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Solid Oral Dosage Forms
Created @February 3, 2025 3:53 PM
Class Molecules to Medicine
Disperse System
Two-phase system where the insoluble (Solid particles) or immiscible
dispersed (Liquid droplets) phase is distributed through continuous phase
Advantages of Solid Dosage Forms
Convenient and clean
Economic- Light and compact
Stable- Dry
Accurate dose
Possible controlled release
Can mask taste
Flexibility in formulation
Disadvantages of Solid Dosage Forms
Difficult to swallow
Fixed dose
Quantity of the drug difficult to adjust
Difficult for liquid drugs
Solid Oral Dosage Forms 1
, Tablets
Single dose of one or more active substances
A result of compressing particles all w/ the same volume
Oral administration
Shapes from 50mg→500mg
Properties
Strength
Able to withstand shock from manufacturing, packaging, shipping,
dispensing and use
Efficacy
Drug content needs to be bioavailable, release must be easily copied
to other formulations
Safety
Needs to be chemically and physically stable
Same weight
Same amount of drug
Tablet Types
Uncoated/coated
Orodispersible (Dissolves in saliva)
Carbonated
Chewable
Buccal
Solid Oral Dosage Forms 2
Solid Oral Dosage Forms
Created @February 3, 2025 3:53 PM
Class Molecules to Medicine
Disperse System
Two-phase system where the insoluble (Solid particles) or immiscible
dispersed (Liquid droplets) phase is distributed through continuous phase
Advantages of Solid Dosage Forms
Convenient and clean
Economic- Light and compact
Stable- Dry
Accurate dose
Possible controlled release
Can mask taste
Flexibility in formulation
Disadvantages of Solid Dosage Forms
Difficult to swallow
Fixed dose
Quantity of the drug difficult to adjust
Difficult for liquid drugs
Solid Oral Dosage Forms 1
, Tablets
Single dose of one or more active substances
A result of compressing particles all w/ the same volume
Oral administration
Shapes from 50mg→500mg
Properties
Strength
Able to withstand shock from manufacturing, packaging, shipping,
dispensing and use
Efficacy
Drug content needs to be bioavailable, release must be easily copied
to other formulations
Safety
Needs to be chemically and physically stable
Same weight
Same amount of drug
Tablet Types
Uncoated/coated
Orodispersible (Dissolves in saliva)
Carbonated
Chewable
Buccal
Solid Oral Dosage Forms 2
