TEST BANK FOR CLAYTON’S BASIC PHARMACOLOGY FOR
NURSES 19TH EDITIONBY MICHELLE J. WILLIHNGANZ,
SAMUEL L. GUREVITZ, BRUCE CLAYTON COMPLETE
,Chapter0001:00Drug00Definitions,00Standards,00and00Information00Sources00Willi
hnganz:00Clayton’s00Basic00Pharmacology00for00Nurses,0019th00Edition
MULTIPLE00CHOIC
E
1. Which00name00identifies00a00drug00listed00by00the00US00
Food00and00Drug00Administration00(FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS:00 C
The00official00name00is00the0 0 name00under00which00a00drug
00is00listed00by00the00FDA.00The00brand00name,00or00tradema
rk,00is00the00name00given00to00a00drug00by00its00manufacture
r.00The00nonproprietary,00or00generic,00name00is00provided00
by00the00United00States00Adopted00Names00Council.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.009
OBJ:001NAT:00NCLEX00Client00Needs00Category:00Safe,00Effect
ive00Care00Environment00TOP:0 0 Nursing00Process00Step:00Assessment
CON:0
0Patient00Education
2. Which00source00contains00information00specific00to00nutritional00supplements?
a. USP00Dictionary00of00USAN00 &00International00Drug00Names
b. Natural00Medicines00Comprehensive00Database
c. United00States00Pharmacopoeia/National00Formulary00(USP00NF)
d. Drug00Interaction00Facts
ANS:00 C
United00States00Pharmacopoeia/National00Formulary00contains00information00specific00to00nut
ritional00supplements.00USP00Dictionary00of00USAN00&00International00Drug00Names00is00a00
compilation00of00drug00names,00pronunciation00guide,00and00possible00future00FDA00approved
00drugs;00it00does00not00include00nutritional00supplements.00 Natural00Medicines00Comprehens
ive00Database00contains
evidence-
based00information00on00herbal00medicines00and00herbal00combination00products;00it00does00not
00include00information00specific00to00nutritional00supplements.00Drug00Interaction00Facts00con
tains00comprehensive00information00on00drug00interaction00facts;00it00does00not00include00nutr
itional00supplements.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.004
OBJ:00300NAT:0 0 NCLEX00Client00Needs00Category:00Physiologi
cal00Integrity
TOP:0 0 Nursing00Process00Step:00Assessment CON:0 0 Nutrition00|00Patient00Education
3. Which00drug00reference00contains00drug00monographs00that00describe00all00drugs00in00a00therapeutic00cl
ass?
a. Drug00Facts00and00Comparisons
,Test00Bank00For00Clayton’s00Basic00Pharmacology00for00Nurses0019 3
th00Edition
b. Drug00Interaction00Facts
c. Handbook00on00Injectable00Drugs
d. Martindale—The00Complete00Drug00Reference
ANS:00 A
Drug00Facts00and00Comparisons00contains00drug00monographs00that00describe00all00
drugs00in00a00therapeutic00class.00Monographs00are00formatted00as00tables00to00allow00c
omparison00of00similar00products,00brand00names,00manufacturers,00cost00indices,00and
00available00dosage00forms00Online00version00is00available.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.00400Table001.2
OBJ:000000 3 NAT:0 0 NCLEX00Client00Needs00Category:00Physiological00Integrity
TOP:0 0 Nursing00Process00Step:00Assessment
CON:0 0 Safety00|00Patient00Education00|00Clinical00Judgment
4. Which00drug00reference00contains00monographs00about00 virtually00every00single-
entity00drug00available00in00the00United00States00and00describes00therapeutic00uses00of00drugs,
00including00approved00and00unapproved00uses?
a. Martindale:00The00Complete00Drug00Reference
b. AHFS00Drug00Information
c. Drug00 Reference
d. Drug00Facts00and00Comparisons
ANS:00 B
AHFS00Drug00Information00contains00monographs00about00virtually00every00single-
entity00drug00available00in00the00United00States00and00describes00therapeutic00uses00of00drugs,0
0 including00approved00and00unapproved00uses.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.00400Table001.2
OBJ:000000 3 NAT:0 0 NCLEX00Client00Needs00Category:00Physiological00Integrity
TOP:0 0 Nursing00Process00Step:00Planning CON:0 0 Safety00|00Patient00Education00|00Clinical00Judgment
5. Which00online00drug00reference00makes00available00to00healthcare00providers00and00the00
public00a00standard,00comprehensive,00up-to-
date00look00up00and00downloadable00resource00about00medicines?
