Maryville 615 Adv. Pharm Exam 2

Maryville 615 Adv. Pharm Exam 2

WhatSisSaSseizureSandSwhatScanSprecipitateSit?S-
SANSWERSASseizureSisStheSresultSofStheSabnormalSdischargeSofSneurons.SAnythingSthatSdisruptsStheSne
uronScanStriggerSabnormalSactivitySandSseizures.SHyperventilation,SsleepSdeprivation,SsensorySandSem
otionalSstress,SandShormonesSareSallSriskSfactors.



WhatSeducationSshouldSfamiliesSreceiveSregardingSseizureSmonitoring?S-SANSWERS--
SeizureSprevention:Ssleep,SexerciseSandSavoidanceSofSstressfulSsituations.SAdministerSmedsSsuchSasSan
ticonvulsants

--
PatientSsafety:SMonitorSszSfrequency,SdurationSandSseveritySinSadditionStoSchangesSinSmood,SsignsSofS
depression,SanxietySandSSuicidalSthoughts

--EnsureSptScarriesSmedicalSIDSbandSforSdisorder



WhatSeducationSisSimportantSregardingSanticonvulsants/antiepileptics?S-SANSWERS-
DoSnotSmissSaSdoseSorSabruptlySstop.SThisSmayScauseSanSincreaseSinSszSactivitySorSwithdrawalSszs



TellSmeSaboutSCarbamazepineS(Tegretol)?

-Class,Sindications,SMOA,ShalfSlifeSandScontraindications?S-SANSWERS--Class:SAnticonvulsants

--Indications:STxSepilepsy,SbipolarSaffectiveSdisorder,SaggressiveSbehaviorSandSneuralgias

--MOA:SSlowsSinfluxSofSNaSinSchannelsStoSdepressStransmissionSonStheSnucleusSventralis

--Absorbed:SOralSisSslowSbutSwellSabsorbed

--Half-Life:SaboutS30ShoursSinSaSsingleSdoseSandS15ShoursSifSgivenSrepeatedly

--Contraindications:ShxSofSbmSsuppression,SconcurrentSadminSw/SMAOIs



WhatSbloodSvaluesSshouldSbeSmonitoredSwithSCarbamazepine?S-SANSWERS-
RBC,SWBC,SandSpltsS(CBCSeveryS3-4Smonths)

,-HasSblackSboxSwarningStoScauseSbloodSdyscrasiasSwhichScausesSleukopeniaSandSthrombocytopenia

-Chem,SliverSfunctionSandSTSH



WhatSelseSdoesScarbamazepineShaveSaSblackSboxSwarningSfor?S-
SANSWERSDermatologicSreactionsSincludingSsteven'sSjohnsonSandStoxicSepidermalSnecrolysis




TellSmeSaboutSValproateS(ValproicSacid/depakote)?

-Class,Sindications,SMOASandScontraindications?S-SANSWERS--Class:Santiconvulsant

-Indications:STxSepilepsy,SbipolarSdisorder,Saggression,Sneuralgias

-MOA:SblocksSNaSchannels,SenhancesSGABAStoStheSbrainsSneurons

Contraindications:SdoSnotSuseSinSpregnancy,SitSisSaSteratogenSasSitScausesScongenitalSmalformations-
SneuralStubeSdefects


Education:SWomenSshouldSbeSusingSeffectiveScontraceptionSwhileStakingSvalproate



WhoSshouldSnotStakeSValproate?S-SANSWERSPregnantSWomen



TellSmeSaboutStopiramateS(Topamax)?

-Indications,SADRs,SwhatSshouldSbeSmonitored?S-SANSWERS-indications:SMonotherapySforSepilepsy

ADRs:Sataxia,Sdizziness,Ssomnolence,Sconfusion,Sdepression,SmoodSproblems

-
SMonitorSforSelectrolyteSimbalancesSasSmedScanScauseSdecreasedSserumSbicarbonateS(fromSincreasedS
renalSbicarbonate)SleadingStoSmetabolicSacidosis

-MonitorSserumSbicarbonate



WhatSisStheSmainSneurotransmitterSinvolvedSinSdepression?S-
SANSWERSSerotonin:SchemicalSinSbodySneededSforSnerveScellsSandSbrainStoSfunction.SAssociatedSwithS
angerSregulation,SbodyStemp.,Smood,Ssleep,SpainSmodulationSandSappetite.S

-providesShealing,Snourishing,SsatisfiedSfeelingSinStheSbody

, WhatScanSanSimbalanceSofSserotoninScause?S-SANSWERS-anxiety,SaggressionSandSappetite

-migraine,Spain,Spsychosis,Sobsessions,Semesis,SsexualSbehaviors,Ssleep,SsuicidalSthoughts



WhatSdoesSnorepinephrineSaffect?S-SANSWERSactivity,Salertness,SappetiteSandSsleepSpatterns



WhatSdoesSdopamineSaffect?S-
SANSWERSsleep,SsexualSbehavior,Saddictions,SanxietySlevel,SandSfeelingsSofSeuphoria




WhatSblackSboxSwarningsSdoSallSantidepressentSmedsShave?S-SANSWERS-
itSmaySgetSworseSbeforeSitSgetsSbetter.SIncreasedSriskSofSsuicideSinStheSfirstSfewSweeksSofStakingStheS
med



WhatSisSserotoninSsyndrome?SSymptoms?S-SANSWERSAnSaccumulationSofSserotoninSinStheSbody.S

-increasedSHR,SRunnySstomachSandSlossSofScontrolSofSbodySmovements.S

otherSS/
S:Snausea,Sshivering,Ssweating,Svasoconstriction,Shyperthermia,Shyperreflexia,Smycoclonus,Stremor,SHT
NSandSdeath.



WhatSisSaShypertensiveScrisis?S-
SANSWERSSevereSincreaseSinSbloodSpressureS(systolicSgreaterSthanS180,SdiastolicSgreaterSthanS120)Sth
atScanSdamageSbloodSvessels.



WhatSisSCHIPPSSSandSwhatSisSitScausesSby?S-SANSWERSSymptomsSofSHTNScrisis.S

-ChestStightness,Sheadache,SincreasedSHR,Spalpitations,SdilatedSpupils,SsweatingSandSstiffSneckS

-RequiresSimmediateSmanagementSandStheSpatientSshouldSremainSstandingSuntilScrisisSisSsolved