Maryville University Nursing 615 Exam 3
Review
LowdoseXcolchineANSWERX1.2XmgXatXfirstXsignXofXflare,XfollowedXbyX0.6XmgXoneXhourXlaterXforXaXtot
alXdoseXofX1.8Xmg.
High-doseXcolchineX-XANSWERX1.2XmgXfollowedXbyX0.6XmgXeveryX4-6XhoursXtotalingX4.8Xmg.
GoutX-
XANSWERXBUN,Xcreatinine,XandXcreatinineXclearanceXshouldXbeXmonitoredXinXtheXtreatmentXofXthisXd
isease
ColchineX-XANSWERXThisXmedicationXcanXcauseXsevereXdiarrhea,Xnausea,Xvomiting,XabdominalXpain
FebuxostatX(Uloric)X-
XANSWERXWhenXprescribingXthisXmedication,XpatientsXshouldXbeXtaughtXthatXgoutXmayXworsenXwithX
therapyXbeforeXitXimproves
CorticosteroidsX-
XANSWERXTheseXmedicationsXcanXcauseXtheXfollowingXadverseXeffectsXifXtakenXforXsixXmonthsXorXmor
e:XOsteoporosisXandXpoorXdiabeticXcontrol.XPatientsXshouldXreportXblack,XtarryXstoolsXorXabdominalXp
ain.
CorticosteroidsX-
XANSWERXTheseXmedicationsXshouldXbeXtaperedXtoXavoidXrecurrentXactivityXofXtheXunderlyingXdiseas
eXandXpossibleXcortisolXdeficiencyXresultingXfromXtheXhypothalamic-pituitary-
adrenalXaxisXsuppressionXduringXtheXperiodXofXsteroidXtherapy.
, BlackXBoxXWarningXonXNSAIDSX-
XANSWERXIncreasedXriskXofXseriousXcardiovascularXthromboticXevents,XsuchXasXmyocardialXinfarctionX
andXstroke.XTheseXmedicationsXcanXalsoXcauseXseriousXGIXeventsXsuchXasXbleeding,XulcerationXorXperf
orationXofXstomachXorXintestines,XwhichXcanXbeXfatal.
PainXmanagementX-
XANSWERXWhenXtreatingXthisXcommonXissue,XitXisXrecommendedXtoXbeginXwithXNSAIDSXandXworkXup
XfromXthereXasXneeded
IbuprofenX-
XANSWERXThisXmedicationXworksXbyXinhibitingXtheXCOXXenzymes;Xhowever,XtheXexactXmechanismXofX
actionXforXthisXparticularXmedicationXisXunknown.
AcetaminophenX-
XANSWERXAXseriousXadverseXeffectXrelatedXtoXthisXmedicationXisXreferredXtoXasX"-------------
Xpoisoning"
SymptomsXofXhypoglycemiaX-
XANSWERXDecreasedXLOC,Xhunger,Xdiaphoresis,Xweakness,XdizzinessXandXtachycardia
SymptomsXofXhyperglycemiaX-XANSWERXPolyuria,XpolydipsiaXandXpolyphagiaX(weightXloss)
SymptomsXofXDKAX-
XANSWERXKussmaul'sXrespiration,XketoneXodorXofXtheXbreathX(fruityXbreath),Xvomiting,Xdehydration,X
abdominalXpain,XandXneurologicXsymptomsXsuchXasXlethargy;XcanXprogressXtoXcomaXinXlaterXstagesXifX
leftXuntreated.
MetforminX-
XANSWERXThisXmedicationXdecreasesXhepaticXglucoseXoutputXinhibitingXgluconeogenesis.XItXalsoXincre
asesXinsulinXmediatedXglucoseXutilizationXinXperipheralXtissues.XThisXmedicationXdecreasesXintestinalXa
bsorptionXofXglucose.XThisXmedicationXmayXalsoXbeXusedXinXdiabeticsXtoXdecreaseXcholesterolXandXtri
glycerideXlevels.
