NURS8024/ NURS 8024 PHARM EXAM 1 |
NEWEST ACTUAL EXAM COMPREHENSIVE
QUESTIONS AND VERIFIED ANSWERS
GRADED A+ | 100% PASS | 2025 UPDATE!
Declines in hearing, vision, and manual dexterity have what effect on
pharmacokinetics and pharmacodynamics in in the eldery? - ✔✔✔
Correct Answer > result in unintentional overdose and
noncompliance with medication regimens
Acne Pathogenesis and drug mechanisms - ✔✔✔ Correct Answer >
Decline in resting heart rate, stroke volume, and cardiac output has
what effect on pharmacokinetics and pharmacodynamics in the
elderly? - ✔✔✔ Correct Answer > slows absorption, distribution, and
excretion of drugs
Benzoyl peroxide - ✔✔✔ Correct Answer > • Used in acne vulgaris
• Penetrates stratum corneum or follicular openings
• MOA-antimicrobial, peeling and comeolytic effects
• Start low concentration (2.5%) to ↓ irritation (wk. 1)
• Increase as tolerated
,• Avoid eyes & MM
• Can cause bleaching of hair & fabric
Azelaic Acid - ✔✔✔ Correct Answer > • Used in acne vulgaris
(Azelex) and in acne rosacea (Finacea)
• MOA-not fully understood, antimicrobial
• 20% cream or 15% gel daily x 1wk then BID
• ADE-mild irritation, erythema & dryness
• Clinical improvement in 6-8 wks
Topical Drugs for Psoriasis - ✔✔✔ Correct Answer > Acitretin
(soriatane)
Tazaroten (Tazorac)
Calcipotriene (synthetic Vit. D3) and Calcitriol (hormonally active form
of Vit. D3)
Acitretin (Soriatane) - ✔✔✔ Correct Answer > Retinoid derivative,
similar ADE as isotretinoin
- *BBW - for blood donation and pregnancy prohibited during Tx and 3
yrs after!*
- No ETOH- forms teratogen w/ longer half-life
,MOA of Tazarotene (Tazorac) - ✔✔✔ Correct Answer > Possible anti-
inflammatory and antiproliferative effects, possible teratogenicity,
don't use in pregnancy (but no BBW)
Biologic Agents for Psoriasis - ✔✔✔ Correct Answer > Used in
moderate to severe chronic placque psoriasis
- T-Cell modulator- alefacept
- TNF-a Inhibitors - Etanercept (Enbrel), Infliximab (Remicade);
Adalimumab (Humira)
- Cytokine Inhibitor (ustekinumab) Stelara
All cause immunosuppression, increased risk of serious infection, some
w/ increased risk of malignancies
Fungal Infections - ✔✔✔ Correct Answer > amongst the most
common causes of skin disease in the U.S.
• Superficial fungal infections caused by dermatophytic fungi may be
treated w/ topical antifungal agents
• Numerous effective topical and oral antifungal agents have been
developed
Superficial fungal infections caused by dermatophytic fungi should be
treated with - ✔✔✔ Correct Answer > topical agents or Oral agents
Topical Agents include
, -Clotrimazole
-Miconazole
- econazole
- ketoconazole
- oxiconazole
- Sulconazole
- sertaconazole
- ciclopirox olamine
- naftifine
-terbinafine (Lamisil)
- Butenafine (Mentax)
-tolnaftate (Aftage, Tinactin)
Oral Agents include
griseofulvin
terbinafine
fluconazole
itraconazole
Chronic generalized cutaneous candidiasis requires - ✔✔✔ Correct
Answer > long term oral therapy required
NEWEST ACTUAL EXAM COMPREHENSIVE
QUESTIONS AND VERIFIED ANSWERS
GRADED A+ | 100% PASS | 2025 UPDATE!
Declines in hearing, vision, and manual dexterity have what effect on
pharmacokinetics and pharmacodynamics in in the eldery? - ✔✔✔
Correct Answer > result in unintentional overdose and
noncompliance with medication regimens
Acne Pathogenesis and drug mechanisms - ✔✔✔ Correct Answer >
Decline in resting heart rate, stroke volume, and cardiac output has
what effect on pharmacokinetics and pharmacodynamics in the
elderly? - ✔✔✔ Correct Answer > slows absorption, distribution, and
excretion of drugs
Benzoyl peroxide - ✔✔✔ Correct Answer > • Used in acne vulgaris
• Penetrates stratum corneum or follicular openings
• MOA-antimicrobial, peeling and comeolytic effects
• Start low concentration (2.5%) to ↓ irritation (wk. 1)
• Increase as tolerated
,• Avoid eyes & MM
• Can cause bleaching of hair & fabric
Azelaic Acid - ✔✔✔ Correct Answer > • Used in acne vulgaris
(Azelex) and in acne rosacea (Finacea)
• MOA-not fully understood, antimicrobial
• 20% cream or 15% gel daily x 1wk then BID
• ADE-mild irritation, erythema & dryness
• Clinical improvement in 6-8 wks
Topical Drugs for Psoriasis - ✔✔✔ Correct Answer > Acitretin
(soriatane)
Tazaroten (Tazorac)
Calcipotriene (synthetic Vit. D3) and Calcitriol (hormonally active form
of Vit. D3)
Acitretin (Soriatane) - ✔✔✔ Correct Answer > Retinoid derivative,
similar ADE as isotretinoin
- *BBW - for blood donation and pregnancy prohibited during Tx and 3
yrs after!*
- No ETOH- forms teratogen w/ longer half-life
,MOA of Tazarotene (Tazorac) - ✔✔✔ Correct Answer > Possible anti-
inflammatory and antiproliferative effects, possible teratogenicity,
don't use in pregnancy (but no BBW)
Biologic Agents for Psoriasis - ✔✔✔ Correct Answer > Used in
moderate to severe chronic placque psoriasis
- T-Cell modulator- alefacept
- TNF-a Inhibitors - Etanercept (Enbrel), Infliximab (Remicade);
Adalimumab (Humira)
- Cytokine Inhibitor (ustekinumab) Stelara
All cause immunosuppression, increased risk of serious infection, some
w/ increased risk of malignancies
Fungal Infections - ✔✔✔ Correct Answer > amongst the most
common causes of skin disease in the U.S.
• Superficial fungal infections caused by dermatophytic fungi may be
treated w/ topical antifungal agents
• Numerous effective topical and oral antifungal agents have been
developed
Superficial fungal infections caused by dermatophytic fungi should be
treated with - ✔✔✔ Correct Answer > topical agents or Oral agents
Topical Agents include
, -Clotrimazole
-Miconazole
- econazole
- ketoconazole
- oxiconazole
- Sulconazole
- sertaconazole
- ciclopirox olamine
- naftifine
-terbinafine (Lamisil)
- Butenafine (Mentax)
-tolnaftate (Aftage, Tinactin)
Oral Agents include
griseofulvin
terbinafine
fluconazole
itraconazole
Chronic generalized cutaneous candidiasis requires - ✔✔✔ Correct
Answer > long term oral therapy required
