question/answer graded A+ 2024/2025
What are cells' point of actions - ✔️✔️To send chemical messaged by means of
hormones
Target cells or end organs point of action - ✔️✔️Receive the chemical messages
How does the endocrine control the metabolic processes - ✔️✔️- Energy
- How we grow
- Deal with stress
- Sexual reproduction
The endocrine system consists of three components: - ✔️✔️(1) the cells, which send
chemical messages by means of hormones; (2) the target cells, or end organs, which
receive the chemical messages; and (3) the environment through which the chemicals
are transported (blood, lymph, extracellular fluids) from the sites of synthesis to the sites
of cellular action.
What is the endocrines one master gland? - ✔️✔️Pituitary gland
___________ is defined clinically as the loss of all anterior pituitary hormones, leaving
only posterior function intact - ✔️✔️Panhypopituitarism
Clinical manifestations of Panhypopituitarism: growth. Thyroid stimulating, Gonatropins,
adrenocorticotropic, antidiuretic, melanocytes-stimulating hormone (Symptoms related
to these hormones) - ✔️✔️Growth Hormone
• Short stature but proportional height and weight
• Delayed epiphyseal closure
• Delayed bone age proportional to height
• Premature aging common in later life
• Increased insulin sensitivity
Thyroid-Stimulating Hormone
• Short stature with infantile proportions
• Dry, coarse skin; yellow discoloration, pallor
• Cold intolerance
• Constipation
• Somnolence
• Bradycardia
• Dyspnea on exertion
• Delayed dentition, loss of teeth
Gonadotropins
• Absence of sexual maturation or loss of secondary sexual characteristics
• Atrophy of genitalia, prostate gland, breasts
, • Amenorrhea without menopausal symptoms
• Decreased spermatogenesis
Adrenocorticotropic Hormone
• Severe anorexia, weight loss
• Hypoglycemia
• Hypotension
• Hyponatremia, hyperkalemia
• Adrenal apoplexy, especially in response to stress
• Circulatory collapse
Antidiuretic Hormone
• Polyuria
• Polydipsia
• Dehydration
Melanocyte-Stimulating Hormone
• Decreased pigmentation
T or F Children with panhypopituitarism should wear a medical alert bracelet or
necklace. - ✔️✔️True
_______________- is diminished or deficient secretion of one or more pituitary
hormones - ✔️✔️Hypopitutarism
Clinical manifestations of Hypopitutarism - ✔️✔️-Slowed growth curve after first year
-Appear overweight due to stunted height
-Delayed sexual development
T or F if Hypopituitarism is gone without treatment the Childs permanent height will
remain the same - ✔️✔️True
•Consequences depend upon the degree of dysfunction of hypopitutarism - ✔️✔️-
Gonadotropin deficiency
-Growth hormone (GH) deficiency
-Thyroid-stimulating hormone (TSH) deficiency
-Corticotropin deficiency
What is the growth chart we use in Canada - ✔️✔️WHO
Definite diagnosis of hypopitutarism - ✔️✔️- Absent or definitive growth hormone levels
- Tests to look at bone age/ Tumours
Hypopituitarism therapeutic managment - ✔️✔️•Treatment is directed toward correction of
the underlying disease process.
Replacement with GH is successful in 80% of affected children.
•Nursing care for hypopituitarism - ✔️✔️-Identify and assist with the diagnosis.