Lippincott’s
Illustrated Review of
Pharmacology
Stanley Zaslau, MD
Professor and Chief, Division of Urology
Urology Residency Program Director
Course Director, Urology Rotation
West Virginia University
Morgantown, West Virginia
, TEST BANK FOR ; Q & A Review of
Pharmacology with Detailed Rationales
Guaranteed Pass Graded A+
Contents
Preface ............................................................................................................................................................................................ iii
Acknowledgments ............................................................................................................................................................................v
Chapter 1 Principles of Pharmacology ........................................................................................................................................1
Chapter 2 Principles of Neuropharmacology .............................................................................................................................35
Chapter 3 Cardiovascular Pharmacology ...................................................................................................................................81
Chapter 4 Endocrine Pharmacology ........................................................................................................................................ 123
Chapter 5 Drugs Affecting Other Systems (Including GI and Pulmonary).............................................................................. 159
Chapter 6 Chemotherapeutic Drugs ........................................................................................................................................ 201
Chapter 7 Inflammation, Immune Pharmacology, and Toxicology ........................................................................................ 247
Index ............................................................................................................................................................................................ 294
, QUESTIONS 4 A 27-year-old female with vulvovaginal candidiasis is
given a one-time 100 mg dose of oral fluconazole. She
Select the single best answer. has no other pertinent medical problems and takes
no prescription medications. Administration of the
1 A 79-year-old man with end-stage Alzheimer’s disease
medication results in a peak plasma concentration
and dysphagia is taking multiple medications. Physical
of 20 mg/mL. What is the apparent volume of drug
examination reveals xerostomia and a limited gag
distribution?
reflex. Which of the following routes of medication
administration would provide the lowest serum drug (A) 0.5 L
concentration? (B) 1 L
(A) Enteral (C) 3 L
(B) Intramuscular (D) 5 L
(C) Intrathecal (E) 50 L
(D) Intravenous
5 A 48-year-old-man with end-stage liver disease is hos-
(E) Transdermal
pitalized on the intensive care unit. Review of his
blood work reveals elevated liver function tests to five
2 A 28-year-old man with seborrheic dermatitis is pre-
times the normal rate. The patient is receiving multi-
scribed a topical corticosteroid crème by his derma-
ple intravenous medications. Which of the following
tologist in hopes of alleviating the chronic rash and
medications is likely to be therapeutic for this patient?
erythema on the cheeks. Which of the following steps
is most critical to achieve a therapeutic drug concen- (A) Epinephrine
tration in plasma? (B) Erythromycin
(A) Absorption (C) Nifedipine
(B) Distribution (D) Rifampin
(C) Elimination (E) Verapamil
(D) Glycosylation
6 A 29-year-old man presents to his primary care physi-
(E) Metabolism
cian complaining of dysuria, urgency, and painful
ejaculation. The patient has a past medical history of
3 A 31-year-old man is brought to the emergency de-
allergic rhinitis. Physical examination reveals a tender
partment complaining of dyspnea. He has a history of
prostate. The patient is given a prescription of sulfa-
asthma and has had multiple asthma attacks requiring
methoxazole to be taken daily (q 12 h) for 30 days.
intubation for airway maintenance. He is noncompli-
The half-life is 12 h. How long will it take for the
ant with his medications prescribed for this condition.
medication to reach 90% of its final steady state level?
Physical examination reveals a young man in acute
distress. His room air oxygen saturation is 87%. In (A) 10 h
addition to administration of oxygen, immediate drug (B) 20 h
administration of albuterol should be administered by (C) 30 h
which of the following routes? (D) 40 h
(A) Inhalation (E) 50 h
(B) Intranasal puff metered dose
(C) Subcutaneous
(D) Sublingual
(E) Topical
1
Illustrated Review of
Pharmacology
Stanley Zaslau, MD
Professor and Chief, Division of Urology
Urology Residency Program Director
Course Director, Urology Rotation
West Virginia University
Morgantown, West Virginia
, TEST BANK FOR ; Q & A Review of
Pharmacology with Detailed Rationales
Guaranteed Pass Graded A+
Contents
Preface ............................................................................................................................................................................................ iii
Acknowledgments ............................................................................................................................................................................v
Chapter 1 Principles of Pharmacology ........................................................................................................................................1
Chapter 2 Principles of Neuropharmacology .............................................................................................................................35
Chapter 3 Cardiovascular Pharmacology ...................................................................................................................................81
Chapter 4 Endocrine Pharmacology ........................................................................................................................................ 123
Chapter 5 Drugs Affecting Other Systems (Including GI and Pulmonary).............................................................................. 159
Chapter 6 Chemotherapeutic Drugs ........................................................................................................................................ 201
Chapter 7 Inflammation, Immune Pharmacology, and Toxicology ........................................................................................ 247
Index ............................................................................................................................................................................................ 294
, QUESTIONS 4 A 27-year-old female with vulvovaginal candidiasis is
given a one-time 100 mg dose of oral fluconazole. She
Select the single best answer. has no other pertinent medical problems and takes
no prescription medications. Administration of the
1 A 79-year-old man with end-stage Alzheimer’s disease
medication results in a peak plasma concentration
and dysphagia is taking multiple medications. Physical
of 20 mg/mL. What is the apparent volume of drug
examination reveals xerostomia and a limited gag
distribution?
reflex. Which of the following routes of medication
administration would provide the lowest serum drug (A) 0.5 L
concentration? (B) 1 L
(A) Enteral (C) 3 L
(B) Intramuscular (D) 5 L
(C) Intrathecal (E) 50 L
(D) Intravenous
5 A 48-year-old-man with end-stage liver disease is hos-
(E) Transdermal
pitalized on the intensive care unit. Review of his
blood work reveals elevated liver function tests to five
2 A 28-year-old man with seborrheic dermatitis is pre-
times the normal rate. The patient is receiving multi-
scribed a topical corticosteroid crème by his derma-
ple intravenous medications. Which of the following
tologist in hopes of alleviating the chronic rash and
medications is likely to be therapeutic for this patient?
erythema on the cheeks. Which of the following steps
is most critical to achieve a therapeutic drug concen- (A) Epinephrine
tration in plasma? (B) Erythromycin
(A) Absorption (C) Nifedipine
(B) Distribution (D) Rifampin
(C) Elimination (E) Verapamil
(D) Glycosylation
6 A 29-year-old man presents to his primary care physi-
(E) Metabolism
cian complaining of dysuria, urgency, and painful
ejaculation. The patient has a past medical history of
3 A 31-year-old man is brought to the emergency de-
allergic rhinitis. Physical examination reveals a tender
partment complaining of dyspnea. He has a history of
prostate. The patient is given a prescription of sulfa-
asthma and has had multiple asthma attacks requiring
methoxazole to be taken daily (q 12 h) for 30 days.
intubation for airway maintenance. He is noncompli-
The half-life is 12 h. How long will it take for the
ant with his medications prescribed for this condition.
medication to reach 90% of its final steady state level?
Physical examination reveals a young man in acute
distress. His room air oxygen saturation is 87%. In (A) 10 h
addition to administration of oxygen, immediate drug (B) 20 h
administration of albuterol should be administered by (C) 30 h
which of the following routes? (D) 40 h
(A) Inhalation (E) 50 h
(B) Intranasal puff metered dose
(C) Subcutaneous
(D) Sublingual
(E) Topical
1
