Maryville University NURS615 Pharmacology Exam 4

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Maryville University NURS615 Pharmacology Exam 4

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2024/2025

Institution PHARM NURS 615

Course PHARM NURS 615

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Maryville University NURS615 Pharmacology Exam 4 What are examples of inhaled Short-acting Beta Agonists? (SABAs) Albuterol and levabuterol What is the MOA of inhaled beta agonists? To relax airway smooth muscle by increasing cyclic cAMP; dilation and opening of airway What is the use of inhaled beta agonists? Used in bronchospasm associated with: asthma, bronchitis, and COPD

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Maryville University NURS615
Pharmacology Exam 4

WhatAareAexamplesAofAinhaledAShort-actingABetaAAgonists?A(SABAs)A-
AANSWERAAlbuterolAandAlevabuterol

WhatAisAtheAMOAAofAinhaledAbetaAagonists?A-
AANSWERAToArelaxAairwayAsmoothAmuscleAbyAincreasingAcyclicAcAMP;AdilationAandAopeningAofAairwa
y

WhatAisAtheAuseAofAinhaledAbetaAagonists?A-
AANSWERAUsedAinAbronchospasmAassociatedAwith:Aasthma,Abronchitis,AandACOPD

WhenAareASABAsAusedA(albuterolAandAlevabuterol)?A-AANSWERAForAreliefAofAACUTEAasthmaAattacks

IsAalbuterolAapprovedAinAchildrenAunderA4?A-AANSWERAYes.

HowAdoAbeta-2AagonistsAaffectAcalcium?A-
AANSWERATheyAopenAlargeAconductionsAinAcalciumAactivatedApotassiumAchannelsA=AhyperpolarizedA
airwayAsmoothAmuscleAcells

1.AdecreasedAintracellularAcalcium

2.AincreasedApotassiumAconcentration

3.AdecreasedAmyocleynaseAactivityA=AsmoothAmuscleArelaxationAandAbronchodilation

WhatAareAexamplesAofAlong-actingAbetaAagonistsA(LABAs)?A-AANSWERAsalmetrolAandAformoterol

,WhatAareALABAsA(salmeterolAandAformoterol)AusedAfor?A-
AANSWERAUsedAforAPREVENTIONAorAlongAtermAtreatmentAofAasthma

NOTAforAacuteAattacks;AnotAfirstAlineAtreatment

CANNOTAbeAusedAalone

WhatApopulationAshouldALABAsANOTAbeAprescribedAin?A-AANSWERAAfricanAAmericans

WhatAisAspecialAaboutAtheAbetaA2AadrenergicAreceptorAgene?A-
AANSWERAThisAgeneAcausesALABAsAtoAworsenAasthmaAcontrol

WhoAisAmoreAlikelyAtoAhaveAtheAbetaA2AadrenergicAreceptorAgene?A-
AANSWERAAfricanAAmericans;AthisAgenotypeAisApresentAinA1/6thAofAtheAU.S.Apopulation

HowAdoesAtheAbetaA2AadrenergicAreceptorAgeneAcauseAworseningAasthmaAcontrolAwhenALABAsAareA
taken?A-
AANSWERAAsthmaticsAwithAthisAgeneAareAatAriskAforAdecreasedAairflowAandAworseningAasthmaAcontr
ol

WhatAareAadverseAeffectsAofAinhaledAbetaAagonists?A-AANSWERATachycardiaAandAtremors

WhatAisAtheAabsorptionAofAinhaledAbetaAagonists?A-AANSWERAVeryAlittleAsystemicAabsorption

WhatAareAexamplesAofAanticholinergics/antimuscarinicsAinAmaintenanceAtherapyAofACOPD?A-
AANSWERAipatropriumA(Atrovent)AandAtiotropriumA(Spiriva)

WhatAisAtheAMOAAofAanticholinergicsA(ipatropriumAandAtiotroprium)?A-
AANSWERATheyAblockAmuscarinicAreceptorsAdecreasingAtheAformationAofAcAMP

,CAUSESABRONCHODILATIONABY:A

1.AdecreasingAsmoothAmuscleAcontractionAofAlungsA(mainlyAonAM3Areceptors)

2.AdecreasesAmucousAsecretion

WhatAareAipatropriumAandAtiotropriumAusedAfor?A-AANSWERAMaintenanceAofACOPD

WhatAisAtiotropriumA(Spiriva)?A-AANSWERALONG-
ACTINGAbronchodilatorAforACOPD;AbetterAabsorbedAfromAlungAthanAipatropriumA(Atrovent)

WhatAisAipotropriumA(Atrovent)?A-AANSWERASHORT-ACTINGAbronchodilatorAforACOPD

WhatAbronchodilatorAisAtheAbestAchoiceAinApatientsAtakingApropranolol?A-
AANSWERAIpatropriumA(Atrovent)

WhatAareAtheAadverseAeffectsAofAipatropriumAandAtiotroprium?A-AANSWERAAnticholinergicA--
Acan'tAsee,Acan'tApee,Acan'tAspit,Acan'tAshit

WhatAareAexamplesAofAinhaledAcorticosteroids?A-
AANSWERAfluticasoneA(Flonase),AbudesonideA(Pulmicort),AbeclomethasoneAdiproprionateA(QVAR)

WhatAareAinhaledAcorticosteroidsAusedAfor?A-AANSWERALong-
termAtreatmentAofAasthmaA(severe,ApersistentAasthma);AtakenAeveryday

WhatAisAtheAabsorptionAofAinhaledAcorticosteroids?A-
AANSWERARapidAabsorptionAfromAlungAtissues;AgreaterAwithAuseAofAspacer

, WhatAeffectsAdoAinhaledAcorticosteroidsAhave?A-AANSWERAAnti-
inflammatoryAandAvasoconstrictorAeffectsA

HighlyAselectiveAagonistsAatAtheAglucocorticoidAreceptorAandAsomeAactivityAatAandrogen,Aestrogen,Aa
ndAcorticoidAreceptors

WhatAisAtheAMOAAofAinhaledAcorticosteroids?A-
AANSWERAINHIBITSAmastAcellAmigrationAtoAbronchialAtissues

WhatAisAtheAbioavailabilityAofAinhaledAcorticosteroids?A-
AANSWERALowAsystemicAbioavailability;AtheyAproduceAaAtopicalAeffectAonAtheAlungAwithoutAsignifican
tAsystemicAeffects

WhatAareAadverseAeffectsAofAinhaledAcorticosteroids?A-AANSWERA1.ACoughAuponAinhalation

2.AOralAcanadiasis/whiteAcoating--ApreventedAbyArinsingAmouthAwithAwaterAafterAinhalerAuse

3.ARareAallergicAreactions

4.ABurningAsmallAofAplastic,AunpleasantAtaste,AhoarsenessAorAnasalAcongestion,Apain,AHA,AorAvisualAc
hanges

HowAareAinhaledAcorticosteroidsAtoAbeAusedAandAtaken?A-
AANSWERAUsedAforAPREVENTIONAofAasthmaAexacerbationsA

ShouldAbeAtakenAtwiceAaAday,AeveryAday

WhatAisAtheAcorrectAorderAofAuseAofAcorticosteroidAandAbronchodilator?A-
AANSWERABRONCHODILATORAshouldAbeAusedAFIRSTAthenAinhaledAcorticosteroid

WhatAareAexamplesAofAmastAcellAstabilizersA(inhaledAanti-inflammatoryAagents)?A-
AANSWERACromolyn,Anedocromil

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