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Summary Biological membranes

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An easy to understand summary of biological membranes, including their functions, structures, and compositions, which will help you to better understand the topic and prepare for exams.

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Function Structure and Composition of Membranes

Membranes are complex lipid-based structures that form pliable sheets.

They are composed of a variety of lipids and proteins.

Membranes define the external boundaries of cells and control molecular traffic into and
out of the cell.

They selectively import polar solutes like nutrients and selectively export waste and toxins.

In eukaryotes, membranes divide the internal space into compartments (organelles) to
separate energy-producing reactions from energy-consuming ones and keep proteolytic
enzymes away from important cellular proteins.

Membranes are flexible and self-sealing, enabling membrane fusion.

Membranes retain metabolites and ions within the cell.

They sense external signals and transmit information into the cell.

Membranes produce and transmit nerve signals.

They store energy as a proton gradient to support the synthesis of ATP.

Membrane proteins act as transporters, receptors, adhesion sites, and recognition sites.

Three major structures are observed: micelles, bilayers, and liposomes.

Micelles form in the solution of amphipathic molecules with larger, more polar head than
tail.

Micelles are composed of a few dozen to a few thousand lipid molecules and aggregate
based on concentration.

Bilayers (membranes) consist of two leaflets of lipid monolayers.

Liposomes are small bilayers that spontaneously seal into spherical vesicles and can
contain artificially inserted proteins.

Liposomes are useful artificial carriers of molecules and can fuse with cell membranes or
with each other.

Membranes are sheet-like flexible structures, 3-10 nm thick.

They are composed of two leaflets of lipids (bilayer) and form spontaneously in aqueous
solutions.

Membranes are impermeable to most polar or charged solutes but permeable to small,
hydrophobic solutes.

Protein molecules span the lipid bilayer.

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