CLAYTON'S BASIC PHARMACOLOGY FOR
NURSES: CHAPTER 2 EXAM PREP QUESTIONS
WITH COMPLETE SOLUTIONS
drugs do not create new responses but rather - ANS-alter existing physiologic activity in several different
ways
specific sites which the drug usually forms chemical bonds with - ANS-receptors
a drug only forms a bond with a receptor if: - ANS-- the drug and the receptor have similar shapes
- the drug has a chemical affinity for the receptor
the study of the interactions between drugs and their receptors and the series of events that result in a
pharmacologic response - ANS-pharmacodynamics
T/F: the better the fit between the receptor and the drug molecule the better the response of the drug -
ANS-T
drugs that interact with a receptor to stimulate a response are known as - ANS-agonists
drugs that attach to a receptor but do not stimulate a response - ANS-antagonists
drugs that interact with a receptor to stimulate a response but inhibit other responses - ANS-partial
agonists
3 routes of drug administration: - ANS-- enteral
- parenteral
- percutaneous
when using the _______________ route, the drug is administered directly into the GI tract by oral,
rectal, or nasogastric route - ANS-enteral
when using the _________________ route, the drug bypasses the GI tract with the use of subcutaneous,
intramuscular, or intravenous injection - ANS-parenteral
when using the ___________________ route, the drug is absorbed through the skin and mucous
membranes - ANS-percutaneous
, after administration, all drugs go through 5 stages: - ANS-- liberation
- absorption
- distribution
- metabolism
- excretion
the study of what the body does to the drug - ANS-pharmacokinetics
release of a drug from the dosage form to be dissolved in body fluids for absorption - ANS-liberation
liberation of a drug within the body can be manipulated by: - ANS-- pharmaceutical dosage form used
(e.g. solution, suspension, capsule, tablet)
- administering the drug with or without food and water in the patient's stomach
the process whereby a drug is transferred from its site of entry into the body to the circulating fluids of
the body for distribution around the body - ANS-absorption
the rate at which a drug is absorbed depends on: - ANS-- route of administration
- blood flow through the tissue where the drug is administered
- solubility of the drug
the rate of absorption when a drug is administered by a parenteral route depends on the - ANS-rate of
blood flow through the tissues
absorption of a drug is slowest when administered this way - ANS-subcutaneous injection
T/F: after a drug enters a patient's bloodstream, it is still retrievable - ANS-F
the absorption of topical drugs that have been applied to the skin can be influenced by: - ANS-- drug
concentration
- length of contact time
- size of the affected area
- thickness of the skin surface
- hydration of tissue
- degree of skin disruption
when drugs are inhaled, their absorption can be influenced by: - ANS-- depth of the patient's respiration
- fineness of the droplet particles
- available surface area of the patient's mucous membranes
- contact time
- hydration state
- blood supply to area
- concentration of the drug itself
refers to the ways in which a drug is transported throughout the body by the circulating body fluids to
the sites of action or to the receptors that the drug affects - ANS-distribution
NURSES: CHAPTER 2 EXAM PREP QUESTIONS
WITH COMPLETE SOLUTIONS
drugs do not create new responses but rather - ANS-alter existing physiologic activity in several different
ways
specific sites which the drug usually forms chemical bonds with - ANS-receptors
a drug only forms a bond with a receptor if: - ANS-- the drug and the receptor have similar shapes
- the drug has a chemical affinity for the receptor
the study of the interactions between drugs and their receptors and the series of events that result in a
pharmacologic response - ANS-pharmacodynamics
T/F: the better the fit between the receptor and the drug molecule the better the response of the drug -
ANS-T
drugs that interact with a receptor to stimulate a response are known as - ANS-agonists
drugs that attach to a receptor but do not stimulate a response - ANS-antagonists
drugs that interact with a receptor to stimulate a response but inhibit other responses - ANS-partial
agonists
3 routes of drug administration: - ANS-- enteral
- parenteral
- percutaneous
when using the _______________ route, the drug is administered directly into the GI tract by oral,
rectal, or nasogastric route - ANS-enteral
when using the _________________ route, the drug bypasses the GI tract with the use of subcutaneous,
intramuscular, or intravenous injection - ANS-parenteral
when using the ___________________ route, the drug is absorbed through the skin and mucous
membranes - ANS-percutaneous
, after administration, all drugs go through 5 stages: - ANS-- liberation
- absorption
- distribution
- metabolism
- excretion
the study of what the body does to the drug - ANS-pharmacokinetics
release of a drug from the dosage form to be dissolved in body fluids for absorption - ANS-liberation
liberation of a drug within the body can be manipulated by: - ANS-- pharmaceutical dosage form used
(e.g. solution, suspension, capsule, tablet)
- administering the drug with or without food and water in the patient's stomach
the process whereby a drug is transferred from its site of entry into the body to the circulating fluids of
the body for distribution around the body - ANS-absorption
the rate at which a drug is absorbed depends on: - ANS-- route of administration
- blood flow through the tissue where the drug is administered
- solubility of the drug
the rate of absorption when a drug is administered by a parenteral route depends on the - ANS-rate of
blood flow through the tissues
absorption of a drug is slowest when administered this way - ANS-subcutaneous injection
T/F: after a drug enters a patient's bloodstream, it is still retrievable - ANS-F
the absorption of topical drugs that have been applied to the skin can be influenced by: - ANS-- drug
concentration
- length of contact time
- size of the affected area
- thickness of the skin surface
- hydration of tissue
- degree of skin disruption
when drugs are inhaled, their absorption can be influenced by: - ANS-- depth of the patient's respiration
- fineness of the droplet particles
- available surface area of the patient's mucous membranes
- contact time
- hydration state
- blood supply to area
- concentration of the drug itself
refers to the ways in which a drug is transported throughout the body by the circulating body fluids to
the sites of action or to the receptors that the drug affects - ANS-distribution
