NR565 / NR 565 Advanced Pharmacology Fundamentals
Midterm Exam Ques and Ans
100% Guarantee Pass
1. What are medication examples of Schedule II drugs?
Answer
-Ativan & Valium
-Fentanyl
-Oxycodone
-Methadone
2. What medications are Schedule III drugs?
Answer
-Xanax
-Tramadol
-anabolic steroids
-<90mg of codeine
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,3. What medications are Schedule IV drugs?
Answer
-Ativan
-Tramadol
-Methadone
-Adderall
4. Which schedule drugs can APRNs prescribe?
Answer
Schedule II through Schedule IV
5. examples of reasons for medication non-adherence
Answer
-too busy
-too expensive
-ran out
-forgetting
-traveling & busy
6. Distribution in medication in elderly can be affected in what ways?
Answer
-de- creased lean mass
-decreased albumin
-decreased body fat
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-slower gastric acidity
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,-slower absorption results in delayed response
7. In the elderly decrease albumin and decreased lean mass affects medica-
tions how?
Answer
medication binds to protein so decreased protein affects how medica- tion is
absorbed and distributed
8. In elderly decreased body fat affects medications how?
Answer
need fat to transport medications and some drug metabolism is dependent on
body weight
9. When prescribing medication, we must understand that liver function de-
clines with age due to....
Answer
decreased blood flow to the liver, decreased hepatic enzymes
10. What is the most important cause of adverse drug reactions?
Answer
***overpre- scribing/polypharmacy
***decreased renal excretion
-high drug dosages (start low & go slow)
-lack of monitoring medications
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,11. What can a poor metabolism phenotype do to a metabolism of a drug?
Answer
-
-slow or increase absorption
-slow the metabolism
-keep drug in body longer
-increase toxicity
12. How does poor metabolism affect a high or low therapeutic index?
Answer
-in- crease drug toxicity
(example plavix - clots & increased platelets)
13. Black box warning for Opioids
Answer
respiratory depression
14. Black box warning for Fentanyl
Answer
FATAL respiratory depression
15. Black box warning for Methadone (NP cannot prescribe)
Answer
QT interval prolongation
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,16. Black box warning for Codeine
Answer
-breastfeeding and infant death can occur
-10% of dose converts to morphine
17. Black box warning for hydromorphone & oxymorphone (NP cannot pre-
scribe long acting hydromorphone and oxymorphone)
Answer
-risk for high abuse & overdose
-respiratory depression
18. Black box warning for oxycodone (NP need additional training to prescribe
for chronic pain)
Answer
-HIGH potential for abuse
-respiratory depression
19. Meds that require special training for APNs to prescribe are...
Answer
-Opioids
-Fentanyl
-Methadone
-Codeine
-Hydromorphone & oxymorphone
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-Oxycodone
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,20. What are therapeutic uses for morphine?
Answer
MODERATE TO SEVERE PAIN
-acute pain
-post op/surgical pain
-end of life pain management
-MI
-labor & delivery
-cancer
21. What are therapeutic uses for Fentanyl?
Answer
BREAKTHROUGH PAIN surgical pain
severe pain
opioid tolerant patients
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,22. What are therapeutic uses for codeine?
Answer
MILD TO MODERATE PAIN
Cough
23. What is MME and when to use it?
Answer
morphine milligram equivalent used for overdose(OD)
assess where patient is at in their pain management and monitor them safely
24. What is the PDPM and when to use it?
Answer
-database to access to patient's prescription history of controlled substances
used to ensure safe prescribing to prevent overdosing and polypharmacy
-use prior to starting opioid therapy and during opioid therapy
25. Renal and hepatic insufficiencies with opioids
1)Codeine
Answer
stays in body longer & metabolism is effected
26. Renal and hepatic insufficiencies with opioids
2) Morphine
Jo
Answer
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ua
, neurotoxicity
27. Renal and hepatic insufficiencies with
opioids 3)Oxycodone
Answer
overdose
can use with extreme caution and reduction of dosage
28. Renal and hepatic insufficiencies with
opioids 4)Fentanyl
Answer
monitor closely for sedation
29. Risk factors for Opioid Use Disorder (OUD)
Answer
family history mental health disorder (anxiety, depression)
social factors
prior drug use
pain management
poly-substance abuse
prescribe post surgery for long period of time
30. When to prescribe Naloxone?
Answer
>50 mme/day prior hx of OD
concurrent benzo use
31. Drugs not safe to take with Opioids
Answer
Jo
Benzos Alcohol
sh
ua
Midterm Exam Ques and Ans
100% Guarantee Pass
1. What are medication examples of Schedule II drugs?
Answer
-Ativan & Valium
-Fentanyl
-Oxycodone
-Methadone
2. What medications are Schedule III drugs?
Answer
-Xanax
-Tramadol
-anabolic steroids
-<90mg of codeine
Jo
sh
ua
,3. What medications are Schedule IV drugs?