a. American00Drug00Index
b. American00Hospital00Formulary
c. DailyMed
d. Drug00Reference
ANS:00 C
DailyMed00makes00available00to00healthcare00providers00and00the00public00a00standard,00com
prehensive,00up-to-
date00look00up00and00downloadable00resource00about00medicines.00The00American00Drug00Ind
ex00is00not00appropriate00for00patient00use.00The00American00Hospital00Formulary00is00not00ap
propriate00for00patient00 use.00The00drug00reference00 is00not00appropriate00for00patient00 use.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.00300|00p.004
OBJ:00300NAT:0 0 NCLEX00Client00Needs00Category:00Physiologi
cal00Integrity
TOP:0 0 Nursing00Process00Step:00Implementation
CON:0 0 Safety00|00Patient00Education00|00Clinical00Judgment
6. Which00legislation00authorizes00the00FDA00to00determine00the00safety00of00a00drug00before00its00marketi
ng?
a. Federal00Food,00Drug,00and00Cosmetic00Act00(1938)
b. Durham00Humphrey00Amendment00(1952)
, Test00Bank00For00Clayton’s00Basic00Pharmacology00for00Nurses0019 4
th00Edition
c. Controlled00Substances00Act00(1970)
d. Kefauver00Harris00Drug00Amendment00(1962)
ANS:00 A
The00Federal00Food,00Drug,00and00Cosmetic00Act00of00193800authorized00the00FDA00to00dete
rmine00the00safety00of00all00drugs00before00marketing.00Later00amendments00and00acts00helpe
d00tighten00FDA00control00and00ensure00drug00safety.00The00Durham00Humphrey00Amendme
nt00defines00the00kinds00of00drugs00that00cannot00be00used00safely00without00medical00supervi
sion00and00restricts00their00sale00to00prescription00by00a00licensed00practitioner.00The00Controll
ed00Substances00Act00addresses00only00controlled00substances00and00their00categorization.00The
00Kefauver00Harris00Drug00Amendment00ensures00drug00efficacy00and00greater00drug00safety.00
Drug00manufacturers00are00required00to00prove00to00the00FDA00the00effectiveness00of00their00
products00before00marketing00them.
DIF: Cognitive00Level:00Knowledge REF:00p.00500Table00l.3
OBJ:0 0 5
NAT:00NCLEX00Client00Needs00Category:00Physiological00I
ntegrity00TOP:0 0 Nursing00Process00Step:00Assessment
CON:0 0 Safety00|00Patient00Education00|00Evidence00|00Health00Care00Law
7. Which00classification00does00meperidine00(Demerol)00fall00under?
a. I
b. II
c. III
d. IV
ANS:00 B
Meperidine00(Demerol)00is00a00Schedule00II00drug;00it00has00a00high00potential00for00abuse00a
nd00may00lead00to00severe00psychological00and00physical00dependence.00Schedule00I00drugs00ha
ve00high00potential00for00abuse00and00no00recognized00medical00use.00Schedule00III00drugs00ha
ve00some00potential00for00abuse.00Use00may00lead00to00low00to00moderate00physical00depende
nce00or00high00psychological00dependence.00Schedule00IV00drugs00have00low00potential00for00
abuse.00Use00may00lead00to00limited00physical00or00psychological00dependence.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.0010
OBJ:00200NAT:0 0 NCLEX00Client00Needs00Category:00Safe,00Effe
ctive00Care00Environment
TOP:0 0 Nursing00Process00Step:00Assessment CON:0 0 Patient00Education00|00Addiction00|00Pain
8. Which00action00would00the00FDA00take00to00expedite00drug00development00 and00approval00for0
0an00outbreak00of00smallpox?
a. List00smallpox00as00a00health00orphan00disease.
b. Omit00the00preclinical00research00phase.
c. Extend00the00clinical00research00phase.
d. Fast00track00the00investigational00drug.
ANS:00 D
Once00the00Investigational00New00Drug00Application00has00been00approved,00the00drug00can0
0receive00highest00priority00within00the00agency,00which00is00called00fast00tracking.00A00small
pox00outbreak00would00become00a00priority00concern00in00the00world.00Orphan00diseases00are
00not00researched00in00a00priority00manner.00Preclinical00research00is00not00omitted.00Extendin
g00any00phase00of00the00research00would00mean00a00longer00time00to00develop00a00vaccine.00The
00FDA00must00ensure00that00all00phases00of00the00preclinical00and00clinical00research00phase00 ha
ve00been00completed00in00a00safe00manner.
