Summary Topic 6 Non Specific Defense

Non-Specific
Non specific immune response attacks all pathogens
despite antigens
S.I units




Skin

1
Physical barrier prevents pathogens >
-


waxy
- -


.




fibrous
-
> Keratin e
structure
protein >
-
secondary
rich
↳ Impenetrable
2
. Biological /commensall
species
- Skin
flora bacterial

↳ dont cause disease (non pathogen
compete will
man for
pathogens and resources
-


space
↳ better
adapted pathogens

3 .
Lipids fatty acids with antimicrobial properties
- oil
- sebum


Mouth
- >
lysozyme enzymes are
exocytosed from
cells
↳ break down all wall peptide links
↳ in tears


Stomach HC1 lower
pH-enzymes affected
- ->


denature
bonds and ionic bonds
↳
hydrogen
commensals
gut flora
-




Blood
clotting preventing
>
-
,
pathogens entering