Correct Answers.
Chemical name - Answer Describes the drug's chemical composition and molecular structure
Ex: (+/-)-2-(p-isobutylephenyl) propionic acid
Generic name - Answer Nonproprietary name
-Given by the United States Adopted Names Council
-Used in most official drug compendiums to list drugs
Ex: Ibuprofen
Trade name - Answer Proprietary name
-The drug has a registered trademark; use of the name is restricted by the drug's patent owner (usually
the manufacturer)
Ex: Motrin, others
____________ determines the rate of drug dissolution - Answer Dosage form
Drug dissolution - Answer dissolving of solid dosage forms and their absorption from the GI tract
Fastest drug absorption - Answer Oral disintegration, buccal tablets, oral soluable wafers
Slowest drug absorption - Answer Enteric-coated tablets
Drug absorption from fastest to slowest - Answer -Oral disintegration, buccal tablets, oral soluable
wafers
-Liquids, elixirs, and syrups
-Suspension solutions
-Powders
,-Capsules
-Tablets
-Coated tablets
-Enteric-coated tablets
Absorption - Answer Movement of a drug from its site of administration into the blood stream for
distribution to the tissues
Bioavailablitiy - Answer Extent of drug absorption
Medication routes - Answer -Enteral
-Parenteral
-Topical
Enteral - Answer (GI tract)
-orally vs sublingual and buccal routes, G tube
-First pass effect, variable absorption
Patenteral - Answer -Intravenous (IV)
-Intramuscular (IM)
Intravenous (IV) - Answer Rapid onset
Avoid first pass effect
IV: Nursing considerations - Answer Monitor drug
Check for compatibilities
Monitor IV site
Intramuscular (IM) - Answer Subcutaneously
,Topical - Answer Avoid first-pass effect, except rectal administration
-Transdermal
-Topical
Transdermal - Answer Deliver constant amount
Slower onset, prolong duration
Patent life - Answer Length of time from patent approval until patent expiration
-Normally 17 years in newly discovered drug molecule
Biosimilar - Answer Copy version of an already authorized biological product
-New category of the generic drug market
Therapeutic equivalence - Answer One drug in a class of several drugs is chosen as the preferred agent,
even though the drugs do not have the same active ingredients
-In place due to high cost of drugs
-Both drugs have same therapeutic effect on the body
Drug classification - Answer Drugs are grouped together based on their similar properties
-Can be classified by structure or therapeutic use
Three basic areas of pharmacology that describe the relationship between the dose of a drug and the
activity of that drug in treating the disorder - Answer Pharmaceutics
Pharmacokinetics
Pharmacodynamics
Pharmaceutics - Answer The study of how various drug forms influence the way in which the drug
affects the body
-Different drug dosage forms have different pharmaceutical properties
, Pharmacokinetics - Answer The study of what the body does to the drug
-Involves absorption, distribution, metabolism, and excretion
Pharmacodynamics - Answer The study of what the drug does to the body
-Involves drug-receptor relationships
Pharmacotherapeutics - Answer (Therapeutics)
Focuses on clinical use of drugs to prevent and treat diseases
-Defines the principles of drug actions
Phases of drug activity - Answer Administration
1. Pharmaceutical phase: Disintegration of dosage form; dissolution of drug in body
Drug available for absorption
2. Pharmacokinetic phase: Absorption, distribution, metabolism, excretion
Drug available for action
3. Pharmacodynamic phase: Drug-receptor interaction
Effect
Off-label prescribing - Answer Use of drugs for non-FDA-approved indications
Toxicology - Answer Study of adverse effects of drugs and other chemicals on living systems
Toxic effects - Answer Often an extension of a drug's therapeutic action.
Pharmacognosy - Answer The study of natural drug sources
(plants, animals, minerals)
Oral drugs - Answer May be in solid form: