NURS6630 ///NURS 6630 PSYCHOPHARMACOLOGY MIDTERM EXAM 2 VERSIONS ACTUAL MIDTERM EXAM SUMMER QRT| EXAM QUESTIONS AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) |||ALREADY GRADED A+|||NEWEST VERSION

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NURS6630 ///NURS 6630
PSYCHOPHARMACOLOGY MIDTERM EXAM 2
VERSIONS ACTUAL MIDTERM EXAM SUMMER
QRT|2025-2026 EXAM QUESTIONS AND
CORRECT DETAILED ANSWERS (VERIFIED
ANSWERS) |||ALREADY GRADED A+|||NEWEST
VERSION
Serotonin regulates

Ans: Mood, emotion, feeding, and reproductive behavior




This class of antidepressants binds to presynaptic SERT and inhibits them from reuptake of

serotonin to increase levels in the synaptic cleft to bind with postsysnaptic 5HT2 receptors

Ans: SSRIs




First line therapy for MDD due to milder side effect profiles

Ans: SSRIs




Six Common SSRIs

Ans: citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline, paroxetine




Onset of therapeutic benefit from SSRIs



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Ans: 4-6 weeks




In addition to MDD, SSRIs also treat

Ans: Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia)




Five Common side effects of SSRIs include

Ans: Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH




Severe side effect of SSRIs in children/adolescents under age 25 years old

Ans: suicidal ideation




Life threatening adverse effect of SSRIs, especially when used in combination with other

serotonergic drugs (SNRIs, TCAs, MAOIs, etc.)

Ans: Serotonin Syndrome




Excess accumulation of serotonin resulting in overstimulation of the nervous system

Ans: Serotonin Syndrome




Seven symptoms of Serotonin Syndrome



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Ans: Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma, HYPERreflexia




The treatment for serotonin syndrome

Ans: Cyproheptadine (5-HT2 receptor antagonist)




Cyproheptadine treats serotonin syndrome by

Ans: blocking 5-HT2 receptors (serotonin antagonist)




When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal include

Ans: Irritability, headaches, and insomnia




Medicine specific side effect of citalopram

Ans: Prolonged QT interval (normal=0.4.-0.44 seconds)




This SSRI is pregnancy category D due to associations with congenital heart defects

Ans: Paroxetine




All SSRIs but paroxetine (D) are pregnancy category

Ans: C


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Three SSRIs that are inhibitors of Cytochrome P450 enzymes

Ans: fluoxetine, fluvoxamine, and paroxetine




Five common SNRIs include

Ans: duloxetine, venlafaxine, desvenlafaxine, milnacipran, levomilnacipran




This antidepressant class of medications works by binding to presynaptic SERT and NET to

inhibit them from reuptake of serotonin and norepinephrine to increase their levels in the

synaptic cleft

Ans: SNRIs




In addition to MDD SNRIs treat

Ans: Anxiety and neuropathic pain (peripheral neuropathy)




Medication specific indications of duloxetine:

Ans: urinary incontinence and Fibromyalgia




Medication specific indications of venlafaxine:

Ans: social anxiety, panic disorders, PTSD, OCD, postmenopausal hot flashes

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