DIF: Cognitive00Level:00Knowledge REF:000000p.007 OBJ:0 0 5
NURSES 19TH EDITIONBY MICHELLE J. WILLIHNGANZ,
SAMUEL L. GUREVITZ, BRUCE CLAYTON COMPLETE
,Chapter0001:00Drug00Definitions,00Standards,00and00Information00Sources00Willi
hnganz:00Clayton’s00Basic00Pharmacology00for00Nurses,0019th00Edition
MULTIPLE00CHOIC
E
1. Which00name00identifies00a00drug00listed00by00the00US00
Food00and00Drug00Administration00(FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS:00 C
The00official00name00is00the0 0 name00under00which00a00drug
00is00listed00by00the00FDA.00The00brand00name,00or00tradema
rk,00is00the00name00given00to00a00drug00by00its00manufacture
r.00The00nonproprietary,00or00generic,00name00is00provided00
by00the00United00States00Adopted00Names00Council.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.009
OBJ:001NAT:00NCLEX00Client00Needs00Category:00Safe,00Effect
ive00Care00Environment00TOP:0 0 Nursing00Process00Step:00Assessment
CON:0
0Patient00Education
2. Which00source00contains00information00specific00to00nutritional00supplements?
a. USP00Dictionary00of00USAN00 &00International00Drug00Names
b. Natural00Medicines00Comprehensive00Database
c. United00States00Pharmacopoeia/National00Formulary00(USP00NF)
d. Drug00Interaction00Facts
ANS:00 C
United00States00Pharmacopoeia/National00Formulary00contains00information00specific00to00nut
ritional00supplements.00USP00Dictionary00of00USAN00&00International00Drug00Names00is00a00
compilation00of00drug00names,00pronunciation00guide,00and00possible00future00FDA00approved
00drugs;00it00does00not00include00nutritional00supplements.00 Natural00Medicines00Comprehens
ive00Database00contains
evidence-
based00information00on00herbal00medicines00and00herbal00combination00products;00it00does00not
00include00information00specific00to00nutritional00supplements.00Drug00Interaction00Facts00con
tains00comprehensive00information00on00drug00interaction00facts;00it00does00not00include00nutr
itional00supplements.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.004
OBJ:00300NAT:0 0 NCLEX00Client00Needs00Category:00Physiologi
cal00Integrity
TOP:0 0 Nursing00Process00Step:00Assessment CON:0 0 Nutrition00|00Patient00Education
3. Which00drug00reference00contains00drug00monographs00that00describe00all00drugs00in00a00therapeutic00cl
ass?
a. Drug00Facts00and00Comparisons
,Test00Bank00For00Clayton’s00Basic00Pharmacology00for00Nurses0019 3
th00Edition
b. Drug00Interaction00Facts
c. Handbook00on00Injectable00Drugs
d. Martindale—The00Complete00Drug00Reference
ANS:00 A
Drug00Facts00and00Comparisons00contains00drug00monographs00that00describe00all00
drugs00in00a00therapeutic00class.00Monographs00are00formatted00as00tables00to00allow00c
omparison00of00similar00products,00brand00names,00manufacturers,00cost00indices,00and
00available00dosage00forms00Online00version00is00available.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.00400Table001.2
OBJ:000000 3 NAT:0 0 NCLEX00Client00Needs00Category:00Physiological00Integrity
TOP:0 0 Nursing00Process00Step:00Assessment
CON:0 0 Safety00|00Patient00Education00|00Clinical00Judgment
4. Which00drug00reference00contains00monographs00about00 virtually00every00single-
entity00drug00available00in00the00United00States00and00describes00therapeutic00uses00of00drugs,
00including00approved00and00unapproved00uses?
a. Martindale:00The00Complete00Drug00Reference
b. AHFS00Drug00Information
c. Drug00 Reference
d. Drug00Facts00and00Comparisons
ANS:00 B
AHFS00Drug00Information00contains00monographs00about00virtually00every00single-
entity00drug00available00in00the00United00States00and00describes00therapeutic00uses00of00drugs,0
0 including00approved00and00unapproved00uses.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.00400Table001.2
OBJ:000000 3 NAT:0 0 NCLEX00Client00Needs00Category:00Physiological00Integrity
TOP:0 0 Nursing00Process00Step:00Planning CON:0 0 Safety00|00Patient00Education00|00Clinical00Judgment
5. Which00online00drug00reference00makes00available00to00healthcare00providers00and00the00
public00a00standard,00comprehensive,00up-to-
date00look00up00and00downloadable00resource00about00medicines?
