CLINICAL CHEM QUESTIONS | TESTED AND PROVEN
ANSWERS | LATEST UPDATE 2024/2025 100%
(GRADE A+)
"The point at which the concentration of a drug is in equilibrium with the rate of dose
Administration and the rate of elimination" is the definition of which term below:
Bioavailability quotient
minimum effective concentration
therapeutic range
steady state
Ans>> steady state
"PTA is reduced by urate in alkaline medium and tungsten blue develops; color change is read at
650 to 700 nanometers. protein must be removed, and many other substances also interfere." This
is a description of which assay method?
Phosphotungstic acid method for uric acid determination
Urease method for BUN determination
Purified terephthalic acid method for ammonia determination
Uricase method for uric acid determination
1
,Ans>> Phosphotungstic acid method for uric acid determination
Why is bone disease a consequence of chronic kidney disease (CKD)?
the synthesis of EPO by peritubular fibroblasts decreases because of reduced red blood cell
survival
The juxtaglomerular apparatus no longer synthesizes renin in CKD, which keeps calcium phosphate
complexes from mineralizing
the basement membrane in Bowman's capsule is damaged and calcium is lost in the glomerular
filtrate
When glomerular filtration declines, vitamin D activation decreases resulting in reduced calcium,
which further leads to resorption of calcium from bone.
Ans>> When glomerular filtration declines, vitamin D activation decreases resulting in reduced
calcium, which further leads to resorption of calcium from bone.
Which tests would be most useful for differentiating acute pancreatitis from a perforated peptic
ulcer, since the symptoms are similar?
total CK and CKMB
serum amylase and lipase
2
,alkaline phosphatase and GGT
AST and ALT
Ans>> serum amylase and lipase
Which one of the following statements is correct concerning the oral glucose tolerance test (OGTT)
A fasting blood glucose concentration of 85 mg/dL and a 2-hour glucose value of 190mg/dL
indicates impaired glucose tolerance
for good results patients are required to fast for 72 hours before the OGTT
a fasting blood glucose concentration of 100 mg/dL and a 2-hour glucose value of 16 mg/dL
are indicative of impaired glucose tolerance
the OGTT is a test of glycogen formation response to a glucose load by the liver
Ans>> A fasting blood glucose concentration of 85 mg/dL and a 2-hour glucose value of
190mg/dL indicates impaired glucose tolerance
Which of these tests can help assess lead levels?
A) none of these
B) coproporphyrin
C) zinc protoporphyrin
3
, D) benzoyl ecgonine
Ans>> C) zinc protoporphyrin
Which of these statements about ALP is true?
A. in normal adults, the primary tissue source is fast twitch skeletal muscle
B. pregnant women have higher serum ALP levels than other adults
C. serum ALP levels are lower in children than in adults
D. geriatric patients have lower serum ALP than other adults
Ans>> B. pregnant women have higher serum ALP levels than other adults
Which of these drugs is NOT included in a drugs of abuse screen?
A) opiates
B) theophylline
C) amphetamines
D) THC
Ans>> B) theophylline
4
ANSWERS | LATEST UPDATE 2024/2025 100%
(GRADE A+)
"The point at which the concentration of a drug is in equilibrium with the rate of dose
Administration and the rate of elimination" is the definition of which term below:
Bioavailability quotient
minimum effective concentration
therapeutic range
steady state
Ans>> steady state
"PTA is reduced by urate in alkaline medium and tungsten blue develops; color change is read at
650 to 700 nanometers. protein must be removed, and many other substances also interfere." This
is a description of which assay method?
Phosphotungstic acid method for uric acid determination
Urease method for BUN determination
Purified terephthalic acid method for ammonia determination
Uricase method for uric acid determination
1
,Ans>> Phosphotungstic acid method for uric acid determination
Why is bone disease a consequence of chronic kidney disease (CKD)?
the synthesis of EPO by peritubular fibroblasts decreases because of reduced red blood cell
survival
The juxtaglomerular apparatus no longer synthesizes renin in CKD, which keeps calcium phosphate
complexes from mineralizing
the basement membrane in Bowman's capsule is damaged and calcium is lost in the glomerular
filtrate
When glomerular filtration declines, vitamin D activation decreases resulting in reduced calcium,
which further leads to resorption of calcium from bone.
Ans>> When glomerular filtration declines, vitamin D activation decreases resulting in reduced
calcium, which further leads to resorption of calcium from bone.
Which tests would be most useful for differentiating acute pancreatitis from a perforated peptic
ulcer, since the symptoms are similar?
total CK and CKMB
serum amylase and lipase
2
,alkaline phosphatase and GGT
AST and ALT
Ans>> serum amylase and lipase
Which one of the following statements is correct concerning the oral glucose tolerance test (OGTT)
A fasting blood glucose concentration of 85 mg/dL and a 2-hour glucose value of 190mg/dL
indicates impaired glucose tolerance
for good results patients are required to fast for 72 hours before the OGTT
a fasting blood glucose concentration of 100 mg/dL and a 2-hour glucose value of 16 mg/dL
are indicative of impaired glucose tolerance
the OGTT is a test of glycogen formation response to a glucose load by the liver
Ans>> A fasting blood glucose concentration of 85 mg/dL and a 2-hour glucose value of
190mg/dL indicates impaired glucose tolerance
Which of these tests can help assess lead levels?
A) none of these
B) coproporphyrin
C) zinc protoporphyrin
3
, D) benzoyl ecgonine
Ans>> C) zinc protoporphyrin
Which of these statements about ALP is true?
A. in normal adults, the primary tissue source is fast twitch skeletal muscle
B. pregnant women have higher serum ALP levels than other adults
C. serum ALP levels are lower in children than in adults
D. geriatric patients have lower serum ALP than other adults
Ans>> B. pregnant women have higher serum ALP levels than other adults
Which of these drugs is NOT included in a drugs of abuse screen?
A) opiates
B) theophylline
C) amphetamines
D) THC
Ans>> B) theophylline
4
