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PHAR 100 UPDATED ACTUAL Questions and CORRECT Answers

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PHAR 100 UPDATED ACTUAL Questions and CORRECT Answers Phase One Drug Trial - CORRECT ANSWER - Small number of people Absorption, distribution, elimination, and adverse effects are monitored Phase Two Drug Trial - CORRECT ANSWER - Small number of people Determines if drug is effective in treatmen

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PHAR 100 UPDATED ACTUAL Questions
and CORRECT Answers
Phase One Drug Trial - CORRECT ANSWER - Small number of people
Absorption, distribution, elimination, and adverse effects are monitored


Phase Two Drug Trial - CORRECT ANSWER - Small number of people
Determines if drug is effective in treatment


Phase Three Drug Trial - CORRECT ANSWER - Large number of people
Safety of drug is carefully studied


Potency - CORRECT ANSWER - Amount of drug that must be given to obtain a response



Efficacy - CORRECT ANSWER - Maximum effect of the drug



Paul Ehrlich - CORRECT ANSWER - Organoarsenic compounds
Salvarsan: syphilis treatment


Gerhard Domagk - CORRECT ANSWER - Sulfonamides
Prontosil: streptococcus


Antimetabolites - CORRECT ANSWER - Act against substances required for metabolism
of an organism
Example: sulfanilamide


Sulfanilamide - CORRECT ANSWER - Antimetabolite

, Therapeutic Index - CORRECT ANSWER - Lethal Dose (Toxicity) ÷ Effective Dose
Higher means safer


Parenteral Routes - CORRECT ANSWER - Intramuscular
Subcutaneous
Intravenous


Enteral Routes - CORRECT ANSWER - Mouth
Rectal
Under Tongue


Drug Dependence - CORRECT ANSWER - Physical dependence
Psychological dependence
Tolerance


Abuse Potential - CORRECT ANSWER - Dependence liability
Availability of drug
Harmfulness


CNS Depressants - CORRECT ANSWER - Alcohol
Barbiturates
Benzodiazepines


Sedative-Hypnotics - CORRECT ANSWER - Barbiturates
Benzodiazepines


Benzodiazepines - CORRECT ANSWER - Activate GABA

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