. Best
therapeutic effect.
the time between onset of
action and metabolism of
drug below the minimum
Duration of action:
needed for an effect. The
length of time you have the
drug in your system.
, Nurs 615 Pharm Exam 1 - Maryville
Study online at https://quizlet.com/_56ytfw
According to the WHO
The first step is to define
what is the first step in the
the patient's problem
prescribing process?
specify the therapeutic ob-
The second step is to
jective
choose which drug or
The third step is to
treatment is needed.
Step 4 of the WHO ap-
Start the treatment
proach:
Step 5 of the WHO ap-
Educate the patient
proach:
Step 6 of the WHO ap-
Monitor the treatment
proach:
Phase 1 of drug develop- The drug is tested on
ment: healthy volunteers
trials with people who have
Phase 2 of drug develop- the disease for which the
ment: drug is thought to be effec-
tive
Large numbers of patients
in medical research cen-
ters receive the drug in
phase 3. This larger sam-
, Nurs 615 Pharm Exam 1 - Maryville
Study online at https://quizlet.com/_56ytfw
pling provides information
about infrequent or rare
Phase 3 of drug develop- adverse effects. The FFA
ment: will approve a new drug ap-
plication if phase 3 studies
are satisfactory.
This phase is voluntary
and involves postmarket
surveillance of the drug's
therapeutic effects at the
completion of phase 3. The
pharmaceutical company
receives reports from doc-
Phase 4 of drug develop- tors and other health care
ment: professionals about the
therapeutic results and ad-
verse effects of the drug.
Some medications, for ex-
ample, have been found to
be toxic and have been re-
moved from the market af-
ter their initial release.
much of the drug is
lost in the absorption
process. The liver metabo-
, Nurs 615 Pharm Exam 1 - Maryville
Study online at https://quizlet.com/_56ytfw
lizes many drugs, thus re-
Explain first pass metabo-
duces the bioavailabilty of
lism
the drug.
The fastest route of ab-
What is the fasted route of sorption is inhalation, and
absorption: not as mistakenly consid-
ered the IV administration.
The GI tract is lined with
epithelial cells; drugs must
Why does the GI tract take permeate through these
longer to absorb? cells in order to be ab-
sorbed into the circulatory
system.
the cell membrane. Cell
membranes are essential-
ly lipid bilayers which form
a semipermeable mem-
What is One particular cel- brane. Pure lipid bilay-
lular barrier that may pre- ers are generally perme-
vent absorption of a given able only to small and
drug? uncharged solutes, hence
whether or not a molecule
is ionized will affect its ab-
sorption, since ionic mole-
cules are charged.
Study online at https://quizlet.com/_56ytfw
Low albumin = more free
How does hypoalbumine- drug (bc the drug can't
mia affect the process of bind to albumin aka pro-
prescribing? tein) = increased adverse
effects
is considered a contraindi-
What is a Black Box Warn-
cation to administer that
ing:
drug.
Half-life specifically means
the amount of time it takes
What is the drugs half-life? for an administered drug
to be halfway cleared from
the system.
the time between drug ad-
ministration and maximum
Peak of action: concentration of drug in
the blood stream. Best
therapeutic effect.
the time between onset of
action and metabolism of
drug below the minimum
Duration of action:
needed for an effect. The
length of time you have the
drug in your system.
, Nurs 615 Pharm Exam 1 - Maryville
Study online at https://quizlet.com/_56ytfw
According to the WHO
The first step is to define
what is the first step in the
the patient's problem
prescribing process?
specify the therapeutic ob-
The second step is to
jective
choose which drug or
The third step is to
treatment is needed.
Step 4 of the WHO ap-
Start the treatment
proach:
Step 5 of the WHO ap-
Educate the patient
proach:
Step 6 of the WHO ap-
Monitor the treatment
proach:
Phase 1 of drug develop- The drug is tested on
ment: healthy volunteers
trials with people who have
Phase 2 of drug develop- the disease for which the
ment: drug is thought to be effec-
tive
Large numbers of patients
in medical research cen-
ters receive the drug in
phase 3. This larger sam-
, Nurs 615 Pharm Exam 1 - Maryville
Study online at https://quizlet.com/_56ytfw
pling provides information
about infrequent or rare
Phase 3 of drug develop- adverse effects. The FFA
ment: will approve a new drug ap-
plication if phase 3 studies
are satisfactory.
This phase is voluntary
and involves postmarket
surveillance of the drug's
therapeutic effects at the
completion of phase 3. The
pharmaceutical company
receives reports from doc-
Phase 4 of drug develop- tors and other health care
ment: professionals about the
therapeutic results and ad-
verse effects of the drug.
Some medications, for ex-
ample, have been found to
be toxic and have been re-
moved from the market af-
ter their initial release.
much of the drug is
lost in the absorption
process. The liver metabo-
, Nurs 615 Pharm Exam 1 - Maryville
Study online at https://quizlet.com/_56ytfw
lizes many drugs, thus re-
Explain first pass metabo-
duces the bioavailabilty of
lism
the drug.
The fastest route of ab-
What is the fasted route of sorption is inhalation, and
absorption: not as mistakenly consid-
ered the IV administration.
The GI tract is lined with
epithelial cells; drugs must
Why does the GI tract take permeate through these
longer to absorb? cells in order to be ab-
sorbed into the circulatory
system.
the cell membrane. Cell
membranes are essential-
ly lipid bilayers which form
a semipermeable mem-
What is One particular cel- brane. Pure lipid bilay-
lular barrier that may pre- ers are generally perme-
vent absorption of a given able only to small and
drug? uncharged solutes, hence
whether or not a molecule
is ionized will affect its ab-
sorption, since ionic mole-
cules are charged.
