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Chemical Senses & The Brain (taste and smell)

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Unit 3 lecture 6 of NEU 101, In-depth notes on chemical senses as they relate to the brain.

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Chemical sense (taste & smell)
Vision reminer
Inner hair cells send to A1


Senses
There are 7 senses, but only cover 4


Chemical senses
Smell (Olfactory) & taste( gustation) are chemical senses

Some nociceptors and thermoreceptors can also be chemical

Why taste & smell?

Help us sort edible and non edible food

sweet more likely to be better, bitter more likely to be poison

Tend to prefer energy and nutrition rich food ( sugar & fat)

Social signaling (both within and in between species

for procreation or mood


Olfactory
How they get into our nose

There are air-born molecules (odorants)

Orthonasaly: From the outside world (going into the nose)

Retronasal: a smell from food already in our mouth

Transduction
Occurs once an outside molecule interacts with an olfactory receptor

Air containing chemicals gets into your nose




Chemical sense (taste & smell) 1

, Chemicals contact the mucosa (dime-sized region at top of the nasal cavity)

Olfactory receptor cells: embedded into mucosa

They have different shape binding sights

10 million with about 400 types

sensitive to different chemical odorents

Transduct chemicals into neural signals

Travel through bone

Cilia embedded into mucus,

Cell bodies supported by epithelium (supporting system )

Axons travel upward through bone

Theories of Olfaction
Shape & docking

We have receptors that pick out and bind specific odorant shapes

Like lock and key hypothesis

Vibration theory

The detection of smell is due to the vibration of molecules

each molecule has different frequencies in the infrared region

Olfactory bulb
Above the bone

where axons connect to

has different structures such as the the glomeruli

receives input from all olfactory nerves

Different types (400) have a specific type of synapse in the glomerulus

Chemotopic: smells that are similar synapse in the same area of the olfactory
bulb




Chemical sense (taste & smell) 2

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January 11, 2025
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Shannons eaton
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