PHARMACOLOGY NU150 EXAM 1
QUESTIONS WITH CORRECT ANSWERS
Evaluation of pt after uti anti-infective therapy: - answer---therapeutic effect is achieved
and symptoms are relieved
--adverse reactions are identified, reported to pcp and managed successfully
--pt and/or family verbalize and demonstrate understanding of the drug regimen
What is the study of drugs and their action on living organisms? - answer-pharmacology
What is the official name of a drug? - answer-generic name
Ex. Acetominophen
What is the selected name of a drug given by a specific company for marketing
purposes? - answer-trade name
Ex. Tylenol
What agency is responsible for the approval of new drugs in the united states? -
answer-fda (food and drug administration)
What agency polices drugs in the us? - answer-dea (drug enforcement agency)
Regulates drugs that have the potential for abuse. - answer-controlled substance act of
1970
What is a drug or substance that causes abnormal development of a fetus, leading to
deformities? - answer-teratogens
What are the 3 phases of drug activity in the body? - answer-pharmaceutic phase
Pharmacokinetic phase
Pharmacodynamic phase
The phase of drug activity in the body that includes the dissolution and breaking down
of the drug in the body? - answer-pharmaceutic phase
The phase of drug activity in the body that includes the activities w/ in the body after a
drug is administered? - answer-pharmacokinetic phase
The phase of drug activity in the body that includes the drug action and effect w/ in the
body. - answer-pharmacodynamic phase
Pharmacokinetic activity in the body involving biotransformation. - answer-the med is
metabolized in the liver
, Where are drugs excreted? - answer-majority through the kidneys
What activities in the body are included during the pharmacokinetic phase? - answer-
absorption
Distribution
Biotransformation
Excretion
Half-life
The time required for the body to eliminate 50% of the drug. Is important for the
frequency of dosing. - answer-half-life
Short half-life means ____________________ dosing. - answer-more frequent
Longer half-life means ____________________ dosing. - answer-less frequent
How many half lives does it take to eliminate 98% of a drug from the body? - answer-5-
6
Why do we have to use caution with the frequency of dosing in pt's w/ kidney or liver
disease? - answer-pt w/ liver disease will not be able to metabolize meds as normal and
accumulate a build up of a med, so they will get a med less often.
Pt w/ kidney disease cannot excrete med and will acquire a build up and be prescribed
less frequently
The desired effect or therapeutic effect of a drug. - answer-primary effect
All other effects other than the therapeutic/desired effect whether it is desired or not. -
answer-secondary effect
Drugs that bind w/ receptor to produce a therapeutic response. - answer-agonist
Partial binding = less response
Join w/ the receptor to prevent action of an agonist and prevents a pharmacological
effect. - answer-antagonist
What is an example of an antagonist? - answer-narcan blocks the effect of morphine;
used in reversing overdose of morphine
What is another name for side-effects? - answer-adverse reactions
Besides side-effect, what is another word for adverse reaction? - answer-
hypersensitivity reaction
Produces antibodies and causes an allergic reaction by the next dose. - answer-
antigen-antibody response
QUESTIONS WITH CORRECT ANSWERS
Evaluation of pt after uti anti-infective therapy: - answer---therapeutic effect is achieved
and symptoms are relieved
--adverse reactions are identified, reported to pcp and managed successfully
--pt and/or family verbalize and demonstrate understanding of the drug regimen
What is the study of drugs and their action on living organisms? - answer-pharmacology
What is the official name of a drug? - answer-generic name
Ex. Acetominophen
What is the selected name of a drug given by a specific company for marketing
purposes? - answer-trade name
Ex. Tylenol
What agency is responsible for the approval of new drugs in the united states? -
answer-fda (food and drug administration)
What agency polices drugs in the us? - answer-dea (drug enforcement agency)
Regulates drugs that have the potential for abuse. - answer-controlled substance act of
1970
What is a drug or substance that causes abnormal development of a fetus, leading to
deformities? - answer-teratogens
What are the 3 phases of drug activity in the body? - answer-pharmaceutic phase
Pharmacokinetic phase
Pharmacodynamic phase
The phase of drug activity in the body that includes the dissolution and breaking down
of the drug in the body? - answer-pharmaceutic phase
The phase of drug activity in the body that includes the activities w/ in the body after a
drug is administered? - answer-pharmacokinetic phase
The phase of drug activity in the body that includes the drug action and effect w/ in the
body. - answer-pharmacodynamic phase
Pharmacokinetic activity in the body involving biotransformation. - answer-the med is
metabolized in the liver
, Where are drugs excreted? - answer-majority through the kidneys
What activities in the body are included during the pharmacokinetic phase? - answer-
absorption
Distribution
Biotransformation
Excretion
Half-life
The time required for the body to eliminate 50% of the drug. Is important for the
frequency of dosing. - answer-half-life
Short half-life means ____________________ dosing. - answer-more frequent
Longer half-life means ____________________ dosing. - answer-less frequent
How many half lives does it take to eliminate 98% of a drug from the body? - answer-5-
6
Why do we have to use caution with the frequency of dosing in pt's w/ kidney or liver
disease? - answer-pt w/ liver disease will not be able to metabolize meds as normal and
accumulate a build up of a med, so they will get a med less often.
Pt w/ kidney disease cannot excrete med and will acquire a build up and be prescribed
less frequently
The desired effect or therapeutic effect of a drug. - answer-primary effect
All other effects other than the therapeutic/desired effect whether it is desired or not. -
answer-secondary effect
Drugs that bind w/ receptor to produce a therapeutic response. - answer-agonist
Partial binding = less response
Join w/ the receptor to prevent action of an agonist and prevents a pharmacological
effect. - answer-antagonist
What is an example of an antagonist? - answer-narcan blocks the effect of morphine;
used in reversing overdose of morphine
What is another name for side-effects? - answer-adverse reactions
Besides side-effect, what is another word for adverse reaction? - answer-
hypersensitivity reaction
Produces antibodies and causes an allergic reaction by the next dose. - answer-
antigen-antibody response