Pharmaceutics Test 2 UHCOP Exam Q&A
100% Solved | Graded A+
Albumin Drug Site 1 - ✔✔thyroxine, WARFARIN, azidothymidine
(zidovudine), indomethacine
Albumin Drug Site 2 - ✔✔thyroxine, ibuprofen, diazepam, BENZO-site,
penicillins, tryptophan
Calcium disodium edetate - ✔✔lead poisoning
desferrioxamine - ✔✔acute iron poisoning
feosol (ferrous sulfate) - ✔✔anemia
Platinum: Cisplatin, Carboplatin - ✔✔cancer drugs (ovarian, lung)
cisplatin - dna binding
copper: hemocyanin - ✔✔makes lobster blood blue
cobalt - ✔✔vitamin b12 (cyanocobalalmin) binding
zinc - ✔✔insulin binding
1
©NINJANERD 2025/2026. YEAR PUBLISHED 2025.
, 2,3-dimercaptopropanol - ✔✔lead and mercury toxicity
cyclodextric (CD) complexes - ✔✔1) improve solubility
2) decrease degradation
3) lower toxicity
albumin - ✔✔binds acidic (-) charged drugs
Alpha 1 - acid glycoprotien - ✔✔binds basic (+) charged drugs
^ Ka (protein binding) - ✔✔^tighter binding to protein (albumin)
Class II Drug - ✔✔dose is greater than available binding sites
class I drug - ✔✔dose is less than available binding sites
result of giving class I drug with class II drug? - ✔✔-Class I drug will be
unable to bind and will increase in toxicity (more free drug available)
-Class II drug will take up all the binding sites
r/[D]=k-rk slope = - ✔✔-K = -Ka
r/[D]=k-rk y intercept = - ✔✔Ka
r/[D]=nk-rk n= - ✔✔# binding sites = y intercept/-k
2
©NINJANERD 2025/2026. YEAR PUBLISHED 2025.
100% Solved | Graded A+
Albumin Drug Site 1 - ✔✔thyroxine, WARFARIN, azidothymidine
(zidovudine), indomethacine
Albumin Drug Site 2 - ✔✔thyroxine, ibuprofen, diazepam, BENZO-site,
penicillins, tryptophan
Calcium disodium edetate - ✔✔lead poisoning
desferrioxamine - ✔✔acute iron poisoning
feosol (ferrous sulfate) - ✔✔anemia
Platinum: Cisplatin, Carboplatin - ✔✔cancer drugs (ovarian, lung)
cisplatin - dna binding
copper: hemocyanin - ✔✔makes lobster blood blue
cobalt - ✔✔vitamin b12 (cyanocobalalmin) binding
zinc - ✔✔insulin binding
1
©NINJANERD 2025/2026. YEAR PUBLISHED 2025.
, 2,3-dimercaptopropanol - ✔✔lead and mercury toxicity
cyclodextric (CD) complexes - ✔✔1) improve solubility
2) decrease degradation
3) lower toxicity
albumin - ✔✔binds acidic (-) charged drugs
Alpha 1 - acid glycoprotien - ✔✔binds basic (+) charged drugs
^ Ka (protein binding) - ✔✔^tighter binding to protein (albumin)
Class II Drug - ✔✔dose is greater than available binding sites
class I drug - ✔✔dose is less than available binding sites
result of giving class I drug with class II drug? - ✔✔-Class I drug will be
unable to bind and will increase in toxicity (more free drug available)
-Class II drug will take up all the binding sites
r/[D]=k-rk slope = - ✔✔-K = -Ka
r/[D]=k-rk y intercept = - ✔✔Ka
r/[D]=nk-rk n= - ✔✔# binding sites = y intercept/-k
2
©NINJANERD 2025/2026. YEAR PUBLISHED 2025.
