PATHOLOGY ASSISTANT ASCP EXAM QUESTIONS
AND ANSWERS WITH SOLUTIONS
Megloblastic Anemia - ANSWER -B12 (Neurologic dysfunction)
Folic Acid (no neuro symptoms)
Vitamin A Deficiency - ANSWER -Night blindness and squamous metaplasia
Berbiberi - ANSWER -B1 deficiency
Dry: Peripheral Neuropathy
Wet: increased output, cardiac failure
Marasmus - ANSWER -Deficient in all neutrients
Kwashiorkor - ANSWER -Protein deficient
Right Coronary Artery - ANSWER -Posterior RV free wall and septum
Posterior LV
Left Circumflex (from left coronary: right dominant) - ANSWER -LV lateral wall
Left Anterior Descending - ANSWER -Apex
Anterior LV
Anterior 2/3 Ventricular septum
Arteriolosclerosis - ANSWER -Hyaline thickening in vessels (kidneys, hypertension,
diabetes)
Atherosclerosis - ANSWER -Plaques (atheroma) in vessels
Arteriosclerosis - ANSWER -rigidity, thickening of vessels
Monckeberg Arteriosclerosis - ANSWER -Radial and ulnar arteries, calcific sclerosis of
the media of arteries (so blood flow is not obstructed)
Subacute Bacterial Endocarditis - ANSWER -Streptococcus Viridans, mitral valve ( also
include aortic valve)
IV Drug users= Strep viridans and triscupid valve
Large, soft, friable easily detached vegetations
Complications: ulceration of valves, perforation of cusps, rupture of chordae tendineae
Nonbacterial Endocarditis (Marantic endocarditis) - ANSWER -Metastatic cancer,
wasting conditions
,Small, sterile fibrin deposits randomly arranged along the line of the valve leaflets
Peripheral emboliztion
Sterile emboli
Libman-Sacks Endocarditis - ANSWER -Lupus
Small vegetations on either or both surfaces of valve leaflets
Endocarditis Carcinoid Syndrome - ANSWER -Right side cusps thickened endocardial
plaques
Rubella (German Measles) - ANSWER -Risk highest shortly before conception to 16th
wk gestation
Right Sided Heart Failure - ANSWER -Left sided heart failure
Pulmonary hypertension
Right valvular disease (tricuspid and pulmonary)
Left-sided lesions (mitral stenosis)
Congestive hepatosplenomegaly and renal hypoxia
Nutmeg Liver
Distention of neck veins
Left Sided Heart Failure - ANSWER -Ischemic Heart Disease (MI)
Hypertension
Left valvular disease (aortic and mitral)
Myocardial diseases
Dyspnea and orthopnea
Pleural effusion with hydrothorax
Reduction in renal perfusion
Cerebral anoxia
Pulmonary edema
Subependymal Hemorrhage - ANSWER -Lateral ventricles of brain, premature infants
Necrotizing Enterocolitis - ANSWER -Severe and sudden onset of inflammation of
small and large intestines
Trisomy 13 - ANSWER -Patau Syndrome
Polydactyly
"Rocker Bottom" feet
Malignant Mesothelioma - ANSWER -Visceral or Parietal pleura (spreads through
pleural space)
Epithelioid- 70%
Sarcomatoid-20%
Biphasie-10%
, Sickle Cell Anemia - ANSWER -Recessive
transfusions, nonhealing leg ulcers, recurrent abdominal and chest pains
Autosplenomegaly
Susceptible to Haemophilus Influenzae infection
Glucose-6-Phosphate Dehydrogenase - ANSWER -X-linked
Black females
Enzyme deficient hemolytic anemia
"bite cells" on RBC smear
Hereditary Spherocytosis - ANSWER -White people
Intracorpuscular hemolytic anemia
Splenomegaly, erythrocyte osmotic fragility
Nodular Sclerosis Hodgkin Lymphoma - ANSWER -Young women
Lymph nodes are nodular with fibrous bands
Multiple Lacunar cells
Good Prognosis
Lymphocyte-predominance Hodgkin Lymphoma - ANSWER -Reed-Sternberg Cells
Young-Middle aged men
Good Prognosis
Mixed Cellularity Hodgkin Lymphoma - ANSWER -Reed-Sternberg Cells
Old men
Necrosis and fibrosis
EBV association
Okay prognosis
Lymphocyte Depletion Hodgkin Lymphoma - ANSWER -Reed-Sternberg Cells
Necrosis and fibrosis
EBV association
HIV association
Poor prognosis
Berylliosis - ANSWER -Exposure to beryllium
Sarcoidosis - ANSWER -Noncaseating granulomas
Dyspnea, fatigue, chest pain, nonproductive cough
Black women?
