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Co- Solvents and Solvents
Created @October 24, 2024 9:15 PM
Class Molecules to Medicine
Importance of Solubility:
Drug= soluble in water and contain lipid based aspects
H bonding+ hydrophobic interactions affects molecule behaviour
Water actively involved in drug transport to action site
Oral administration of drug needs to dissolve in gastric fluid before
transportation to action site
Poor Solubility of Mebendazole:
Almost insoluble in water, 96% is ethanol and rest is methylene chloride
Absorption less than 10% in oral administration due to incomplete
absorption systemically
Treats gastrointestinal infestations of threadworm
Bulk Liquids:
Molecules distributed at random
Frequent collisions
Spaces between molecules provide fluidity
Molecules held together temporarily by intermolecular forces
Some molecules evaporate
Co- Solvents and Solvents 1
Co- Solvents and Solvents
Created @October 24, 2024 9:15 PM
Class Molecules to Medicine
Importance of Solubility:
Drug= soluble in water and contain lipid based aspects
H bonding+ hydrophobic interactions affects molecule behaviour
Water actively involved in drug transport to action site
Oral administration of drug needs to dissolve in gastric fluid before
transportation to action site
Poor Solubility of Mebendazole:
Almost insoluble in water, 96% is ethanol and rest is methylene chloride
Absorption less than 10% in oral administration due to incomplete
absorption systemically
Treats gastrointestinal infestations of threadworm
Bulk Liquids:
Molecules distributed at random
Frequent collisions
Spaces between molecules provide fluidity
Molecules held together temporarily by intermolecular forces
Some molecules evaporate
Co- Solvents and Solvents 1
