Cystic Fibrosis
Mucus -
When there is excess water in the mucus
regulation
S.I units
. Sodium
1 ions are pumped out of the epithelial cell via basal
membrane into the tissue fluid vic active transport
.
Reduces concentration of sodium ions in .
cell
2
. Concentration
gradient formed between mucus and inside cell.
Facilitated
Sodium
diffusion of ions via a channel protein
in the apical membrane into the epithelial cell reduces ions
Concentration in the Mucus
. Positive
3 tissue
fluid. Electrical gradient
charge resides in the .
Chloride Cli down the
ions , move
gradient to the tissue
fluid
4. More
solute in the tissue fluid which decrease the water
potential in tissue fluid
. Vic Osmosis water
diffuses out
of the cell
down the concentration
gradient lowering the water potential
in the cell
3 .
Higher water potential in the mucus due to lower solutes
means via osmosis water
diffuses from murus into the
epithelial cell -
-
Mucus becomes more viscous
, S.I units
Mucus -
When there is excess water in the mucus
regulation
S.I units
. Sodium
1 ions are pumped out of the epithelial cell via basal
membrane into the tissue fluid vic active transport
.
Reduces concentration of sodium ions in .
cell
2
. Concentration
gradient formed between mucus and inside cell.
Facilitated
Sodium
diffusion of ions via a channel protein
in the apical membrane into the epithelial cell reduces ions
Concentration in the Mucus
. Positive
3 tissue
fluid. Electrical gradient
charge resides in the .
Chloride Cli down the
ions , move
gradient to the tissue
fluid
4. More
solute in the tissue fluid which decrease the water
potential in tissue fluid
. Vic Osmosis water
diffuses out
of the cell
down the concentration
gradient lowering the water potential
in the cell
3 .
Higher water potential in the mucus due to lower solutes
means via osmosis water
diffuses from murus into the
epithelial cell -
-
Mucus becomes more viscous
, S.I units