a. American00Drug00Index
b. American00Hospital00Formulary
c. DailyMed
d. Drug00Reference
ANS:00 C
DailyMed00makes00available00to00healthcare00providers00and00the00public00a00standard,00com
prehensive,00up-to-
date00look00up00and00downloadable00resource00about00medicines.00The00American00Drug00Ind
ex00is00not00appropriate00for00patient00use.00The00American00Hospital00Formulary00is00not00ap
propriate00for00patient00 use.00The00drug00reference00 is00not00appropriate00for00patient00 use.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.00300|00p.004
OBJ:00300NAT:0 0 NCLEX00Client00Needs00Category:00Physiologi
cal00Integrity
TOP:0 0 Nursing00Process00Step:00Implementation
CON:0 0 Safety00|00Patient00Education00|00Clinical00Judgment
6. Which00legislation00authorizes00the00FDA00to00determine00the00safety00of00a00drug00before00its00marketi
ng?
a. Federal00Food,00Drug,00and00Cosmetic00Act00(1938)
b. Durham00Humphrey00Amendment00(1952)
, Test00Bank00For00Clayton’s00Basic00Pharmacology00for00Nurses0019 4
th00Edition
c. Controlled00Substances00Act00(1970)
d. Kefauver00Harris00Drug00Amendment00(1962)
ANS:00 A
The00Federal00Food,00Drug,00and00Cosmetic00Act00of00193800authorized00the00FDA00to00dete
rmine00the00safety00of00all00drugs00before00marketing.00Later00amendments00and00acts00helpe
d00tighten00FDA00control00and00ensure00drug00safety.00The00Durham00Humphrey00Amendme
nt00defines00the00kinds00of00drugs00that00cannot00be00used00safely00without00medical00supervi
sion00and00restricts00their00sale00to00prescription00by00a00licensed00practitioner.00The00Controll
ed00Substances00Act00addresses00only00controlled00substances00and00their00categorization.00The
00Kefauver00Harris00Drug00Amendment00ensures00drug00efficacy00and00greater00drug00safety.00
Drug00manufacturers00are00required00to00prove00to00the00FDA00the00effectiveness00of00their00
products00before00marketing00them.
DIF: Cognitive00Level:00Knowledge REF:00p.00500Table00l.3
OBJ:0 0 5
NAT:00NCLEX00Client00Needs00Category:00Physiological00I
ntegrity00TOP:0 0 Nursing00Process00Step:00Assessment
CON:0 0 Safety00|00Patient00Education00|00Evidence00|00Health00Care00Law
7. Which00classification00does00meperidine00(Demerol)00fall00under?
a. I
b. II
c. III
d. IV
ANS:00 B
Meperidine00(Demerol)00is00a00Schedule00II00drug;00it00has00a00high00potential00for00abuse00a
nd00may00lead00to00severe00psychological00and00physical00dependence.00Schedule00I00drugs00ha
ve00high00potential00for00abuse00and00no00recognized00medical00use.00Schedule00III00drugs00ha
ve00some00potential00for00abuse.00Use00may00lead00to00low00to00moderate00physical00depende
nce00or00high00psychological00dependence.00Schedule00IV00drugs00have00low00potential00for00
abuse.00Use00may00lead00to00limited00physical00or00psychological00dependence.
DIF: Cognitive00Level:00Knowledge REF:0 0 p.0010
OBJ:00200NAT:0 0 NCLEX00Client00Needs00Category:00Safe,00Effe
ctive00Care00Environment
TOP:0 0 Nursing00Process00Step:00Assessment CON:0 0 Patient00Education00|00Addiction00|00Pain
8. Which00action00would00the00FDA00take00to00expedite00drug00development00 and00approval00for0
0an00outbreak00of00smallpox?
a. List00smallpox00as00a00health00orphan00disease.
b. Omit00the00preclinical00research00phase.
c. Extend00the00clinical00research00phase.
d. Fast00track00the00investigational00drug.
ANS:00 D
Once00the00Investigational00New00Drug00Application00has00been00approved,00the00drug00can0
0receive00highest00priority00within00the00agency,00which00is00called00fast00tracking.00A00small
pox00outbreak00would00become00a00priority00concern00in00the00world.00Orphan00diseases00are
00not00researched00in00a00priority00manner.00Preclinical00research00is00not00omitted.00Extendin
g00any00phase00of00the00research00would00mean00a00longer00time00to00develop00a00vaccine.00The
00FDA00must00ensure00that00all00phases00of00the00preclinical00and00clinical00research00phase00 ha
ve00been00completed00in00a00safe00manner.
DIF: Cognitive00Level:00Knowledge REF:000000p.007 OBJ:0 0 5
