W7 EXAM NSAIDS, OSTEO,
AUTOIMMUNE/INFLAMM DXS (KELLIWILSON1
PHARM MUSCUOLSKELETAL), (DROOPYHALO
NSG 6005 WEEK 7 PHARMACOLOGY),
(SHIPHIE_PHILIPOSE MU NURS 615: ADVANCED
PHARM - CHAPTER 25 STUDY GUIDE) EXAM
QUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) ||ALREADY GRADED
A+||NEWEST VERSION
Quiz: Aspirin (exotrin) ASA
What should you remember?
Ans: 1. Most POTENT inhibitor of prostaglandin synthesis
2. Inhibit platelet aggregation 7-10 days (life span)
3. Reye's syndrome (children) chickenpox, influenza, & other viral disorders
4. hypersensitivity prevalent in those with asthma, nasal polyposis, chronic
uritcaria
5. tinnitus and diiness with elevated bl levels
6. caution liver and renal insufficiency
7. NO PREGNANCY cat D (used in infertility and toximia)
8. NO BFing
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,2
9. GI ulcer risk↑
10. LOTS of interactionszz
Quiz: Acetaminophen (tylenol) APAP
What should you remember?
o
o
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,3
Ans: 1. MAX 3 g/day
2. reduce fever by direct act hypothalamus=(vaso dil, sweating)
3. ETOH limit ≤2 g/day, hepatotoxicity and hepatic failure reported even with
therapeutic doses
4. minimal inhibition of protaglandidn synthesis=clinically insignificant
antirheumatic or anti-inflammatory effects
5. NO platelet aggregation, NO affect on prothrombin response, No production
of GI ulcer
6. PREG cat B
7. Poisoning=
n/v, confusion, drowsiness, confusion, liver TTP, ↓ BP,
cardiac arrythmias, jaundice, acute hepatic or renal
failure, all occur in ≤ 24 hours
8. Death d/t liver necrosis and renal failure may occur
9. TX gastric lavage withing 4 hours
Quiz: Ibuprofen (motrin)
What should you remember?
o
o
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, 4
Ans: 1. take with food, stay upright 15-30 min
2. block production prostaglandins (↓ BF kidney)
3. 3 or more doses/day, 5 x's/wk = rebound HA & pain
4. reversibly inhibit platelet aggregation, less and of shorter duration than
aspirin
5. Preg Cat C...D ≥ 30 wk gestation
6. Do NOT combo with other NSAIDs
7. LABs: LFTs, Renal Fx, CBC
8. 2nd line TX arthritis
Quiz: Naproxen Sodium (aleve)
What should you know?
o
o
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