Murphy Biochem Rutgers Exam 2 Questions and Answers 100% Pass

Murphy Biochem Rutgers Exam 2
Questions and Answers 100% Pass

Place the following reaction intermediates of the CAC in chronological order


i. malate ii. fumarate iii. succinyl CoA iv. citrate v. a-ketoglutarate - ✔✔iv, v, iii, ii, i


Oxalosuccinate is a transient intermediate formed during which of the following

reactions? - ✔✔isocitrate to a-ketoglutarate


FADH2 is a product of which of the following reactions? - ✔✔succinate to fumarate


NADH is produced in which of the following reactions? - ✔✔a-ketoglutarate to succinyl

CoA


Which of the following reactions can be described as anaplerotic? - ✔✔pyruvate + co2

to oxaloacetate


The enzymes that are unique to the glyoxylate cycle include ____________ -

✔✔isocitrate lyase


The regulated enzyme of the CAC include _________ - ✔✔a-ketoglutarate

dehydrogenase




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,The enzymes involved in citrate metabolism include all of the following except

________ - ✔✔malate synthase


Redox potential is best defined as - ✔✔the tendency of a species to gain or lose electrons


In order to determine the standard voltage of a reaction - ✔✔the standard cells must be

written as they occur in the reaction and the voltages are added


Which of the following reactions is an oxidation reaction?


a. NaOH + HCl -> NaCl + H2O


b. CH3COOH -> CH3COO- + H+


c. CH3CHO -> CH3CH2OH


d. CH3CH2OH -> CH3CHO


e. CH2=CH2 + H2O -> CH3CH2OH - ✔✔CH3CH2OH -> CH3CHO


Which of the following reactions has an oxidized product?


a. carboxylic acid -> aldehyde


b. R-SH + R-SH -> R-S-S-R


c. alcohol -> ketone


d. glutamate -> a-ketoglutarate


e. none of the above - ✔✔none of the above



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,In any redox reaction, an electron donor is - ✔✔the reducing agent


In an redox reaction, an electron acceptor is - ✔✔converted to an electron donor with

the gain of one or more electrons


Each turn of the CAC produces how many moles of CO2? - ✔✔2


Acetyl CoA that is consumed by the CAC is produced from which of the following

biochemical pathways?


a. glycolysis


b. fatty acid oxidation


c. purine catabolism


d. urea cycle


e. both A and B are correct - ✔✔both A and B are correct


Which of the following is the strongest reducing agent?


a. FADH2 (+ 0.22 V)


b. H2 (+ 0.424 V)


c. cytochrome a * Fe 2+ (-0.29 V)


d. lactate (+0.19 V)


e. H2O (-0.82 V) - ✔✔H2



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, Which of the following reacts with the acetyl-CoA to form citrate? - ✔✔oxaloacetate


The redox reaction in which succinate is converted to fumarate uses FAD rather than

NAD+ because? - ✔✔FAD is a stronger oxidizing agent than NAD+


Which of the following CAC enzymes are closely regulated?


a. citrate synthase


b. isocitrate dehydrogenase


c. a-ketoglutarate dehydrogenase


d. both A and B are correct


e. A, B, and C are all correct - ✔✔A, B, and C are all correct


Which of the following requires GDP? - ✔✔succinyl-CoA to succinate


How many oxidation steps are there in the CAC? - ✔✔4


Which of the following is a cofactor for the conversion of succinate to fumarate? -

✔✔FAD


Which of the following reactions involves a substrate level phosphorylation? -

✔✔succinyl-CoA to succinate


The carbon skeletons of which of the following can be incorporated directly into the

protein?




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