2025 LATEST UPDATED| NURS 660 PSYCHOPHARM EXAM 4 LATEST
MARYVILLE UNIVERSITY COMPLETE 200 QUESTIONS AND
CORRECT DETAILED ANSWERS WITH RATIONALES|ALREADY
GRADED A+
Typical antipsychotics - (answers)What class of antipsychotic are these Neuroleptics,
Conventional, First Generation, Dopamine Receptor Antagonists?
Atypical Antipsychotics - (answers)What class of antipsychotic are these Second Generation,
Serotonin-Dopamine Receptor Antagonists
Dopamine D2 receptor - (answers)This receptor has the benefit of reducing positive symptoms.
请您
Possible side effects include: Parkinsonism, akathisia, tardive dyskinesia, endocrine effects such
as prolactin secretion, menstrual changes and sexual dysfunction.
Serotonin 5-H2a receptor - (answers)This receptor has the benefit of reducing EPS
Possible side effects: Sexual dysfunction
Serotonin 5HT2c receptor - (answers)The benefit of this receptor is unknown
Side effect is weight gain
Histamine H-1 receptor - (answers)The benefit of this receptor is sedation
Side effects are sedation, increased appetite, weight gain and hypotension
Muscarinic cholinergic receptors - (answers)The benefit of the receptor is that it reduces EPS
Side effects are autonomic changes such as blurry vision, dry mouth, constipation, urinary
retention, tachycardia and memory dysfunction.
a1-adrenergic receptors - (answers)Benefit of receptor unknown
Side effects are orthostatic hypertension, dizziness and reflex tachycardia.
, a2-adrenergic receptors - (answers)Benefit of receptor unknown
Side effects are drug interactions
D2-Agonist actions? - (answers)What makes an antipsychotic conventional?
D2 antagonist/First generation antipsychotics/Conventional antipsychotics/Typical
antipsychotics - (answers)These antipsychotics share the primary pharmacological property of
D2 antagonism, which is responsible not only for their antipsychotic efficacy, but also for many
of their side effects.
请您
Conventional Antipsychotic - (answers)These drugs have pharmacological properties in addition
to D2 antagonism, they block muscarinic cholinergic receptors, histamine h-1 receptors and/or
a1-adrenergic receptors.
60-80% - (answers)Antipsychotic properties happen when how much of the D2 receptor is
blocked?
80% - (answers)The degree of binding in the mesolimbic pathway needed for antipsychotic
effects is?
extrapyramidal side effects - (answers)When greater that 80% of D2 receptors are occupied in
the dorsal striatum what happens?
Pituitary gland - (answers)Which organ is associated with hyperprolactinemia?
Aliphatic Phenothiazines (Chlorpromazine, Levomepromazine, Promazine and Triflupromazine)
- (answers)These group of Phenothiazine medications are low/medium potency agents, with high
sedation, medium anti-muscarinic effects, and medium extrapyramidal side effects.
MARYVILLE UNIVERSITY COMPLETE 200 QUESTIONS AND
CORRECT DETAILED ANSWERS WITH RATIONALES|ALREADY
GRADED A+
Typical antipsychotics - (answers)What class of antipsychotic are these Neuroleptics,
Conventional, First Generation, Dopamine Receptor Antagonists?
Atypical Antipsychotics - (answers)What class of antipsychotic are these Second Generation,
Serotonin-Dopamine Receptor Antagonists
Dopamine D2 receptor - (answers)This receptor has the benefit of reducing positive symptoms.
请您
Possible side effects include: Parkinsonism, akathisia, tardive dyskinesia, endocrine effects such
as prolactin secretion, menstrual changes and sexual dysfunction.
Serotonin 5-H2a receptor - (answers)This receptor has the benefit of reducing EPS
Possible side effects: Sexual dysfunction
Serotonin 5HT2c receptor - (answers)The benefit of this receptor is unknown
Side effect is weight gain
Histamine H-1 receptor - (answers)The benefit of this receptor is sedation
Side effects are sedation, increased appetite, weight gain and hypotension
Muscarinic cholinergic receptors - (answers)The benefit of the receptor is that it reduces EPS
Side effects are autonomic changes such as blurry vision, dry mouth, constipation, urinary
retention, tachycardia and memory dysfunction.
a1-adrenergic receptors - (answers)Benefit of receptor unknown
Side effects are orthostatic hypertension, dizziness and reflex tachycardia.
, a2-adrenergic receptors - (answers)Benefit of receptor unknown
Side effects are drug interactions
D2-Agonist actions? - (answers)What makes an antipsychotic conventional?
D2 antagonist/First generation antipsychotics/Conventional antipsychotics/Typical
antipsychotics - (answers)These antipsychotics share the primary pharmacological property of
D2 antagonism, which is responsible not only for their antipsychotic efficacy, but also for many
of their side effects.
请您
Conventional Antipsychotic - (answers)These drugs have pharmacological properties in addition
to D2 antagonism, they block muscarinic cholinergic receptors, histamine h-1 receptors and/or
a1-adrenergic receptors.
60-80% - (answers)Antipsychotic properties happen when how much of the D2 receptor is
blocked?
80% - (answers)The degree of binding in the mesolimbic pathway needed for antipsychotic
effects is?
extrapyramidal side effects - (answers)When greater that 80% of D2 receptors are occupied in
the dorsal striatum what happens?
Pituitary gland - (answers)Which organ is associated with hyperprolactinemia?
Aliphatic Phenothiazines (Chlorpromazine, Levomepromazine, Promazine and Triflupromazine)
- (answers)These group of Phenothiazine medications are low/medium potency agents, with high
sedation, medium anti-muscarinic effects, and medium extrapyramidal side effects.