Review
LowdoseXcolchineANSWERX1.2XmgXatXfirstXsignXofXflare,XfollowedXbyX0.6XmgXoneXhourXlaterXforXaXtot
alXdoseXofX1.8Xmg.
High-doseXcolchineX-XANSWERX1.2XmgXfollowedXbyX0.6XmgXeveryX4-6XhoursXtotalingX4.8Xmg.
GoutX-
XANSWERXBUN,Xcreatinine,XandXcreatinineXclearanceXshouldXbeXmonitoredXinXtheXtreatmentXofXthisXd
isease
ColchineX-XANSWERXThisXmedicationXcanXcauseXsevereXdiarrhea,Xnausea,Xvomiting,XabdominalXpain
FebuxostatX(Uloric)X-
XANSWERXWhenXprescribingXthisXmedication,XpatientsXshouldXbeXtaughtXthatXgoutXmayXworsenXwithX
therapyXbeforeXitXimproves
CorticosteroidsX-
XANSWERXTheseXmedicationsXcanXcauseXtheXfollowingXadverseXeffectsXifXtakenXforXsixXmonthsXorXmor
e:XOsteoporosisXandXpoorXdiabeticXcontrol.XPatientsXshouldXreportXblack,XtarryXstoolsXorXabdominalXp
ain.
CorticosteroidsX-
XANSWERXTheseXmedicationsXshouldXbeXtaperedXtoXavoidXrecurrentXactivityXofXtheXunderlyingXdiseas
eXandXpossibleXcortisolXdeficiencyXresultingXfromXtheXhypothalamic-pituitary-
adrenalXaxisXsuppressionXduringXtheXperiodXofXsteroidXtherapy.
, BlackXBoxXWarningXonXNSAIDSX-
XANSWERXIncreasedXriskXofXseriousXcardiovascularXthromboticXevents,XsuchXasXmyocardialXinfarctionX
andXstroke.XTheseXmedicationsXcanXalsoXcauseXseriousXGIXeventsXsuchXasXbleeding,XulcerationXorXperf
orationXofXstomachXorXintestines,XwhichXcanXbeXfatal.
PainXmanagementX-
XANSWERXWhenXtreatingXthisXcommonXissue,XitXisXrecommendedXtoXbeginXwithXNSAIDSXandXworkXup
XfromXthereXasXneeded
IbuprofenX-
XANSWERXThisXmedicationXworksXbyXinhibitingXtheXCOXXenzymes;Xhowever,XtheXexactXmechanismXofX
actionXforXthisXparticularXmedicationXisXunknown.
AcetaminophenX-
XANSWERXAXseriousXadverseXeffectXrelatedXtoXthisXmedicationXisXreferredXtoXasX"-------------
Xpoisoning"
SymptomsXofXhypoglycemiaX-
XANSWERXDecreasedXLOC,Xhunger,Xdiaphoresis,Xweakness,XdizzinessXandXtachycardia
SymptomsXofXhyperglycemiaX-XANSWERXPolyuria,XpolydipsiaXandXpolyphagiaX(weightXloss)
SymptomsXofXDKAX-
XANSWERXKussmaul'sXrespiration,XketoneXodorXofXtheXbreathX(fruityXbreath),Xvomiting,Xdehydration,X
abdominalXpain,XandXneurologicXsymptomsXsuchXasXlethargy;XcanXprogressXtoXcomaXinXlaterXstagesXifX
leftXuntreated.
MetforminX-
XANSWERXThisXmedicationXdecreasesXhepaticXglucoseXoutputXinhibitingXgluconeogenesis.XItXalsoXincre
asesXinsulinXmediatedXglucoseXutilizationXinXperipheralXtissues.XThisXmedicationXdecreasesXintestinalXa
bsorptionXofXglucose.XThisXmedicationXmayXalsoXbeXusedXinXdiabeticsXtoXdecreaseXcholesterolXandXtri
glycerideXlevels.
