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Samenvatting geneesmiddelen tabel - cholesterol

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Samenvatting van 2 pagina's voor het vak Verpleegkundige zorg en Communicatie 2 aan de HoGent (cholesterol)

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IP Werking Farmaca
Statines
Fibraten - Agonisten van nucleaire PPAR - Hyperlipen
– alfa - Lipanthyl
- PPAR- alfa: verantwoordelijk
voor de genexpressie van
verschillende enzymen
betrokken bij het
lipidenmetabolisme, maar
exact mechanisme is niet
gekend.
- Minder cholesterolverlagend,
wel triglyceridenverlagend

Anionuitwisselaars = - Binden galzouten in de darm Questran
glazuurbindende harsen en onderbreken zo hun
entero-hepatische cyclus
zonder zelf opgenomen te
worden (en zullen via faeces
darm verlaten)
 lever maakt meer
galzuren aan uit
cholesterol dus moet LDL
uit bloed halen om zelf
voldoende cholesterol te
hebben
Ezetimibe = - inhibeert selectief de Ezetrol
cholesterolabosrptieremmer intesinale resorptie van
cholesterol en zal wel door
lever gemetaboliseerd
worden via gal uitgescheden
- daling van cholesterol en LDL
cholesterol
- weinig effect op triglyceriden
en HDL cholesterol

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Uploaded on
January 3, 2025
Number of pages
2
Written in
2024/2025
Type
Summary
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