UPDATED Questions with CORRECT
Answers
The urea cycle takes place in... - CORRECT ANSWER - the cytosol and the mitochondria
The reaction of ammonia with alpha-ketoglutarate is catalyzed by ______________ and requires
___________ as a reactant - CORRECT ANSWER - glutamate dehydrogenase, NADH or
NADPH
Ubiquitination is a means of targeting a protein for... - CORRECT ANSWER -
proteasomal degradation
What is an amino acid that is considered non-essential because it is generated by the urea cylce?
- CORRECT ANSWER - arginine
N-acetylgulatmate synthase is activated by... - CORRECT ANSWER - arginine
Most enzymes involved in protein digestion require cleavage for activation. These proteins are
secreted as inactive protein forms called: - CORRECT ANSWER - zymogens
What enzyme is active in both the fed and fasted states? - CORRECT ANSWER -
Glutaminase
What enzyme is regulated by N-acetyl glutamate? - CORRECT ANSWER - CPS 1
Pepsinogen is activated by what mechanism? - CORRECT ANSWER - A change in pH
catalyzes the activation of pepsinogen to pepsin
, What enzyme initiates the activation of pancreatic zymogens required for protein digestion? -
CORRECT ANSWER - enteropeptidase
What compound stimulates the synthesis of N-acetylglutamate? - CORRECT ANSWER -
arginine
What is the primary role of glutaminase in the liver? - CORRECT ANSWER - To free
amine group from glutamine
The pancreatic zymogen trypsinogen is activated by what enzyme? - CORRECT
ANSWER - enteropeptidase
In the case of urea cycle deficiency, what amino acid may become essential? - CORRECT
ANSWER - arginine
Unlike many of the other metabolic pathways the urea cycle can be active under which
conditions? - CORRECT ANSWER - both the fed and fasted state
When is the process of autophage most likely occuring within the cell? - CORRECT
ANSWER - when there is low energy in the cell; ratio of AMP/ATP > 1
During the urea cycle, what reaction takes place in mitochondria? - CORRECT
ANSWER - synthesis of carbamoyl phosphate
During the fasted state of nitrogen transport, glutaminase... - CORRECT ANSWER - will
be active
Alanine can be shuttled from the skeletal muscle to the liver where it is deaminated by the
enzyme... - CORRECT ANSWER - alanine aminotrasferase