NBDE Part I UPDATED Exam Questions
and CORRECT Answers
Fungi - CORRECT ANSWER - Organisms that exhibit dimorphism and grow on
Sabouraud's medium (low pH)
Sabouraud agar - CORRECT ANSWER - Type of agar used for most fungi?
Trichophyton - CORRECT ANSWER - Organism that causes athlete's foot (tinea pedis)
Trichophyton - CORRECT ANSWER - Which fungal infection leads to superficial skin
disease?
Epidermophyton & microsporum - CORRECT ANSWER - What organisms cause
dermatophytosis?
Aspergillus - CORRECT ANSWER - Alfatoxin is produced by what fungus?
Intracellular parasite - CORRECT ANSWER - Cell immunity is most important for?
Cryptococcus - CORRECT ANSWER - Which fungus causes cerebral/brain infarct? May
spread into the meninges and cause Cryptococcal Meningitis
Aspergillus - CORRECT ANSWER - Causes "fungus ball" in the lungs causing pulmonary
infection in people with AIDS or have undergone organ transplant
Mucormycosis - CORRECT ANSWER - Found in blood vessels (endothelium) and is
often related to diabetic patients; results in black, dead tissue in the nasal cavity and blocks the
blood supply to the brain
,Histoplasmosis - CORRECT ANSWER - What fungus can be seen as an intracellular
organism?
Histoplasmosis - CORRECT ANSWER - Disseminated fungi; yeast in macrophages,
bird/bat droppings, infection via respiratory droplets - different that rest of fungi
Histoplasmosis - CORRECT ANSWER - Which pathogen causes granulomatous lesion in
lungs resembling TB?
Gonorrhea - CORRECT ANSWER - Which of the following doesn't give you granulomas?
-Histoplasmosis
-Gonorrhea
-M. tuberculosis
-Tertiary syphilis
Histoplasmosis - CORRECT ANSWER - Which fungi does NOT cause a mucosal or
epidermal rash?
Histoplasma capsulatum - CORRECT ANSWER - Fungi associated with avian/bird?
D. Cryptococcosis - CORRECT ANSWER - Most common cause of fungal meningitis?
Mycelium (mold) or yeast - CORRECT ANSWER - What is dimorphism in fungus?
Aspergillus, blastomycosis, histoplasma, coccidioides, and cryptococcus neoformans -
CORRECT ANSWER - Fungal organisms found in the soil?
Histoplasma capsulatum, blastomyces dermatitidis, coccioides immitis, sporothrix shenckii,
candidas albicans - CORRECT ANSWER - Which fungus are dimorphic?
,Bacterial infection - CORRECT ANSWER - Pt has swelling of submandibular, tenderness.
Pt is alcoholic. Radiographic-mass radiopaque (sialolith) - circumscribed, 1 cm X 1 cm, what is
the reason for swelling?
Conjugation - CORRECT ANSWER - Best method for bacteria to replicate and transfer
most genetic information?
Transformation - CORRECT ANSWER - Bacteria takes up extracellular donor DNA
Transduction - CORRECT ANSWER - Donor DNA packed into virus (bacteriophage) that
infects the bacteria
Conjugation - CORRECT ANSWER - Plasmid DNA transfer
Attachment and adherence to host cells - CORRECT ANSWER - Action of the pilli in
organisms pathogenicity
Staph has catalase which gets rid of H2O2 - CORRECT ANSWER - Difference between
staph and strep?
Histoplasmosis - CORRECT ANSWER - Which fungi does NOT cause a mucosal or
epidermal rash?
Bacterial infection - CORRECT ANSWER - Pt has swelling of submandibular, tenderness.
Pt is an alcoholic. Radiographic mass radiopaque (sialolith) circumscribed, 1 cm x 1 cm, what is
the reason for swelling?
Conjugation - CORRECT ANSWER - Best method for bacteria to replicate & transfer
most genetic information?
, Transformation - CORRECT ANSWER - Bacteria takes up extracellular donor DNA
Transduction - CORRECT ANSWER - Donor DNA packed into virus (bacteriophage) that
infects the bacteria (1 step)
Conjugation - CORRECT ANSWER - Plasmid DNA transfer
Attachment and adherence to host - CORRECT ANSWER - Action of pilli in organisms
pathogenicity?
Staph has a catalase enzyme that gets rid of H2O2 - CORRECT ANSWER - Difference
between staph and strep?
Lancefield grouping - CORRECT ANSWER - Serotype classification determined by carb
composition of cell wall (that is, describing specific carbohydrates present on the bacterial cell
wall)
Protein production (translation) - CORRECT ANSWER - Streptomycin inhibits...
Enterotoxin - CORRECT ANSWER - What aspect of staph is responsible for food
poisoning?
Produces enzyme that breaks down penicillin, beta lactamase ring - CORRECT
ANSWER - MOA of s. aureus for drug resistance
S. aureus - CORRECT ANSWER - What bacteria causes endocarditis in IV drug users?
Streptococcus viridian (alpha-hemolytic strep) - CORRECT ANSWER - Most common
type of endocarditis?
and CORRECT Answers
Fungi - CORRECT ANSWER - Organisms that exhibit dimorphism and grow on
Sabouraud's medium (low pH)
Sabouraud agar - CORRECT ANSWER - Type of agar used for most fungi?