Answer
-Ativan
-Tramadol
-Methadone
-Adderall
4. Which schedule drugs can APRNs prescribe?
Answer
Schedule II through Schedule IV
5. examples of reasons for medication non-adherence
Answer
-too busy
-too expensive
-ran out
-forgetting
-traveling & busy
6. Distribution in medication in elderly can be affected in what ways?
Answer
-de- creased lean mass
-decreased albumin
-decreased body fat
Jo
-slower gastric acidity
sh
ua
,-slower absorption results in delayed response
7. In the elderly decrease albumin and decreased lean mass affects medica-
tions how?
Answer
medication binds to protein so decreased protein affects how medica- tion is
absorbed and distributed
8. In elderly decreased body fat affects medications how?
Answer
need fat to transport medications and some drug metabolism is dependent on
body weight
9. When prescribing medication, we must understand that liver function de-
clines with age due to....
Answer
decreased blood flow to the liver, decreased hepatic enzymes
10. What is the most important cause of adverse drug reactions?
Answer
***overpre- scribing/polypharmacy
***decreased renal excretion
-high drug dosages (start low & go slow)
-lack of monitoring medications
Jo
sh
ua
,11. What can a poor metabolism phenotype do to a metabolism of a drug?
Answer
-
-slow or increase absorption
-slow the metabolism
-keep drug in body longer
-increase toxicity
12. How does poor metabolism affect a high or low therapeutic index?
Answer
-in- crease drug toxicity
(example plavix - clots & increased platelets)
13. Black box warning for Opioids
Answer
respiratory depression
14. Black box warning for Fentanyl
Answer
FATAL respiratory depression
15. Black box warning for Methadone (NP cannot prescribe)
Answer
QT interval prolongation
Jo
sh
ua
,16. Black box warning for Codeine
Answer
-breastfeeding and infant death can occur
-10% of dose converts to morphine
17. Black box warning for hydromorphone & oxymorphone (NP cannot pre-
scribe long acting hydromorphone and oxymorphone)
Answer
-risk for high abuse & overdose
-respiratory depression
18. Black box warning for oxycodone (NP need additional training to prescribe
for chronic pain)
Answer
-HIGH potential for abuse
-respiratory depression
19. Meds that require special training for APNs to prescribe are...
Answer
-Opioids
-Fentanyl
-Methadone
-Codeine
-Hydromorphone & oxymorphone
Jo
-Oxycodone
sh
ua
,20. What are therapeutic uses for morphine?
Answer
MODERATE TO SEVERE PAIN
-acute pain
-post op/surgical pain
-end of life pain management
-MI
-labor & delivery
-cancer
21. What are therapeutic uses for Fentanyl?
Answer
BREAKTHROUGH PAIN surgical pain
severe pain
opioid tolerant patients
Jo
sh
ua
,22. What are therapeutic uses for codeine?
Answer
MILD TO MODERATE PAIN
Cough
23. What is MME and when to use it?
Answer
morphine milligram equivalent used for overdose(OD)
assess where patient is at in their pain management and monitor them safely
24. What is the PDPM and when to use it?
Answer
-database to access to patient's prescription history of controlled substances
used to ensure safe prescribing to prevent overdosing and polypharmacy
-use prior to starting opioid therapy and during opioid therapy
25. Renal and hepatic insufficiencies with opioids
1)Codeine
Answer
stays in body longer & metabolism is effected
26. Renal and hepatic insufficiencies with opioids
2) Morphine
Jo
Answer
sh
ua
, neurotoxicity
27. Renal and hepatic insufficiencies with
opioids 3)Oxycodone
Answer
overdose
can use with extreme caution and reduction of dosage
28. Renal and hepatic insufficiencies with
opioids 4)Fentanyl
Answer
monitor closely for sedation
29. Risk factors for Opioid Use Disorder (OUD)
Answer
family history mental health disorder (anxiety, depression)
social factors
prior drug use
pain management
poly-substance abuse
prescribe post surgery for long period of time
30. When to prescribe Naloxone?
Answer
>50 mme/day prior hx of OD
concurrent benzo use
31. Drugs not safe to take with Opioids
Answer
Jo
Benzos Alcohol
sh
ua
