Questions and Complete Solutions
Graded A+
Drug metabolism is influenced by client factors sterm-42uch as - Answer: age, smoking, caffeine intake,
or other medications.
Glutamate - Answer: Most abundant, principle excitatory neurotransmitter in the brain, constituting
60% of all neurotransmitters
Glutamate plays a major role in __________ & ____________ - Answer: leaning & memory in the CNS
Main on switch, excitatory - Answer: Glutamate
Non-essential amino acid that does not cross the brain barrier ______ - Answer: Glutamate
Decussation happens in glutamate pathway 2. describe decussation - Answer: crossing to the other side
of the body. causing muscles to contract. Due to decussation, a stroke on one side of the cortex will will
cause weakness on the opposite side of the body.
The vental statium has glutamate input from the __________, _____________, & _____________ -
Answer: prefrontal cortex, hippocampus, and the amygdala which are all critical components of the
reward circuitry
Too much glutamate causes - Answer: Parkinsons disease, Alzheimers Disease, & Huntingtons Disease
Cerebellum controls - Answer: motor coordination
Name the 3 types of ionotropic glutamate receptors - Answer: 1.alpha amino 3 hydroxy 5 methyl 4
isoxazolepropionic (AMPA)
2. Kainate
, 3. N-methyl-D-asparate (NMDA)
(AMPA) & Kainate are very simular and are considered as one - Answer: true
When glutamate binds to the AMPA/Kainate receptor it opens a Ligand-gated ion channel: Na+ & K+ are
exchanged - Answer: the exchange of the Na+ and K+ leads to the opening of voltage gated Na+
channels, triggering an action potential.
Neurotransmitters work with receptors in the brain to influence and regulate a range of processes,
including _______________and __________________performance. - Answer: emotions and mental
performance.
An understanding of neurotransmission and its relationship to psychiatric symptoms is foundational to
the safe, effective prescribing of - Answer: psychotropic medications.
Our emotions & mental performance are regulated and influenced by __________________ &
________________ in the brain - Answer: Neurotransmitters & receptors in the brain.
Behavioral symptoms may be related to malfunctioning neurons; these symptoms can be produced,
worsened, or relieved by drugs such as ___________________ medications that alter neurotransmitter
processes and functioning. - Answer: psychotropic medications
What client factor(s) impact the effect of psychotropic medications? - Answer: age, prescribed
medications, other over-the-counter medications, diet, and smoking can all impact drug metabolism.
When prescribing psychotropic medications, what factors should the NP consider when perscribing
psycotropic drugs - Answer: clients age
prescribed medicatioins
over the counter medications
diet
smoking status &
potential adverse effects all impacts drug metabolism