Diffuse densities within the lung
Idiopathic Pulmonary Fibrosis - ANSWER -Honeycomb lung
Chronic inflammation and fibrosis of alveolar wall
Resembles Goodpasture Syndrome without renal component
AND ANSWERS WITH SOLUTIONS
Megloblastic Anemia - ANSWER -B12 (Neurologic dysfunction)
Folic Acid (no neuro symptoms)
Vitamin A Deficiency - ANSWER -Night blindness and squamous metaplasia
Berbiberi - ANSWER -B1 deficiency
Dry: Peripheral Neuropathy
Wet: increased output, cardiac failure
Marasmus - ANSWER -Deficient in all neutrients
Kwashiorkor - ANSWER -Protein deficient
Right Coronary Artery - ANSWER -Posterior RV free wall and septum
Posterior LV
Left Circumflex (from left coronary: right dominant) - ANSWER -LV lateral wall
Left Anterior Descending - ANSWER -Apex
Anterior LV
Anterior 2/3 Ventricular septum
Arteriolosclerosis - ANSWER -Hyaline thickening in vessels (kidneys, hypertension,
diabetes)
Atherosclerosis - ANSWER -Plaques (atheroma) in vessels
Arteriosclerosis - ANSWER -rigidity, thickening of vessels
Monckeberg Arteriosclerosis - ANSWER -Radial and ulnar arteries, calcific sclerosis of
the media of arteries (so blood flow is not obstructed)
Subacute Bacterial Endocarditis - ANSWER -Streptococcus Viridans, mitral valve ( also
include aortic valve)
IV Drug users= Strep viridans and triscupid valve
Large, soft, friable easily detached vegetations
Complications: ulceration of valves, perforation of cusps, rupture of chordae tendineae
Nonbacterial Endocarditis (Marantic endocarditis) - ANSWER -Metastatic cancer,
wasting conditions
,Small, sterile fibrin deposits randomly arranged along the line of the valve leaflets
Peripheral emboliztion
Sterile emboli
Libman-Sacks Endocarditis - ANSWER -Lupus
Small vegetations on either or both surfaces of valve leaflets
Endocarditis Carcinoid Syndrome - ANSWER -Right side cusps thickened endocardial
plaques
Rubella (German Measles) - ANSWER -Risk highest shortly before conception to 16th
wk gestation
Right Sided Heart Failure - ANSWER -Left sided heart failure
Pulmonary hypertension
Right valvular disease (tricuspid and pulmonary)
Left-sided lesions (mitral stenosis)
Congestive hepatosplenomegaly and renal hypoxia
Nutmeg Liver
Distention of neck veins
Left Sided Heart Failure - ANSWER -Ischemic Heart Disease (MI)
Hypertension
Left valvular disease (aortic and mitral)
Myocardial diseases
Dyspnea and orthopnea
Pleural effusion with hydrothorax
Reduction in renal perfusion
Cerebral anoxia
Pulmonary edema
Subependymal Hemorrhage - ANSWER -Lateral ventricles of brain, premature infants
Necrotizing Enterocolitis - ANSWER -Severe and sudden onset of inflammation of
small and large intestines
Trisomy 13 - ANSWER -Patau Syndrome
Polydactyly
"Rocker Bottom" feet
Malignant Mesothelioma - ANSWER -Visceral or Parietal pleura (spreads through
pleural space)
Epithelioid- 70%
Sarcomatoid-20%
Biphasie-10%
, Sickle Cell Anemia - ANSWER -Recessive
transfusions, nonhealing leg ulcers, recurrent abdominal and chest pains
Autosplenomegaly
Susceptible to Haemophilus Influenzae infection
Glucose-6-Phosphate Dehydrogenase - ANSWER -X-linked
Black females
Enzyme deficient hemolytic anemia
"bite cells" on RBC smear
Hereditary Spherocytosis - ANSWER -White people
Intracorpuscular hemolytic anemia
Splenomegaly, erythrocyte osmotic fragility
Nodular Sclerosis Hodgkin Lymphoma - ANSWER -Young women
Lymph nodes are nodular with fibrous bands
Multiple Lacunar cells
Good Prognosis
Lymphocyte-predominance Hodgkin Lymphoma - ANSWER -Reed-Sternberg Cells
Young-Middle aged men
Good Prognosis
Mixed Cellularity Hodgkin Lymphoma - ANSWER -Reed-Sternberg Cells
Old men
Necrosis and fibrosis
EBV association
Okay prognosis
Lymphocyte Depletion Hodgkin Lymphoma - ANSWER -Reed-Sternberg Cells
Necrosis and fibrosis
EBV association
HIV association
Poor prognosis
Berylliosis - ANSWER -Exposure to beryllium
Sarcoidosis - ANSWER -Noncaseating granulomas
Dyspnea, fatigue, chest pain, nonproductive cough
Black women?
Diffuse densities within the lung
Idiopathic Pulmonary Fibrosis - ANSWER -Honeycomb lung
Chronic inflammation and fibrosis of alveolar wall
Resembles Goodpasture Syndrome without renal component