Trichophyton - CORRECT ANSWER - Organism that causes athlete's foot (tinea pedis)
Trichophyton - CORRECT ANSWER - Which fungal infection leads to superficial skin
disease?
Epidermophyton & microsporum - CORRECT ANSWER - What organisms cause
dermatophytosis?
Aspergillus - CORRECT ANSWER - Alfatoxin is produced by what fungus?
Intracellular parasite - CORRECT ANSWER - Cell immunity is most important for?
Cryptococcus - CORRECT ANSWER - Which fungus causes cerebral/brain infarct? May
spread into the meninges and cause Cryptococcal Meningitis
Aspergillus - CORRECT ANSWER - Causes "fungus ball" in the lungs causing pulmonary
infection in people with AIDS or have undergone organ transplant
Mucormycosis - CORRECT ANSWER - Found in blood vessels (endothelium) and is
often related to diabetic patients; results in black, dead tissue in the nasal cavity and blocks the
blood supply to the brain
,Histoplasmosis - CORRECT ANSWER - What fungus can be seen as an intracellular
organism?
Histoplasmosis - CORRECT ANSWER - Disseminated fungi; yeast in macrophages,
bird/bat droppings, infection via respiratory droplets - different that rest of fungi
Histoplasmosis - CORRECT ANSWER - Which pathogen causes granulomatous lesion in
lungs resembling TB?
Gonorrhea - CORRECT ANSWER - Which of the following doesn't give you granulomas?
-Histoplasmosis
-Gonorrhea
-M. tuberculosis
-Tertiary syphilis
Histoplasmosis - CORRECT ANSWER - Which fungi does NOT cause a mucosal or
epidermal rash?
Histoplasma capsulatum - CORRECT ANSWER - Fungi associated with avian/bird?
D. Cryptococcosis - CORRECT ANSWER - Most common cause of fungal meningitis?
Mycelium (mold) or yeast - CORRECT ANSWER - What is dimorphism in fungus?
Aspergillus, blastomycosis, histoplasma, coccidioides, and cryptococcus neoformans -
CORRECT ANSWER - Fungal organisms found in the soil?
Histoplasma capsulatum, blastomyces dermatitidis, coccioides immitis, sporothrix shenckii,
candidas albicans - CORRECT ANSWER - Which fungus are dimorphic?
,Bacterial infection - CORRECT ANSWER - Pt has swelling of submandibular, tenderness.
Pt is alcoholic. Radiographic-mass radiopaque (sialolith) - circumscribed, 1 cm X 1 cm, what is
the reason for swelling?
Conjugation - CORRECT ANSWER - Best method for bacteria to replicate and transfer
most genetic information?
Transformation - CORRECT ANSWER - Bacteria takes up extracellular donor DNA
Transduction - CORRECT ANSWER - Donor DNA packed into virus (bacteriophage) that
infects the bacteria
Conjugation - CORRECT ANSWER - Plasmid DNA transfer
Attachment and adherence to host cells - CORRECT ANSWER - Action of the pilli in
organisms pathogenicity
Staph has catalase which gets rid of H2O2 - CORRECT ANSWER - Difference between
staph and strep?
Histoplasmosis - CORRECT ANSWER - Which fungi does NOT cause a mucosal or
epidermal rash?
Bacterial infection - CORRECT ANSWER - Pt has swelling of submandibular, tenderness.
Pt is an alcoholic. Radiographic mass radiopaque (sialolith) circumscribed, 1 cm x 1 cm, what is
the reason for swelling?
Conjugation - CORRECT ANSWER - Best method for bacteria to replicate & transfer
most genetic information?
, Transformation - CORRECT ANSWER - Bacteria takes up extracellular donor DNA
Transduction - CORRECT ANSWER - Donor DNA packed into virus (bacteriophage) that
infects the bacteria (1 step)
Conjugation - CORRECT ANSWER - Plasmid DNA transfer
Attachment and adherence to host - CORRECT ANSWER - Action of pilli in organisms
pathogenicity?
Staph has a catalase enzyme that gets rid of H2O2 - CORRECT ANSWER - Difference
between staph and strep?
Lancefield grouping - CORRECT ANSWER - Serotype classification determined by carb
composition of cell wall (that is, describing specific carbohydrates present on the bacterial cell
wall)
Protein production (translation) - CORRECT ANSWER - Streptomycin inhibits...
Enterotoxin - CORRECT ANSWER - What aspect of staph is responsible for food
poisoning?
Produces enzyme that breaks down penicillin, beta lactamase ring - CORRECT
ANSWER - MOA of s. aureus for drug resistance
S. aureus - CORRECT ANSWER - What bacteria causes endocarditis in IV drug users?
Streptococcus viridian (alpha-hemolytic strep) - CORRECT ANSWER - Most common
type of endocarditis?
