CLINICAL PHARMACOLOGY 11TH EDITION
WITH COMPLETE SOLUTIONS
Absorption - Answer-A drug moved from site of
administration to body fluids.
Adverse Reaction - Answer-Undesirable drug effect
Allergic reaction - Answer-Immediate hypersensitivity
reaction w/symptoms; it presents as itching hives
swelling & difficulty breathing
,Anaphylactic shock - Answer-sudden, severe
hypersensitivity reaction w/symptoms that progress
rapidly and may result in death if not treated;
Angioedma - Answer-localized wheals or swellings in
subcutaneous tissue or mucous membranes, which
may be due to an allergic response.
Controlled substances - Answer-Drugs that have the
potential for abuse and dependency, both physically
and psychological
,cumulative drug effect - Answer-When the body is
unable to metabolize & excrete one dose of a drug
before the next is given
Distribution - Answer-drug moves from circulation to
body tissue or a target site.
Drug idiosyncrasy - Answer-Any unusual or
abnormal response the differs from the response
normally expected to a specific drug and dosage.
, Drug tolerance - Answer-decreased response to a
drug, requiring an increase in dosage to achieve the
desire effect
Excretion - Answer-elimination of a drug from the
body
First-pass effect - Answer-action by which an oral
drug is absorbed and carried directly to the liver,
where it is inactived by enzymes before it enters the
general blood stream.