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The goal of translation - correct answer ✔accurately make proteins based on
the mRNA recipe sent from DNA
translation produces immature, linear proteins. "beads on a string" which is -
correct answer ✔a primary sequence of amino acids linked by peptide bonds
= polypeptide
To become mature proteins, polypeptides must - correct answer ✔fold into
their native structure
many polypeptides are modified through enzymatic processes to - correct
answer ✔facilitate folding, targeting and activation of proteins
N terminus is - correct answer ✔Positive
C terminus is - correct answer ✔Negative
Do stop codons code for amino acids? - correct answer ✔No, they tell the
ribosome to terminate translation via release factor
primary sequence of RNA is - correct answer ✔nucleotide sequence
primary sequence of proteins is - correct answer ✔amino acid sequence
Protein structure determines it's - correct answer ✔function
, Early notions of protein folding states - correct answer ✔templates must exist
that allowed for proteins to "copy" them and adopt their native structure
The issue with the hypothesis of protein folding being a template driven
process is - correct answer ✔how did the template fold, it must have a non-
template driven mechanism in order to fold
The folding of a protein into it's native state is NOT _____ - correct answer
✔template driven
Proteins can spontaneously fold into their native structures under - correct
answer ✔physiological conditions
In general under the proper conditions biological structures are - correct
answer ✔self-assembling
Rnase A functions to - correct answer ✔degrade RNA
Experiments in the 1950's by Christian Anfinsen took an enzyme, ______ ,
and "unfolded it" via chemical methods to an inactive form. When the
chemicals were removed, the enzyme refolded and was active again - correct
answer ✔Rnase A
Anfinsen's experiments suggest the folded state is the most - correct answer
✔thermodynamically stable
More thermodynamically favorable is the - correct answer ✔lower energy
state