Bushong: Radiologic Science For Technologists: Physics, Biology, And Protection, 8Th Edition

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BUSHONG: RADIOLOGIC SCIENCE FOR TECHNOLOGISTS:
PHYSICS, BIOLOGY, AND PROTECTION, 8TH EDITION
In vitro irradiation to macromolecules causes ___ damage to macromolecules.
a. repairable
b. reversible
c. irreversible
d. Both a and b.
d. Both a and b (repairable and reversible)
The most radiosensitive macromolecule is ___
a. protein
b. DNA
c. mRNA
d. tRNA
DNA
DNA is contained in the ___ of the cell nucleus
a. proteins
b. cytoplasm
c. chromosomes
d. RNA
chromosomes
A type of DNA damage that may not be reversible is ____
a. cross-linking.
b. base change or loss.
c. rung breakage.
d. severed side rail.
severed side rail
Radiation damage to DNA can result in ___
a. cell death.
b. malignant disease.
c. genetic changes.
d.Any of the above.
any of the above

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Molecular lesions of DNA are called ___
a. point mutations
b. broken side rails
c. cross-linking
d. rung breaks
point mutations
The principal radiation interaction within the human body is with____
a. DNA
b. macromolecules
c. water
d. RNA
water
The disassociation of water molecules following irradiation is termed ___
a. radiolysis
b. ionization
c. cross-linking
d. point mutation
radiolysis
When an atom of water is irradiated, it first dissociates into
a. two water atoms.
b. an ion pair.
c. free radicals.
d. hydrogen peroxide.
an ion pair
Two OH* free radicals can join to form ___ molcules.
a. organic free radical
b. hydroperoxyl
c. hydrogen peroxide
d. DNA
hydrogen peroxide
Free radicals can be damaging because they are
a. unstable.