Exam Bank for GMS655- Questions and Answers (Rated A+)

Exam Bank for GMS655- Questions and Answers (Rated A+) which definition best describes a lead compound? •the compound that is used for in vivo experiments •the compound the is used for clinical trials •the first compound discovered to have the desired activity •the compound that is FDA approved - Answers the first compound discovered to have the desired activity which method of discovering a drug is generally the least expensive? •natural products •high-throughput screening •molecular docking - Answers molecular docking what is the name of the process that involves step-wise alteration of a drug to improve its properties? •structure activity relationship •ADME •target identification •assay development - Answers structure activity relationship what was the estimated research and development expenses of pharma in 2016? •30 million •30 bilion •60 million •60 billion - Answers 60 billion which branch of pharmacology studies the effect of the body on drugs? •pharmacokinetics •pharmacodynamics •pharmacogenetics •pharmacotherapeutics •toxicology - Answers pharmacokinetics which branch of pharmacology studies how patients respond differently to drugs? •pharmacokinetics •pharmacodynamics •pharmacogenetics •pharmacotherapeutics •toxicology - Answers pharmacogenetics which branch of pharmacology studies the desired effect of drugs on the body, usually at the molecular level? •pharmacokinetics •pharmacodynamics •pharmacogenetics •pharmacotherapeutics •toxicology - Answers pharmacodynamics which branch of pharmacology studies adverse effects of drugs on the body? •pharmacokinetics •pharmacodynamics •pharmacogenetics •pharmacotherapeutics •toxicology - Answers toxicology which branch of pharmacology does excretion fall under? •pharmacokinetics •pharmacodynamics •pharmacogenetics •pharmacotherapeutics •toxicology - Answers pharmacokinetics which is the chemical name for a popular OTC painkiller? •tylenol •N-acetyl-para-aminophenol •acetaminophen - Answers N-acetyl-para-aminophenol which is the proprietary name for a popular OTC painkiller? •tylenol •N-acetyl-para-aminophenol •acetaminophen - Answers tylenol which is the non-proprietary name for a popular OTC painkiller? •tylenol •N-acetyl-para-aminophenol •acetaminophen - Answers acetaminophen which of the following are OTC drugs in the U.S.? select all that apply. •codeine •diphenhydramine •loperamide •levothyroxine •6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride •tadalafil - Answers •diphenhydramine •loperamide •6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride which of the following are only available as prescription drugs in the U.S.? select all that apply. •codeine •diphenhydramine •loperamide •levothyroxine •6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride •tadalafil - Answers •codeine •levothyroxine •tadalafil sally receives a year-long prescription from her physician for low-dose codeine that allows for 11 refills. her pharmacist will refuse to honor the full prescription because this is a schedule ___ controlled substance. •I •II •III •IV •V - Answers III which stage of translational research is the first to utilize a FDA approved drug? •T0 •T1 •T2 •T3 •T4 •T5 - Answers T3 for which of the following parts of translational research is patient involvement critical? choose all that apply. •public health •basic research •pre-clinical research •clinical research •clinical implementation - Answers •public health •basic research •pre-clinical research •clinical research •clinical implementation the transition between which two phases of translational research involves switching from controlled settings to real-world settings?