NSG552 Psychopharmacology Exam 1 QUESTIONS AND ANSWERS GRADED A+
Pharmacokinetics - what the body does to the drug
Pharmacodynamics - what the drug does to the body
inhibitors - increase serum levels of other drugs that are substrates of that enzyme
inducer - decrease serum levels of other drugs that are substrates of that enzyme
amydala - This structure is located on the ends of the hippocampus and is related to the emotions of fear
and anger.
thalamus - Relay station for sensory information
frontal lobe - The lobe at the front of the brain associated with movement, speech, and motivation
(executive functioning)
serotonin - derived from tryptophan and made in the Ralphe Nuclei
Noreepinephrine - made in the Locus Coeruleus and involved in noradrenergic pathways
gut, intestine - where 90% of serotonin receptors are found
dopamine - produced in the VTA and involved in the four major pathways
Tuberoinfundibular pathway - dopamine inhibits prolactin in this pathway
mesolimbic pathway - increased dopamine in this pathway is associated with positive symptoms
, mesocortical pathway - decreased dopamine in this pathway is associated with negative symptoms
nigrostriatal pathway - decreased dopamine in this pathway produces motor symptoms
GABA - main inhibitory neurotransmitter that induces calmness and relaxation
glutamate - main excitatory neurotransmitter
major organ that breaks down drugs in the body - liver
electrolyte imbalance commonly associated with psychotropic medication use - hyponatremia
half-life - the time needed to clear 50% of drugs from the plasma
tolerance - A process in which your body needs more and more of a drug to get the same effect,
necessitating an increase in dose
therapeutic index - ratio of toxic dose to effective dose
agonist - a molecule that, by binding to a receptor site, stimulates a response
partial agonist - a drug that binds to a receptor and causes a response that is less than that caused by a
full agonist (doesn't fully activate the receptor)
antagonist - a chemical that binds to a receptor, blocking it to inhibit a biologic response
inverse agonist - an agent that binds to the same receptor as an agonist but induces a pharmacological
response opposite to that agonist
Pharmacokinetics - what the body does to the drug
Pharmacodynamics - what the drug does to the body
inhibitors - increase serum levels of other drugs that are substrates of that enzyme
inducer - decrease serum levels of other drugs that are substrates of that enzyme
amydala - This structure is located on the ends of the hippocampus and is related to the emotions of fear
and anger.
thalamus - Relay station for sensory information
frontal lobe - The lobe at the front of the brain associated with movement, speech, and motivation
(executive functioning)
serotonin - derived from tryptophan and made in the Ralphe Nuclei
Noreepinephrine - made in the Locus Coeruleus and involved in noradrenergic pathways
gut, intestine - where 90% of serotonin receptors are found
dopamine - produced in the VTA and involved in the four major pathways
Tuberoinfundibular pathway - dopamine inhibits prolactin in this pathway
mesolimbic pathway - increased dopamine in this pathway is associated with positive symptoms
, mesocortical pathway - decreased dopamine in this pathway is associated with negative symptoms
nigrostriatal pathway - decreased dopamine in this pathway produces motor symptoms
GABA - main inhibitory neurotransmitter that induces calmness and relaxation
glutamate - main excitatory neurotransmitter
major organ that breaks down drugs in the body - liver
electrolyte imbalance commonly associated with psychotropic medication use - hyponatremia
half-life - the time needed to clear 50% of drugs from the plasma
tolerance - A process in which your body needs more and more of a drug to get the same effect,
necessitating an increase in dose
therapeutic index - ratio of toxic dose to effective dose
agonist - a molecule that, by binding to a receptor site, stimulates a response
partial agonist - a drug that binds to a receptor and causes a response that is less than that caused by a
full agonist (doesn't fully activate the receptor)
antagonist - a chemical that binds to a receptor, blocking it to inhibit a biologic response
inverse agonist - an agent that binds to the same receptor as an agonist but induces a pharmacological
response opposite to that agonist
